Atlas of Genetics and Cytogenetics in Oncology and Haematology

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BICD2 (BICD cargo adaptor 2)

Identity

Alias_namesbicaudal D homolog 2 (Drosophila)
Alias_symbol (synonym)KIAA0699
Other aliasSMALED2
SMALED2A
SMALED2B
bA526D8.1
HGNC (Hugo) BICD2
LocusID (NCBI) 23299
Atlas_Id 46791
Location 9q22.31  [Link to chromosome band 9q22]
Location_base_pair Starts at 92711363 and ends at 92764801 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2017)		Data from Atlas, Mitelman, Cosmic Fusion, Fusion Cancer, TCGA fusion databases with official HUGO symbols (see references in chromosomal bands)
BICD2 (9q22.31) / BICD2 (9q22.31)BICD2 (9q22.31) / JAK2 (9p24.1)

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 

Other Leukemias implicated (Data extracted from papers in the Atlas) [ 1 ]
  t(9;9)(p24;q22) BICD2/JAK2

External links

Nomenclature
HGNC (Hugo)BICD2   17208
Cards
Entrez_Gene (NCBI)BICD2  23299  BICD cargo adaptor 2
AliasesSMALED2; SMALED2A; SMALED2B; bA526D8.1
GeneCards (Weizmann)BICD2
Ensembl hg19 (Hinxton)ENSG00000185963 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000185963 [Gene_View]  ENSG00000185963 [Sequence]  chr9:92711363-92764801 [Contig_View]  BICD2 [Vega]
ICGC DataPortalENSG00000185963
TCGA cBioPortalBICD2
AceView (NCBI)BICD2
Genatlas (Paris)BICD2
WikiGenes23299
SOURCE (Princeton)BICD2
Genetics Home Reference (NIH)BICD2
Genomic and cartography
GoldenPath hg38 (UCSC)BICD2  -     chr9:92711363-92764801 -  9q22.31   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)BICD2  -     9q22.31   [Description]    (hg19-Feb_2009)
GoldenPathBICD2 - 9q22.31 [CytoView hg19]  BICD2 - 9q22.31 [CytoView hg38]
ImmunoBaseENSG00000185963
Mapping of homologs : NCBIBICD2 [Mapview hg19]  BICD2 [Mapview hg38]
OMIM609797   615290   618291   
Gene and transcription
Genbank (Entrez)AB014599 AY052562 BC004296 BC010428 BC073970
RefSeq transcript (Entrez)NM_001003800 NM_015250
RefSeq genomic (Entrez)
Consensus coding sequences : CCDS (NCBI)BICD2
Cluster EST : UnigeneHs.436939 [ NCBI ]
CGAP (NCI)Hs.436939
Alternative Splicing GalleryENSG00000185963
Gene ExpressionBICD2 [ NCBI-GEO ]   BICD2 [ EBI - ARRAY_EXPRESS ]   BICD2 [ SEEK ]   BICD2 [ MEM ]
Gene Expression Viewer (FireBrowse)BICD2 [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevestigatorExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)23299
GTEX Portal (Tissue expression)BICD2
Human Protein AtlasENSG00000185963-BICD2 [pathology]   [cell]   [tissue]
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ8TD16   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtQ8TD16  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProQ8TD16
Splice isoforms : SwissVarQ8TD16
PhosPhoSitePlusQ8TD16
Domains : Interpro (EBI)BICD   
Domain families : Pfam (Sanger)BicD (PF09730)   
Domain families : Pfam (NCBI)pfam09730   
Conserved Domain (NCBI)BICD2
DMDM Disease mutations23299
Blocks (Seattle)BICD2
SuperfamilyQ8TD16
Human Protein Atlas [tissue]ENSG00000185963-BICD2 [tissue]
Peptide AtlasQ8TD16
HPRD09826
IPIIPI00178185   IPI00337667   IPI00386676   
Protein Interaction databases
DIP (DOE-UCLA)Q8TD16
IntAct (EBI)Q8TD16
FunCoupENSG00000185963
BioGRIDBICD2
STRING (EMBL)BICD2
ZODIACBICD2
Ontologies - Pathways
QuickGOQ8TD16
Ontology : AmiGOprotein binding  nuclear envelope  annulate lamellae  nuclear pore  cytoplasm  Golgi apparatus  Golgi apparatus  centrosome  cytosol  cytosol  plasma membrane  retrograde vesicle-mediated transport, Golgi to ER  retrograde vesicle-mediated transport, Golgi to ER  microtubule-based movement  cytoskeletal adaptor activity  protein transport  Rab GTPase binding  Rab GTPase binding  cytoplasmic vesicle  protein localization to Golgi apparatus  protein localization to Golgi apparatus  dynactin binding  dynactin binding  mRNA transport  centrosome localization  dynein light intermediate chain binding  dynein light intermediate chain binding  regulation of microtubule cytoskeleton organization  regulation of microtubule cytoskeleton organization  dynein complex binding  dynein complex binding  minus-end-directed organelle transport along microtubule  microtubule anchoring at microtubule organizing center  microtubule anchoring at microtubule organizing center  
Ontology : EGO-EBIprotein binding  nuclear envelope  annulate lamellae  nuclear pore  cytoplasm  Golgi apparatus  Golgi apparatus  centrosome  cytosol  cytosol  plasma membrane  retrograde vesicle-mediated transport, Golgi to ER  retrograde vesicle-mediated transport, Golgi to ER  microtubule-based movement  cytoskeletal adaptor activity  protein transport  Rab GTPase binding  Rab GTPase binding  cytoplasmic vesicle  protein localization to Golgi apparatus  protein localization to Golgi apparatus  dynactin binding  dynactin binding  mRNA transport  centrosome localization  dynein light intermediate chain binding  dynein light intermediate chain binding  regulation of microtubule cytoskeleton organization  regulation of microtubule cytoskeleton organization  dynein complex binding  dynein complex binding  minus-end-directed organelle transport along microtubule  microtubule anchoring at microtubule organizing center  microtubule anchoring at microtubule organizing center  
NDEx NetworkBICD2
Atlas of Cancer Signalling NetworkBICD2
Wikipedia pathwaysBICD2
Orthology - Evolution
OrthoDB23299
GeneTree (enSembl)ENSG00000185963
Phylogenetic Trees/Animal Genes : TreeFamBICD2
HOGENOMQ8TD16
Homologs : HomoloGeneBICD2
Homology/Alignments : Family Browser (UCSC)BICD2
Gene fusions - Rearrangements
Fusion : QuiverBICD2
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerBICD2 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)BICD2
dbVarBICD2
ClinVarBICD2
1000_GenomesBICD2 
Exome Variant ServerBICD2
ExAC (Exome Aggregation Consortium)ENSG00000185963
GNOMAD BrowserENSG00000185963
Varsome BrowserBICD2
Genetic variants : HAPMAP23299
Genomic Variants (DGV)BICD2 [DGVbeta]
DECIPHERBICD2 [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisBICD2 
Mutations
ICGC Data PortalBICD2 
TCGA Data PortalBICD2 
Broad Tumor PortalBICD2
OASIS PortalBICD2 [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICBICD2  [overview]  [genome browser]  [tissue]  [distribution]  
Somatic Mutations in Cancer : COSMIC3DBICD2
Mutations and Diseases : HGMDBICD2
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD - Leiden Open Variation Database
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
BioMutasearch BICD2
DgiDB (Drug Gene Interaction Database)BICD2
DoCM (Curated mutations)BICD2 (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)BICD2 (select a term)
intoGenBICD2
Cancer3DBICD2(select the gene name)
Impact of mutations[PolyPhen2] [Provean] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM609797    615290    618291   
Orphanet22307   
DisGeNETBICD2
MedgenBICD2
Genetic Testing Registry BICD2
NextProtQ8TD16 [Medical]
TSGene23299
GENETestsBICD2
Target ValidationBICD2
Huge Navigator BICD2 [HugePedia]
snp3D : Map Gene to Disease23299
BioCentury BCIQBICD2
ClinGenBICD2
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD23299
Chemical/Pharm GKB GenePA134969018
Clinical trialBICD2
Miscellaneous
canSAR (ICR)BICD2 (select the gene name)
DataMed IndexBICD2
Probes
Litterature
PubMed52 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineBICD2
EVEXBICD2
GoPubMedBICD2
iHOPBICD2
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

Search in all EBI   NCBI

© Atlas of Genetics and Cytogenetics in Oncology and Haematology
indexed on : Wed Nov 13 17:34:13 CET 2019
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