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BMP8A (bone morphogenetic protein 8a)

Identity

Other alias-
HGNC (Hugo) BMP8A
LocusID (NCBI) 353500
Atlas_Id 54986
Location 1p34.3  [Link to chromosome band 1p34]
Location_base_pair Starts at 39491646 and ends at 39529869 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2016)
BMP8A (1p34.3) / PPIEL (1p34.3)

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


External links

Nomenclature
HGNC (Hugo)BMP8A   21650
Cards
Entrez_Gene (NCBI)BMP8A  353500  bone morphogenetic protein 8a
Aliases
GeneCards (Weizmann)BMP8A
Ensembl hg19 (Hinxton)ENSG00000183682 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000183682 [Gene_View]  chr1:39491646-39529869 [Contig_View]  BMP8A [Vega]
ICGC DataPortalENSG00000183682
TCGA cBioPortalBMP8A
AceView (NCBI)BMP8A
Genatlas (Paris)BMP8A
WikiGenes353500
SOURCE (Princeton)BMP8A
Genetics Home Reference (NIH)BMP8A
Genomic and cartography
GoldenPath hg38 (UCSC)BMP8A  -     chr1:39491646-39529869 +  1p34.3   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)BMP8A  -     1p34.3   [Description]    (hg19-Feb_2009)
EnsemblBMP8A - 1p34.3 [CytoView hg19]  BMP8A - 1p34.3 [CytoView hg38]
Mapping of homologs : NCBIBMP8A [Mapview hg19]  BMP8A [Mapview hg38]
Gene and transcription
Genbank (Entrez)AA732526 AK024413 AK127199 AY303954 BC093743
RefSeq transcript (Entrez)NM_181809
RefSeq genomic (Entrez)
Consensus coding sequences : CCDS (NCBI)BMP8A
Cluster EST : UnigeneHs.472497 [ NCBI ]
CGAP (NCI)Hs.472497
Alternative Splicing GalleryENSG00000183682
Gene ExpressionBMP8A [ NCBI-GEO ]   BMP8A [ EBI - ARRAY_EXPRESS ]   BMP8A [ SEEK ]   BMP8A [ MEM ]
Gene Expression Viewer (FireBrowse)BMP8A [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevisibleExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)353500
GTEX Portal (Tissue expression)BMP8A
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ7Z5Y6   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtQ7Z5Y6  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProQ7Z5Y6
Splice isoforms : SwissVarQ7Z5Y6
PhosPhoSitePlusQ7Z5Y6
Domaine pattern : Prosite (Expaxy)TGF_BETA_1 (PS00250)    TGF_BETA_2 (PS51362)   
Domains : Interpro (EBI)Cystine-knot_cytokine    TGF-b_C    TGF-b_propeptide    TGF-beta-rel    TGFb_CS   
Domain families : Pfam (Sanger)TGF_beta (PF00019)    TGFb_propeptide (PF00688)   
Domain families : Pfam (NCBI)pfam00019    pfam00688   
Domain families : Smart (EMBL)TGFB (SM00204)  
Conserved Domain (NCBI)BMP8A
DMDM Disease mutations353500
Blocks (Seattle)BMP8A
SuperfamilyQ7Z5Y6
Human Protein AtlasENSG00000183682
Peptide AtlasQ7Z5Y6
HPRD16555
IPIIPI00376235   IPI00015451   
Protein Interaction databases
DIP (DOE-UCLA)Q7Z5Y6
IntAct (EBI)Q7Z5Y6
FunCoupENSG00000183682
BioGRIDBMP8A
STRING (EMBL)BMP8A
ZODIACBMP8A
Ontologies - Pathways
QuickGOQ7Z5Y6
Ontology : AmiGOossification  diet induced thermogenesis  cytokine activity  transforming growth factor beta receptor binding  extracellular space  growth factor activity  positive regulation of pathway-restricted SMAD protein phosphorylation  BMP signaling pathway  regulation of apoptotic process  regulation of MAPK cascade  negative regulation of insulin secretion  cell development  cartilage development  SMAD protein signal transduction  BMP receptor binding  regulation of energy homeostasis  
Ontology : EGO-EBIossification  diet induced thermogenesis  cytokine activity  transforming growth factor beta receptor binding  extracellular space  growth factor activity  positive regulation of pathway-restricted SMAD protein phosphorylation  BMP signaling pathway  regulation of apoptotic process  regulation of MAPK cascade  negative regulation of insulin secretion  cell development  cartilage development  SMAD protein signal transduction  BMP receptor binding  regulation of energy homeostasis  
Pathways : KEGGTGF-beta signaling pathway    Hippo signaling pathway   
NDEx NetworkBMP8A
Atlas of Cancer Signalling NetworkBMP8A
Wikipedia pathwaysBMP8A
Orthology - Evolution
OrthoDB353500
GeneTree (enSembl)ENSG00000183682
Phylogenetic Trees/Animal Genes : TreeFamBMP8A
HOVERGENQ7Z5Y6
HOGENOMQ7Z5Y6
Homologs : HomoloGeneBMP8A
Homology/Alignments : Family Browser (UCSC)BMP8A
Gene fusions - Rearrangements
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerBMP8A [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)BMP8A
dbVarBMP8A
ClinVarBMP8A
1000_GenomesBMP8A 
Exome Variant ServerBMP8A
ExAC (Exome Aggregation Consortium)BMP8A (select the gene name)
Genetic variants : HAPMAP353500
Genomic Variants (DGV)BMP8A [DGVbeta]
DECIPHERBMP8A [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisBMP8A 
Mutations
ICGC Data PortalBMP8A 
TCGA Data PortalBMP8A 
Broad Tumor PortalBMP8A
OASIS PortalBMP8A [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICBMP8A  [overview]  [genome browser]  [tissue]  [distribution]  
Mutations and Diseases : HGMDBMP8A
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD - Leiden Open Variation Database
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
BioMutasearch BMP8A
DgiDB (Drug Gene Interaction Database)BMP8A
DoCM (Curated mutations)BMP8A (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)BMP8A (select a term)
intoGenBMP8A
Cancer3DBMP8A(select the gene name)
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM
Orphanet
MedgenBMP8A
Genetic Testing Registry BMP8A
NextProtQ7Z5Y6 [Medical]
TSGene353500
GENETestsBMP8A
Target ValidationBMP8A
Huge Navigator BMP8A [HugePedia]
snp3D : Map Gene to Disease353500
BioCentury BCIQBMP8A
ClinGenBMP8A
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD353500
Chemical/Pharm GKB GenePA134894231
Clinical trialBMP8A
Miscellaneous
canSAR (ICR)BMP8A (select the gene name)
Probes
Litterature
PubMed15 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineBMP8A
EVEXBMP8A
GoPubMedBMP8A
iHOPBMP8A
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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indexed on : Mon Sep 25 18:59:23 CEST 2017

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