Atlas of Genetics and Cytogenetics in Oncology and Haematology


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BMX (BMX non-receptor tyrosine kinase)

Identity

Alias_symbol (synonym)ETK
PSCTK3
Other aliasPSCTK2
HGNC (Hugo) BMX
LocusID (NCBI) 660
Atlas_Id 819
Location Xp22.2  [Link to chromosome band Xp22]
Location_base_pair Starts at 15500777 and ends at 15556529 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2016)
BMX (Xp22.2) / BMX (Xp22.2)

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


External links

Nomenclature
HGNC (Hugo)BMX   1079
Cards
Entrez_Gene (NCBI)BMX  660  BMX non-receptor tyrosine kinase
AliasesETK; PSCTK2; PSCTK3
GeneCards (Weizmann)BMX
Ensembl hg19 (Hinxton)ENSG00000102010 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000102010 [Gene_View]  chrX:15500777-15556529 [Contig_View]  BMX [Vega]
ICGC DataPortalENSG00000102010
TCGA cBioPortalBMX
AceView (NCBI)BMX
Genatlas (Paris)BMX
WikiGenes660
SOURCE (Princeton)BMX
Genetics Home Reference (NIH)BMX
Genomic and cartography
GoldenPath hg38 (UCSC)BMX  -     chrX:15500777-15556529 +  Xp22.2   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)BMX  -     Xp22.2   [Description]    (hg19-Feb_2009)
EnsemblBMX - Xp22.2 [CytoView hg19]  BMX - Xp22.2 [CytoView hg38]
Mapping of homologs : NCBIBMX [Mapview hg19]  BMX [Mapview hg38]
OMIM300101   
Gene and transcription
Genbank (Entrez)AF045459 AK291824 AK313568 BC016652 BP236451
RefSeq transcript (Entrez)NM_001320866 NM_001721 NM_203281
RefSeq genomic (Entrez)
Consensus coding sequences : CCDS (NCBI)BMX
Cluster EST : UnigeneHs.495731 [ NCBI ]
CGAP (NCI)Hs.495731
Alternative Splicing GalleryENSG00000102010
Gene ExpressionBMX [ NCBI-GEO ]   BMX [ EBI - ARRAY_EXPRESS ]   BMX [ SEEK ]   BMX [ MEM ]
Gene Expression Viewer (FireBrowse)BMX [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevisibleExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)660
GTEX Portal (Tissue expression)BMX
Protein : pattern, domain, 3D structure
UniProt/SwissProtP51813   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtP51813  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProP51813
Splice isoforms : SwissVarP51813
Catalytic activity : Enzyme2.7.10.2 [ Enzyme-Expasy ]   2.7.10.22.7.10.2 [ IntEnz-EBI ]   2.7.10.2 [ BRENDA ]   2.7.10.2 [ KEGG ]   
PhosPhoSitePlusP51813
Domaine pattern : Prosite (Expaxy)PH_DOMAIN (PS50003)    PROTEIN_KINASE_ATP (PS00107)    PROTEIN_KINASE_DOM (PS50011)    PROTEIN_KINASE_TYR (PS00109)    SH2 (PS50001)    ZF_BTK (PS51113)   
Domains : Interpro (EBI)BMX    Kinase-like_dom    PH_dom-like    PH_domain    Prot_kinase_dom    Protein_kinase_ATP_BS    Ser-Thr/Tyr_kinase_cat_dom    SH2    Tyr_kinase_AS    Tyr_kinase_cat_dom    Znf_Btk_motif   
Domain families : Pfam (Sanger)BTK (PF00779)    PH (PF00169)    Pkinase_Tyr (PF07714)    SH2 (PF00017)   
Domain families : Pfam (NCBI)pfam00779    pfam00169    pfam07714    pfam00017   
Domain families : Smart (EMBL)BTK (SM00107)  PH (SM00233)  SH2 (SM00252)  TyrKc (SM00219)  
Conserved Domain (NCBI)BMX
DMDM Disease mutations660
Blocks (Seattle)BMX
PDB (SRS)2EKX    2YS2    3SXR    3SXS   
PDB (PDBSum)2EKX    2YS2    3SXR    3SXS   
PDB (IMB)2EKX    2YS2    3SXR    3SXS   
PDB (RSDB)2EKX    2YS2    3SXR    3SXS   
Structural Biology KnowledgeBase2EKX    2YS2    3SXR    3SXS   
SCOP (Structural Classification of Proteins)2EKX    2YS2    3SXR    3SXS   
CATH (Classification of proteins structures)2EKX    2YS2    3SXR    3SXS   
SuperfamilyP51813
Human Protein AtlasENSG00000102010
Peptide AtlasP51813
HPRD02111
IPIIPI00020899   
Protein Interaction databases
DIP (DOE-UCLA)P51813
IntAct (EBI)P51813
FunCoupENSG00000102010
BioGRIDBMX
STRING (EMBL)BMX
ZODIACBMX
Ontologies - Pathways
QuickGOP51813
Ontology : AmiGONK T cell differentiation  protein tyrosine kinase activity  non-membrane spanning protein tyrosine kinase activity  non-membrane spanning protein tyrosine kinase activity  signal transducer activity  receptor binding  protein binding  ATP binding  nucleoplasm  cytosol  plasma membrane  protein phosphorylation  phosphatidylinositol biosynthetic process  cell adhesion  signal transduction  transmembrane receptor protein tyrosine kinase signaling pathway  mesoderm development  extrinsic component of cytoplasmic side of plasma membrane  ruffle membrane  intracellular signal transduction  peptidyl-tyrosine autophosphorylation  regulation of cell proliferation  innate immune response  protein autophosphorylation  metal ion binding  execution phase of apoptosis  
Ontology : EGO-EBINK T cell differentiation  protein tyrosine kinase activity  non-membrane spanning protein tyrosine kinase activity  non-membrane spanning protein tyrosine kinase activity  signal transducer activity  receptor binding  protein binding  ATP binding  nucleoplasm  cytosol  plasma membrane  protein phosphorylation  phosphatidylinositol biosynthetic process  cell adhesion  signal transduction  transmembrane receptor protein tyrosine kinase signaling pathway  mesoderm development  extrinsic component of cytoplasmic side of plasma membrane  ruffle membrane  intracellular signal transduction  peptidyl-tyrosine autophosphorylation  regulation of cell proliferation  innate immune response  protein autophosphorylation  metal ion binding  execution phase of apoptosis  
NDEx NetworkBMX
Atlas of Cancer Signalling NetworkBMX
Wikipedia pathwaysBMX
Orthology - Evolution
OrthoDB660
GeneTree (enSembl)ENSG00000102010
Phylogenetic Trees/Animal Genes : TreeFamBMX
HOVERGENP51813
HOGENOMP51813
Homologs : HomoloGeneBMX
Homology/Alignments : Family Browser (UCSC)BMX
Gene fusions - Rearrangements
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerBMX [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)BMX
dbVarBMX
ClinVarBMX
1000_GenomesBMX 
Exome Variant ServerBMX
ExAC (Exome Aggregation Consortium)BMX (select the gene name)
Genetic variants : HAPMAP660
Genomic Variants (DGV)BMX [DGVbeta]
DECIPHERBMX [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisBMX 
Mutations
ICGC Data PortalBMX 
TCGA Data PortalBMX 
Broad Tumor PortalBMX
OASIS PortalBMX [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICBMX  [overview]  [genome browser]  [tissue]  [distribution]  
Mutations and Diseases : HGMDBMX
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD - Leiden Open Variation Database
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
LOVD (Leiden Open Variation Database)X-chromosome gene database
BioMutasearch BMX
DgiDB (Drug Gene Interaction Database)BMX
DoCM (Curated mutations)BMX (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)BMX (select a term)
intoGenBMX
Cancer3DBMX(select the gene name)
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM300101   
Orphanet
MedgenBMX
Genetic Testing Registry BMX
NextProtP51813 [Medical]
TSGene660
GENETestsBMX
Target ValidationBMX
Huge Navigator BMX [HugePedia]
snp3D : Map Gene to Disease660
BioCentury BCIQBMX
ClinGenBMX
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD660
Chemical/Pharm GKB GenePA25389
Clinical trialBMX
Miscellaneous
canSAR (ICR)BMX (select the gene name)
Probes
Litterature
PubMed65 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineBMX
EVEXBMX
GoPubMedBMX
iHOPBMX
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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indexed on : Mon Sep 18 13:48:03 CEST 2017

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