Atlas of Genetics and Cytogenetics in Oncology and Haematology


Home   Genes   Leukemias   Solid Tumors   Cancer-Prone   Deep Insight   Case Reports   Journals  Portal   Teaching   

X Y 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22 NA

BICD1 (BICD cargo adaptor 1)

Identity

Alias_namesBicaudal D (Drosophila) homolog 1
bicaudal D homolog 1 (Drosophila)
Other aliasBICD
bic-D 1
HGNC (Hugo) BICD1
LocusID (NCBI) 636
Atlas_Id 54156
Location 5q14.1  [Link to chromosome band 5q14]
Location_base_pair Starts at 32106807 and ends at 32383633 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2017)
Data from Atlas, Mitelman, Cosmic Fusion, Fusion Cancer, TCGA fusion databases with official HUGO symbols (see references in chromosomal bands)
BICD1 (12p11.21) / BICD1 (12p11.21)BICD1 (12p11.21) / CCDC91 (12p11.22)BICD1 (12p11.21) / CDK6 (7q21.2)
BICD1 (12p11.21) / COG5 (7q22.3)BICD1 (12p11.21) / ETFBKMT (12p11.21)BICD1 (12p11.21) / KMT2C (7q36.1)
BICD1 (12p11.21) / PPP1R13L (19q13.32)BICD1 (12p11.21) / SOX5 (12p12.1)BICD1 (12p11.21) / SPAST (2p22.3)
BICD1 (12p11.21) / ZNF438 (10p11.23)CDH17 (8q22.1) / BICD1 (12p11.21)BICD1 12p11.21 / CCDC91 12p11.22
BICD1 12p11.21 / CDK6 7q21.2BICD1 12p11.21 / SOX5 12p12.1BICD1 12p11.21 / ZNF438 10p11.23

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


Other Solid tumors implicated (Data extracted from papers in the Atlas) [ 4 ]
  t(7;12)(q21;p11) BICD1/CDK6
t(10;12)(p11;p11) BICD1/ZNF438
BICD1/CCDC91 (12p11)
t(12;12)(p11;p12) BICD1/SOX5


External links

Nomenclature
HGNC (Hugo)BICD1   1049
Cards
Entrez_Gene (NCBI)BICD1  636  BICD cargo adaptor 1
AliasesBICD; bic-D
GeneCards (Weizmann)BICD1
Ensembl hg19 (Hinxton)ENSG00000151746 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000151746 [Gene_View]  ENSG00000151746 [Sequence]  chr12:32106807-32383633 [Contig_View]  BICD1 [Vega]
ICGC DataPortalENSG00000151746
TCGA cBioPortalBICD1
AceView (NCBI)BICD1
Genatlas (Paris)BICD1
WikiGenes636
SOURCE (Princeton)BICD1
Genetics Home Reference (NIH)BICD1
Genomic and cartography
GoldenPath hg38 (UCSC)BICD1  -     chr12:32106807-32383633 +  5q14.1   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)BICD1  -     5q14.1   [Description]    (hg19-Feb_2009)
EnsemblBICD1 - 5q14.1 [CytoView hg19]  BICD1 - 5q14.1 [CytoView hg38]
Mapping of homologs : NCBIBICD1 [Mapview hg19]  BICD1 [Mapview hg38]
OMIM602204   
Gene and transcription
Genbank (Entrez)AA207154 AA249429 AK095648 AK290188 AK313430
RefSeq transcript (Entrez)NM_001003398 NM_001354186 NM_001354187 NM_001354188 NM_001354189 NM_001363603 NM_001714
RefSeq genomic (Entrez)
Consensus coding sequences : CCDS (NCBI)BICD1
Cluster EST : UnigeneHs.633204 [ NCBI ]
CGAP (NCI)Hs.633204
Alternative Splicing GalleryENSG00000151746
Gene ExpressionBICD1 [ NCBI-GEO ]   BICD1 [ EBI - ARRAY_EXPRESS ]   BICD1 [ SEEK ]   BICD1 [ MEM ]
Gene Expression Viewer (FireBrowse)BICD1 [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevestigatorExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)636
GTEX Portal (Tissue expression)BICD1
Human Protein AtlasENSG00000151746-BICD1 [pathology]   [cell]   [tissue]
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ96G01   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtQ96G01  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProQ96G01
Splice isoforms : SwissVarQ96G01
PhosPhoSitePlusQ96G01
Domains : Interpro (EBI)BICD   
Domain families : Pfam (Sanger)BicD (PF09730)   
Domain families : Pfam (NCBI)pfam09730   
Conserved Domain (NCBI)BICD1
DMDM Disease mutations636
Blocks (Seattle)BICD1
SuperfamilyQ96G01
Human Protein Atlas [tissue]ENSG00000151746-BICD1 [tissue]
Peptide AtlasQ96G01
HPRD03730
IPIIPI00018368   IPI00062115   IPI00337563   IPI01022287   IPI01021970   IPI01022081   IPI00794021   
Protein Interaction databases
DIP (DOE-UCLA)Q96G01
IntAct (EBI)Q96G01
FunCoupENSG00000151746
BioGRIDBICD1
STRING (EMBL)BICD1
ZODIACBICD1
Ontologies - Pathways
QuickGOQ96G01
Ontology : AmiGOstructural constituent of cytoskeleton  protein binding  Golgi apparatus  Golgi apparatus  trans-Golgi network  centrosome  cytosol  cytosol  cytoskeleton  cytoplasmic microtubule  RNA processing  cytoskeletal adaptor activity  intracellular mRNA localization  anatomical structure morphogenesis  membrane  viral process  Rab GTPase binding  protein kinase binding  cytoplasmic vesicle  proteinase activated receptor binding  protein localization to organelle  stress granule assembly  dynactin binding  dynactin binding  tubulin complex  dynein intermediate chain binding  positive regulation of receptor-mediated endocytosis  perinuclear region of cytoplasm  perinuclear region of cytoplasm  regulation of microtubule cytoskeleton organization  dynein complex binding  minus-end-directed organelle transport along microtubule  microtubule anchoring at microtubule organizing center  host cell viral assembly compartment  negative regulation of phospholipase C activity  regulation of proteinase activated receptor activity  negative regulation of phospholipase C-activating G-protein coupled receptor signaling pathway  positive regulation of protein localization to centrosome  
Ontology : EGO-EBIstructural constituent of cytoskeleton  protein binding  Golgi apparatus  Golgi apparatus  trans-Golgi network  centrosome  cytosol  cytosol  cytoskeleton  cytoplasmic microtubule  RNA processing  cytoskeletal adaptor activity  intracellular mRNA localization  anatomical structure morphogenesis  membrane  viral process  Rab GTPase binding  protein kinase binding  cytoplasmic vesicle  proteinase activated receptor binding  protein localization to organelle  stress granule assembly  dynactin binding  dynactin binding  tubulin complex  dynein intermediate chain binding  positive regulation of receptor-mediated endocytosis  perinuclear region of cytoplasm  perinuclear region of cytoplasm  regulation of microtubule cytoskeleton organization  dynein complex binding  minus-end-directed organelle transport along microtubule  microtubule anchoring at microtubule organizing center  host cell viral assembly compartment  negative regulation of phospholipase C activity  regulation of proteinase activated receptor activity  negative regulation of phospholipase C-activating G-protein coupled receptor signaling pathway  positive regulation of protein localization to centrosome  
NDEx NetworkBICD1
Atlas of Cancer Signalling NetworkBICD1
Wikipedia pathwaysBICD1
Orthology - Evolution
OrthoDB636
GeneTree (enSembl)ENSG00000151746
Phylogenetic Trees/Animal Genes : TreeFamBICD1
HOVERGENQ96G01
HOGENOMQ96G01
Homologs : HomoloGeneBICD1
Homology/Alignments : Family Browser (UCSC)BICD1
Gene fusions - Rearrangements
Fusion : MitelmanBICD1/CCDC91 [12p11.21/12p11.22]  
Fusion : MitelmanBICD1/CDK6 [12p11.21/7q21.2]  [t(7;12)(q21;p11)]  
Fusion : MitelmanBICD1/METTL20 [12p11.21/12p11.21]  [dup(12)(p11p11)]  
Fusion : MitelmanBICD1/SOX5 [12p11.21/12p12.1]  [t(12;12)(p11;p12)]  
Fusion : MitelmanBICD1/ZNF438 [12p11.21/10p11.23]  [t(10;12)(p11;p11)]  
Fusion PortalBICD1 12p11.21 CCDC91 12p11.22 PRAD
Fusion PortalBICD1 12p11.21 CDK6 7q21.2 LUAD
Fusion PortalBICD1 12p11.21 SOX5 12p12.1 LGG
Fusion PortalBICD1 12p11.21 ZNF438 10p11.23 LGG
Fusion : QuiverBICD1
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerBICD1 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)BICD1
dbVarBICD1
ClinVarBICD1
1000_GenomesBICD1 
Exome Variant ServerBICD1
ExAC (Exome Aggregation Consortium)ENSG00000151746
GNOMAD BrowserENSG00000151746
Varsome BrowserBICD1
Genetic variants : HAPMAP636
Genomic Variants (DGV)BICD1 [DGVbeta]
DECIPHERBICD1 [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisBICD1 
Mutations
ICGC Data PortalBICD1 
TCGA Data PortalBICD1 
Broad Tumor PortalBICD1
OASIS PortalBICD1 [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICBICD1  [overview]  [genome browser]  [tissue]  [distribution]  
Mutations and Diseases : HGMDBICD1
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD - Leiden Open Variation Database
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
BioMutasearch BICD1
DgiDB (Drug Gene Interaction Database)BICD1
DoCM (Curated mutations)BICD1 (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)BICD1 (select a term)
intoGenBICD1
Cancer3DBICD1(select the gene name)
Impact of mutations[PolyPhen2] [Provean] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM602204   
Orphanet
DisGeNETBICD1
MedgenBICD1
Genetic Testing Registry BICD1
NextProtQ96G01 [Medical]
TSGene636
GENETestsBICD1
Target ValidationBICD1
Huge Navigator BICD1 [HugePedia]
snp3D : Map Gene to Disease636
BioCentury BCIQBICD1
ClinGenBICD1
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD636
Chemical/Pharm GKB GenePA25352
Clinical trialBICD1
Miscellaneous
canSAR (ICR)BICD1 (select the gene name)
Probes
Litterature
PubMed42 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineBICD1
EVEXBICD1
GoPubMedBICD1
iHOPBICD1
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

Search in all EBI   NCBI

© Atlas of Genetics and Cytogenetics in Oncology and Haematology
indexed on : Thu Aug 16 10:49:30 CEST 2018

Home   Genes   Leukemias   Solid Tumors   Cancer-Prone   Deep Insight   Case Reports   Journals  Portal   Teaching   

For comments and suggestions or contributions, please contact us

jlhuret@AtlasGeneticsOncology.org.