BNC1 (basonuclin 1)

2016-10-01 Affiliation

Identity

HGNC

BNC1

LOCATION

15q25.2

LOCUSID

646

ALIAS

BNC,BSN1,HsT19447,POF16

Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, contribute in submission tool

Other Information

Locus ID:

NCBI: 646
MIM: 601930
HGNC: 1081
Ensembl: ENSG00000169594

Variants:

dbSNP: 646
ClinVar: 646
TCGA: ENSG00000169594
COSMIC: BNC1

RNA/Proteins

Gene ID	Transcript ID	Uniprot
ENSG00000169594	ENST00000345382	Q01954
ENSG00000169594	ENST00000569704	F5GY04

Expression (GTEx)

Adipose - Subcutaneous

Adipose - Visceral

Adrenal Gland

Artery - Aorta

Artery - Tibial

Bladder

Brain - Amygdala

Brain - Anterior cingulate cortex

Brain - Caudate

Brain - Cerebellar Hemisphere

Brain - Cerebellum

Brain - Cortex

Brain - Frontal Cortex

Brain - Hippocampus

Brain - Hypothalamus

Brain - Nucleus accumbens

Brain - Putamen

Brain - Spinal cord

Brain - Substantia nigra

Breast - Mammary Tissue

Cells - Cultured fibroblasts

Cells - EBV - transformed lymphocytes

Cervix - Ectocervix

Cervix - Endocervix

Colon - Sigmoid

Colon - Transverse

Esophagus - Gastroesophageal Junction

Esophagus - Mucosa

Esophagus - Muscularis

Fallopian Tube

Heart - Atrial Appendage

Heart - Left Ventricle

Kidney - Cortex

Kidney - Medulla

Liver

Lung

Minor Salivary Gland

Muscle - Skeletal

Nerve - Tibial

Ovary

Pancreas

Pituitary

Prostate

Skin - Not Sun Exposed

Skin - Sun Exposed

Small Intestine - Terminal Ileum

Spleen

Stomach

Testis

Thyroid

Uterus

Vagina

Whole Blood

References

Pubmed ID	Year	Title	Citations
16891417	2006	Basonuclins 1 and 2, whose genes share a common origin, are proteins with widely different properties and functions.	19
21741828	2012	p63 Transcriptionally regulates BNC1, a Pol I and Pol II transcription factor that regulates ribosomal biogenesis and epithelial differentiation.	5
30010909	2018	Basonuclin 1 deficiency is a cause of primary ovarian insufficiency.	5
24662832	2015	Basonuclin-1 modulates epithelial plasticity and TGF-β1-induced loss of epithelial cell integrity.	3
26821013	2016	Decreased Expression of BNC1 and BNC2 Is Associated with Genetic or Epigenetic Regulation in Hepatocellular Carcinoma.	2

Citation

Dessen P

BNC1 (basonuclin 1)

Atlas Genet Cytogenet Oncol Haematol. 2016-10-01

Online version: http://atlasgeneticsoncology.org/gene/56128/bnc1