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BID (BH3 interacting domain death agonist)

Identity

Other namesFP497
HGNC (Hugo) BID
LocusID (NCBI) 637
Atlas_Id 792
Location 22q11.21
Location_base_pair Starts at 18216906 and ends at 18257261 bp from pter ( according to hg19-Feb_2009)
Fusion genes
(updated 2016)
BID (22q11.21) / COPG1 (3q21.3)BID (22q11.21) / NOP58 (2q33.1)BID (22q11.21) / SLC4A1AP (2p23.3)

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


External links

Nomenclature
HGNC (Hugo)BID   1050
Cards
Entrez_Gene (NCBI)BID  637  BH3 interacting domain death agonist
GeneCards (Weizmann)BID
Ensembl hg19 (Hinxton)ENSG00000015475 [Gene_View]  chr22:18216906-18257261 [Contig_View]  BID [Vega]
Ensembl hg38 (Hinxton)ENSG00000015475 [Gene_View]  chr22:18216906-18257261 [Contig_View]  BID [Vega]
ICGC DataPortalENSG00000015475
TCGA cBioPortalBID
AceView (NCBI)BID
Genatlas (Paris)BID
WikiGenes637
SOURCE (Princeton)BID
Genomic and cartography
GoldenPath hg19 (UCSC)BID  -     chr22:18216906-18257261 -  22q11.21   [Description]    (hg19-Feb_2009)
GoldenPath hg38 (UCSC)BID  -     22q11.21   [Description]    (hg38-Dec_2013)
EnsemblBID - 22q11.21 [CytoView hg19]  BID - 22q11.21 [CytoView hg38]
Mapping of homologs : NCBIBID [Mapview hg19]  BID [Mapview hg38]
OMIM601997   
Gene and transcription
Genbank (Entrez)AF042083 AF087891 AF250233 AF370380 AK094795
RefSeq transcript (Entrez)NM_001196 NM_001244567 NM_001244569 NM_001244570 NM_001244572 NM_197966 NM_197967
RefSeq genomic (Entrez)NC_000022 NC_018933 NT_187355 NW_004929429
Consensus coding sequences : CCDS (NCBI)BID
Cluster EST : UnigeneHs.591054 [ NCBI ]
CGAP (NCI)Hs.591054
Alternative Splicing GalleryENSG00000015475
Gene ExpressionBID [ NCBI-GEO ]   BID [ EBI - ARRAY_EXPRESS ]   BID [ SEEK ]   BID [ MEM ]
Gene Expression Viewer (FireBrowse)BID [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevisibleExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)637
GTEX Portal (Tissue expression)BID
Protein : pattern, domain, 3D structure
UniProt/SwissProtP55957 (Uniprot)
NextProtP55957  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProP55957
Splice isoforms : SwissVarP55957 (Swissvar)
PhosPhoSitePlusP55957
Domaine pattern : Prosite (Expaxy)BH3 (PS01259)   
Domains : Interpro (EBI)Bcl2_BH3_motif_CS    BID   
Domain families : Pfam (Sanger)BID (PF06393)   
Domain families : Pfam (NCBI)pfam06393   
DMDM Disease mutations637
Blocks (Seattle)BID
PDB (SRS)1ZY3    2BID    2KBW    2M5B    2M5I    4BD2    4QVE    4ZEQ    4ZIG    4ZII    5AJJ   
PDB (PDBSum)1ZY3    2BID    2KBW    2M5B    2M5I    4BD2    4QVE    4ZEQ    4ZIG    4ZII    5AJJ   
PDB (IMB)1ZY3    2BID    2KBW    2M5B    2M5I    4BD2    4QVE    4ZEQ    4ZIG    4ZII    5AJJ   
PDB (RSDB)1ZY3    2BID    2KBW    2M5B    2M5I    4BD2    4QVE    4ZEQ    4ZIG    4ZII    5AJJ   
Structural Biology KnowledgeBase1ZY3    2BID    2KBW    2M5B    2M5I    4BD2    4QVE    4ZEQ    4ZIG    4ZII    5AJJ   
SCOP (Structural Classification of Proteins)1ZY3    2BID    2KBW    2M5B    2M5I    4BD2    4QVE    4ZEQ    4ZIG    4ZII    5AJJ   
CATH (Classification of proteins structures)1ZY3    2BID    2KBW    2M5B    2M5I    4BD2    4QVE    4ZEQ    4ZIG    4ZII    5AJJ   
SuperfamilyP55957
Human Protein AtlasENSG00000015475
Peptide AtlasP55957
HPRD03590
IPIIPI00413587   IPI00420084   IPI00385121   IPI00472003   IPI00978537   IPI00435963   
Protein Interaction databases
DIP (DOE-UCLA)P55957
IntAct (EBI)P55957
FunCoupENSG00000015475
BioGRIDBID
STRING (EMBL)BID
ZODIACBID
Ontologies - Pathways
QuickGOP55957
Ontology : AmiGOrelease of cytochrome c from mitochondria  death receptor binding  protein binding  mitochondrion  mitochondrial outer membrane  cytosol  protein targeting to mitochondrion  activation of cysteine-type endopeptidase activity involved in apoptotic process  brain development  extrinsic apoptotic signaling pathway via death domain receptors  apoptotic mitochondrial changes  membrane  ubiquitin protein ligase binding  response to estradiol  positive regulation of protein oligomerization  positive regulation of protein homooligomerization  integral component of mitochondrial membrane  glial cell apoptotic process  regulation of cell proliferation  signal transduction in response to DNA damage  regulation of apoptotic process  positive regulation of apoptotic process  protein homooligomerization  neuron apoptotic process  extracellular exosome  establishment of protein localization to membrane  positive regulation of release of cytochrome c from mitochondria  positive regulation of release of cytochrome c from mitochondria  hepatocyte apoptotic process  mitochondrial outer membrane permeabilization  positive regulation of protein insertion into mitochondrial membrane involved in apoptotic signaling pathway  positive regulation of mitochondrial outer membrane permeabilization involved in apoptotic signaling pathway  regulation of G1/S transition of mitotic cell cycle  positive regulation of extrinsic apoptotic signaling pathway  positive regulation of intrinsic apoptotic signaling pathway  
Ontology : EGO-EBIrelease of cytochrome c from mitochondria  death receptor binding  protein binding  mitochondrion  mitochondrial outer membrane  cytosol  protein targeting to mitochondrion  activation of cysteine-type endopeptidase activity involved in apoptotic process  brain development  extrinsic apoptotic signaling pathway via death domain receptors  apoptotic mitochondrial changes  membrane  ubiquitin protein ligase binding  response to estradiol  positive regulation of protein oligomerization  positive regulation of protein homooligomerization  integral component of mitochondrial membrane  glial cell apoptotic process  regulation of cell proliferation  signal transduction in response to DNA damage  regulation of apoptotic process  positive regulation of apoptotic process  protein homooligomerization  neuron apoptotic process  extracellular exosome  establishment of protein localization to membrane  positive regulation of release of cytochrome c from mitochondria  positive regulation of release of cytochrome c from mitochondria  hepatocyte apoptotic process  mitochondrial outer membrane permeabilization  positive regulation of protein insertion into mitochondrial membrane involved in apoptotic signaling pathway  positive regulation of mitochondrial outer membrane permeabilization involved in apoptotic signaling pathway  regulation of G1/S transition of mitotic cell cycle  positive regulation of extrinsic apoptotic signaling pathway  positive regulation of intrinsic apoptotic signaling pathway  
Pathways : BIOCARTARole of Mitochondria in Apoptotic Signaling [Genes]    Induction of apoptosis through DR3 and DR4/5 Death Receptors [Genes]    HIV-I Nef: negative effector of Fas and TNF [Genes]    Apoptotic Signaling in Response to DNA Damage [Genes]   
Pathways : KEGGp53 signaling pathway    Apoptosis    Natural killer cell mediated cytotoxicity    Non-alcoholic fatty liver disease (NAFLD)    Alzheimer's disease    Amyotrophic lateral sclerosis (ALS)    Tuberculosis    Pathways in cancer    Viral myocarditis   
NDEx Network
Atlas of Cancer Signalling NetworkBID
Wikipedia pathwaysBID
Orthology - Evolution
OrthoDB637
GeneTree (enSembl)ENSG00000015475
Phylogenetic Trees/Animal Genes : TreeFamBID
Homologs : HomoloGeneBID
Homology/Alignments : Family Browser (UCSC)BID
Gene fusions - Rearrangements
Polymorphisms : SNP, variants
NCBI Variation ViewerBID [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)BID
dbVarBID
ClinVarBID
1000_GenomesBID 
Exome Variant ServerBID
ExAC (Exome Aggregation Consortium)BID (select the gene name)
Genetic variants : HAPMAP637
Genomic Variants (DGV)BID [DGVbeta]
Mutations
ICGC Data PortalBID 
TCGA Data PortalBID 
Broad Tumor PortalBID
OASIS PortalBID [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICBID 
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD - Leiden Open Variation Database
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
LOVD (Leiden Open Variation Database)MSeqDR-LSDB Mitochondrial Disease Locus Specific Database
BioMutasearch BID
DgiDB (Drug Gene Interaction Database)BID
DoCM (Curated mutations)BID (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)BID (select a term)
intoGenBID
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] 
Diseases
DECIPHER (Syndromes)22:18216906-18257261  ENSG00000015475
CONAN: Copy Number AnalysisBID 
Mutations and Diseases : HGMDBID
OMIM601997   
MedgenBID
Genetic Testing Registry BID
NextProtP55957 [Medical]
TSGene637
GENETestsBID
Huge Navigator BID [HugePedia]
snp3D : Map Gene to Disease637
BioCentury BCIQBID
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD637
Chemical/Pharm GKB GenePA25353
Clinical trialBID
Miscellaneous
canSAR (ICR)BID (select the gene name)
Probes
Litterature
PubMed219 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineBID
EVEXBID
GoPubMedBID
iHOPBID
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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indexed on : Sun May 8 18:38:43 CEST 2016

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