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BIRC7 (baculoviral IAP repeat containing 7)

Identity

Alias_namesbaculoviral IAP repeat-containing 7
Alias_symbol (synonym)mliap
ML-IAP
KIAP
RNF50
Other aliasLIVIN
MLIAP
HGNC (Hugo) BIRC7
LocusID (NCBI) 79444
Atlas_Id 799
Location 20q13.33  [Link to chromosome band 20q13]
Location_base_pair Starts at 63235883 and ends at 63240507 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2017)
Data from Atlas, Mitelman, Cosmic Fusion, Fusion Cancer, TCGA fusion databases with official HUGO symbols (see references in chromosomal bands)

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


External links

Nomenclature
HGNC (Hugo)BIRC7   13702
Cards
Entrez_Gene (NCBI)BIRC7  79444  baculoviral IAP repeat containing 7
AliasesKIAP; LIVIN; ML-IAP; MLIAP; 
RNF50
GeneCards (Weizmann)BIRC7
Ensembl hg19 (Hinxton)ENSG00000101197 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000101197 [Gene_View]  ENSG00000101197 [Sequence]  chr20:63235883-63240507 [Contig_View]  BIRC7 [Vega]
ICGC DataPortalENSG00000101197
TCGA cBioPortalBIRC7
AceView (NCBI)BIRC7
Genatlas (Paris)BIRC7
WikiGenes79444
SOURCE (Princeton)BIRC7
Genetics Home Reference (NIH)BIRC7
Genomic and cartography
GoldenPath hg38 (UCSC)BIRC7  -     chr20:63235883-63240507 +  20q13.33   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)BIRC7  -     20q13.33   [Description]    (hg19-Feb_2009)
EnsemblBIRC7 - 20q13.33 [CytoView hg19]  BIRC7 - 20q13.33 [CytoView hg38]
Mapping of homologs : NCBIBIRC7 [Mapview hg19]  BIRC7 [Mapview hg38]
OMIM605737   
Gene and transcription
Genbank (Entrez)AF301009 AF311388 AY358835 AY358836 AY517497
RefSeq transcript (Entrez)NM_022161 NM_139317
RefSeq genomic (Entrez)
Consensus coding sequences : CCDS (NCBI)BIRC7
Cluster EST : UnigeneHs.256126 [ NCBI ]
CGAP (NCI)Hs.256126
Alternative Splicing GalleryENSG00000101197
Gene ExpressionBIRC7 [ NCBI-GEO ]   BIRC7 [ EBI - ARRAY_EXPRESS ]   BIRC7 [ SEEK ]   BIRC7 [ MEM ]
Gene Expression Viewer (FireBrowse)BIRC7 [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevestigatorExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)79444
GTEX Portal (Tissue expression)BIRC7
Human Protein AtlasENSG00000101197-BIRC7 [pathology]   [cell]   [tissue]
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ96CA5   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtQ96CA5  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProQ96CA5
Splice isoforms : SwissVarQ96CA5
PhosPhoSitePlusQ96CA5
Domaine pattern : Prosite (Expaxy)BIR_REPEAT_1 (PS01282)    BIR_REPEAT_2 (PS50143)    ZF_RING_1 (PS00518)    ZF_RING_2 (PS50089)   
Domains : Interpro (EBI)BIR_rpt    Znf_RING    Znf_RING/FYVE/PHD    Znf_RING_CS   
Domain families : Pfam (Sanger)BIR (PF00653)   
Domain families : Pfam (NCBI)pfam00653   
Domain families : Smart (EMBL)BIR (SM00238)  RING (SM00184)  
Conserved Domain (NCBI)BIRC7
DMDM Disease mutations79444
Blocks (Seattle)BIRC7
PDB (SRS)1OXN    1OXQ    1OY7    1TW6    2I3H    2I3I    3F7G    3F7H    3F7I    3GT9    3GTA    3UW5    4AUQ   
PDB (PDBSum)1OXN    1OXQ    1OY7    1TW6    2I3H    2I3I    3F7G    3F7H    3F7I    3GT9    3GTA    3UW5    4AUQ   
PDB (IMB)1OXN    1OXQ    1OY7    1TW6    2I3H    2I3I    3F7G    3F7H    3F7I    3GT9    3GTA    3UW5    4AUQ   
PDB (RSDB)1OXN    1OXQ    1OY7    1TW6    2I3H    2I3I    3F7G    3F7H    3F7I    3GT9    3GTA    3UW5    4AUQ   
Structural Biology KnowledgeBase1OXN    1OXQ    1OY7    1TW6    2I3H    2I3I    3F7G    3F7H    3F7I    3GT9    3GTA    3UW5    4AUQ   
SCOP (Structural Classification of Proteins)1OXN    1OXQ    1OY7    1TW6    2I3H    2I3I    3F7G    3F7H    3F7I    3GT9    3GTA    3UW5    4AUQ   
CATH (Classification of proteins structures)1OXN    1OXQ    1OY7    1TW6    2I3H    2I3I    3F7G    3F7H    3F7I    3GT9    3GTA    3UW5    4AUQ   
SuperfamilyQ96CA5
Human Protein Atlas [tissue]ENSG00000101197-BIRC7 [tissue]
Peptide AtlasQ96CA5
HPRD05761
IPIIPI00152993   IPI00219046   IPI00853322   
Protein Interaction databases
DIP (DOE-UCLA)Q96CA5
IntAct (EBI)Q96CA5
FunCoupENSG00000101197
BioGRIDBIRC7
STRING (EMBL)BIRC7
ZODIACBIRC7
Ontologies - Pathways
QuickGOQ96CA5
Ontology : AmiGOubiquitin-protein transferase activity  cysteine-type endopeptidase inhibitor activity  protein binding  nucleus  nucleus  cytoplasm  cytoplasm  Golgi apparatus  microtubule organizing center  cytosol  apoptotic process  activation of JUN kinase activity  protein ubiquitination  enzyme binding  regulation of cell proliferation  cysteine-type endopeptidase inhibitor activity involved in apoptotic process  negative regulation of apoptotic process  negative regulation of apoptotic process  metal ion binding  ubiquitin protein ligase activity  regulation of natural killer cell apoptotic process  inhibition of cysteine-type endopeptidase activity involved in apoptotic process  
Ontology : EGO-EBIubiquitin-protein transferase activity  cysteine-type endopeptidase inhibitor activity  protein binding  nucleus  nucleus  cytoplasm  cytoplasm  Golgi apparatus  microtubule organizing center  cytosol  apoptotic process  activation of JUN kinase activity  protein ubiquitination  enzyme binding  regulation of cell proliferation  cysteine-type endopeptidase inhibitor activity involved in apoptotic process  negative regulation of apoptotic process  negative regulation of apoptotic process  metal ion binding  ubiquitin protein ligase activity  regulation of natural killer cell apoptotic process  inhibition of cysteine-type endopeptidase activity involved in apoptotic process  
Pathways : KEGGUbiquitin mediated proteolysis    Apoptosis    Toxoplasmosis    Pathways in cancer    Small cell lung cancer   
NDEx NetworkBIRC7
Atlas of Cancer Signalling NetworkBIRC7
Wikipedia pathwaysBIRC7
Orthology - Evolution
OrthoDB79444
GeneTree (enSembl)ENSG00000101197
Phylogenetic Trees/Animal Genes : TreeFamBIRC7
HOVERGENQ96CA5
HOGENOMQ96CA5
Homologs : HomoloGeneBIRC7
Homology/Alignments : Family Browser (UCSC)BIRC7
Gene fusions - Rearrangements
Fusion : QuiverBIRC7
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerBIRC7 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)BIRC7
dbVarBIRC7
ClinVarBIRC7
1000_GenomesBIRC7 
Exome Variant ServerBIRC7
ExAC (Exome Aggregation Consortium)ENSG00000101197
GNOMAD BrowserENSG00000101197
Varsome BrowserBIRC7
Genetic variants : HAPMAP79444
Genomic Variants (DGV)BIRC7 [DGVbeta]
DECIPHERBIRC7 [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisBIRC7 
Mutations
ICGC Data PortalBIRC7 
TCGA Data PortalBIRC7 
Broad Tumor PortalBIRC7
OASIS PortalBIRC7 [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICBIRC7  [overview]  [genome browser]  [tissue]  [distribution]  
Mutations and Diseases : HGMDBIRC7
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD - Leiden Open Variation Database
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
BioMutasearch BIRC7
DgiDB (Drug Gene Interaction Database)BIRC7
DoCM (Curated mutations)BIRC7 (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)BIRC7 (select a term)
intoGenBIRC7
Cancer3DBIRC7(select the gene name)
Impact of mutations[PolyPhen2] [Provean] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM605737   
Orphanet
DisGeNETBIRC7
MedgenBIRC7
Genetic Testing Registry BIRC7
NextProtQ96CA5 [Medical]
TSGene79444
GENETestsBIRC7
Target ValidationBIRC7
Huge Navigator BIRC7 [HugePedia]
snp3D : Map Gene to Disease79444
BioCentury BCIQBIRC7
ClinGenBIRC7
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD79444
Chemical/Pharm GKB GenePA25364
Clinical trialBIRC7
Miscellaneous
canSAR (ICR)BIRC7 (select the gene name)
Probes
Litterature
PubMed124 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineBIRC7
EVEXBIRC7
GoPubMedBIRC7
iHOPBIRC7
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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indexed on : Tue Nov 6 10:54:08 CET 2018

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