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BIN3 (bridging integrator 3)

Identity

Other alias-
HGNC (Hugo) BIN3
LocusID (NCBI) 55909
Atlas_Id 60756
Location 8p21.3  [Link to chromosome band 8p21]
Location_base_pair Starts at 22620431 and ends at 22669148 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2017)
Data from Atlas, Mitelman, Cosmic Fusion, Fusion Cancer, TCGA fusion databases with official HUGO symbols (see references in chromosomal bands)
BIN3 (8p21.3) / PEBP4 (8p21.3)OR51B5 (11p15.4) / BIN3 (8p21.3)

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


External links

Nomenclature
HGNC (Hugo)BIN3   1054
Cards
Entrez_Gene (NCBI)BIN3  55909  bridging integrator 3
Aliases
GeneCards (Weizmann)BIN3
Ensembl hg19 (Hinxton)ENSG00000147439 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000147439 [Gene_View]  chr8:22620431-22669148 [Contig_View]  BIN3 [Vega]
ICGC DataPortalENSG00000147439
TCGA cBioPortalBIN3
AceView (NCBI)BIN3
Genatlas (Paris)BIN3
WikiGenes55909
SOURCE (Princeton)BIN3
Genetics Home Reference (NIH)BIN3
Genomic and cartography
GoldenPath hg38 (UCSC)BIN3  -     chr8:22620431-22669148 -  8p21.3   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)BIN3  -     8p21.3   [Description]    (hg19-Feb_2009)
EnsemblBIN3 - 8p21.3 [CytoView hg19]  BIN3 - 8p21.3 [CytoView hg38]
Mapping of homologs : NCBIBIN3 [Mapview hg19]  BIN3 [Mapview hg38]
OMIM606396   
Gene and transcription
Genbank (Entrez)AF271732 AK001289 AK023980 AK090446 AK124486
RefSeq transcript (Entrez)NM_018688
RefSeq genomic (Entrez)
Consensus coding sequences : CCDS (NCBI)BIN3
Cluster EST : UnigeneHs.433722 [ NCBI ]
CGAP (NCI)Hs.433722
Alternative Splicing GalleryENSG00000147439
Gene ExpressionBIN3 [ NCBI-GEO ]   BIN3 [ EBI - ARRAY_EXPRESS ]   BIN3 [ SEEK ]   BIN3 [ MEM ]
Gene Expression Viewer (FireBrowse)BIN3 [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevestigatorExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)55909
GTEX Portal (Tissue expression)BIN3
Human Protein AtlasENSG00000147439-BIN3 [pathology]   [cell]   [tissue]
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ9NQY0   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtQ9NQY0  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProQ9NQY0
Splice isoforms : SwissVarQ9NQY0
PhosPhoSitePlusQ9NQY0
Domaine pattern : Prosite (Expaxy)BAR (PS51021)   
Domains : Interpro (EBI)AH/BAR-dom    BAR_dom   
Domain families : Pfam (Sanger)BAR (PF03114)   
Domain families : Pfam (NCBI)pfam03114   
Domain families : Smart (EMBL)BAR (SM00721)  
Conserved Domain (NCBI)BIN3
DMDM Disease mutations55909
Blocks (Seattle)BIN3
SuperfamilyQ9NQY0
Human Protein Atlas [tissue]ENSG00000147439-BIN3 [tissue]
Peptide AtlasQ9NQY0
HPRD05904
IPIIPI00032966   IPI00556562   IPI00816016   IPI01014028   IPI00974021   IPI00974518   IPI00974188   
Protein Interaction databases
DIP (DOE-UCLA)Q9NQY0
IntAct (EBI)Q9NQY0
FunCoupENSG00000147439
BioGRIDBIN3
STRING (EMBL)BIN3
ZODIACBIN3
Ontologies - Pathways
QuickGOQ9NQY0
Ontology : AmiGOcytokinesis  barrier septum assembly  protein binding  cytoplasm  actin filament  actin filament organization  cytoskeletal adaptor activity  protein localization  unidimensional cell growth  regulation of lamellipodium assembly  myoblast migration involved in skeletal muscle regeneration  skeletal muscle fiber development  
Ontology : EGO-EBIcytokinesis  barrier septum assembly  protein binding  cytoplasm  actin filament  actin filament organization  cytoskeletal adaptor activity  protein localization  unidimensional cell growth  regulation of lamellipodium assembly  myoblast migration involved in skeletal muscle regeneration  skeletal muscle fiber development  
NDEx NetworkBIN3
Atlas of Cancer Signalling NetworkBIN3
Wikipedia pathwaysBIN3
Orthology - Evolution
OrthoDB55909
GeneTree (enSembl)ENSG00000147439
Phylogenetic Trees/Animal Genes : TreeFamBIN3
HOVERGENQ9NQY0
HOGENOMQ9NQY0
Homologs : HomoloGeneBIN3
Homology/Alignments : Family Browser (UCSC)BIN3
Gene fusions - Rearrangements
Fusion: Tumor Portal BIN3
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerBIN3 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)BIN3
dbVarBIN3
ClinVarBIN3
1000_GenomesBIN3 
Exome Variant ServerBIN3
ExAC (Exome Aggregation Consortium)ENSG00000147439
GNOMAD BrowserENSG00000147439
Genetic variants : HAPMAP55909
Genomic Variants (DGV)BIN3 [DGVbeta]
DECIPHERBIN3 [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisBIN3 
Mutations
ICGC Data PortalBIN3 
TCGA Data PortalBIN3 
Broad Tumor PortalBIN3
OASIS PortalBIN3 [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICBIN3  [overview]  [genome browser]  [tissue]  [distribution]  
Mutations and Diseases : HGMDBIN3
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD - Leiden Open Variation Database
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
BioMutasearch BIN3
DgiDB (Drug Gene Interaction Database)BIN3
DoCM (Curated mutations)BIN3 (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)BIN3 (select a term)
intoGenBIN3
Cancer3DBIN3(select the gene name)
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM606396   
Orphanet
MedgenBIN3
Genetic Testing Registry BIN3
NextProtQ9NQY0 [Medical]
TSGene55909
GENETestsBIN3
Target ValidationBIN3
Huge Navigator BIN3 [HugePedia]
snp3D : Map Gene to Disease55909
BioCentury BCIQBIN3
ClinGenBIN3
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD55909
Chemical/Pharm GKB GenePA25357
Clinical trialBIN3
Miscellaneous
canSAR (ICR)BIN3 (select the gene name)
Probes
Litterature
PubMed15 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineBIN3
EVEXBIN3
GoPubMedBIN3
iHOPBIN3
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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indexed on : Thu Nov 9 11:39:05 CET 2017

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