Atlas of Genetics and Cytogenetics in Oncology and Haematology


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BPIFA1 (BPI fold containing family A member 1)

Identity

Alias_namesPLUNC
palate, lung and nasal epithelium carcinoma associated
palate, lung and nasal epithelium associated
Alias_symbol (synonym)LUNX
bA49G10.5
SPLUNC1
Other aliasNASG
SPURT
HGNC (Hugo) BPIFA1
LocusID (NCBI) 51297
Atlas_Id 52329
Location 20q11.21  [Link to chromosome band 20q11]
Location_base_pair Starts at 31823802 and ends at 31831115 bp from pter ( according to hg19-Feb_2009)
Fusion genes
(updated 2016)
BPIFA1 (20q11.21) / CLDN7 (17p13.1)RANBP10 (16q22.1) / BPIFA1 (20q11.21)BPIFA1 20q11.21 / CLDN7 17p13.1

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


External links

Nomenclature
HGNC (Hugo)BPIFA1   15749
Cards
Entrez_Gene (NCBI)BPIFA1  51297  BPI fold containing family A member 1
AliasesLUNX; NASG; PLUNC; SPLUNC1; 
SPURT; bA49G10.5
GeneCards (Weizmann)BPIFA1
Ensembl hg19 (Hinxton)ENSG00000198183 [Gene_View]  chr20:31823802-31831115 [Contig_View]  BPIFA1 [Vega]
Ensembl hg38 (Hinxton)ENSG00000198183 [Gene_View]  chr20:31823802-31831115 [Contig_View]  BPIFA1 [Vega]
ICGC DataPortalENSG00000198183
TCGA cBioPortalBPIFA1
AceView (NCBI)BPIFA1
Genatlas (Paris)BPIFA1
WikiGenes51297
SOURCE (Princeton)BPIFA1
Genetics Home Reference (NIH)BPIFA1
Genomic and cartography
GoldenPath hg19 (UCSC)BPIFA1  -     chr20:31823802-31831115 +  20q11.21   [Description]    (hg19-Feb_2009)
GoldenPath hg38 (UCSC)BPIFA1  -     20q11.21   [Description]    (hg38-Dec_2013)
EnsemblBPIFA1 - 20q11.21 [CytoView hg19]  BPIFA1 - 20q11.21 [CytoView hg38]
Mapping of homologs : NCBIBPIFA1 [Mapview hg19]  BPIFA1 [Mapview hg38]
OMIM607412   
Gene and transcription
Genbank (Entrez)AB024937 AF158745 AF172993 AF417256 AF417257
RefSeq transcript (Entrez)NM_001243193 NM_016583 NM_130852
RefSeq genomic (Entrez)NC_000020 NC_018931 NT_011362 NW_004929418
Consensus coding sequences : CCDS (NCBI)BPIFA1
Cluster EST : UnigeneHs.211092 [ NCBI ]
CGAP (NCI)Hs.211092
Alternative Splicing GalleryENSG00000198183
Gene ExpressionBPIFA1 [ NCBI-GEO ]   BPIFA1 [ EBI - ARRAY_EXPRESS ]   BPIFA1 [ SEEK ]   BPIFA1 [ MEM ]
Gene Expression Viewer (FireBrowse)BPIFA1 [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevisibleExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)51297
GTEX Portal (Tissue expression)BPIFA1
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ9NP55   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtQ9NP55  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProQ9NP55
Splice isoforms : SwissVarQ9NP55
PhosPhoSitePlusQ9NP55
Domains : Interpro (EBI)Bactericidal_perm-incr_a/b_dom    BPI/LBP/Plunc    BPIFA1/Latherin    Lipid-bd_serum_glycop_N   
Domain families : Pfam (Sanger)LBP_BPI_CETP (PF01273)   
Domain families : Pfam (NCBI)pfam01273   
Conserved Domain (NCBI)BPIFA1
DMDM Disease mutations51297
Blocks (Seattle)BPIFA1
PDB (SRS)4KEG    4KGH    4KGO    4N4X   
PDB (PDBSum)4KEG    4KGH    4KGO    4N4X   
PDB (IMB)4KEG    4KGH    4KGO    4N4X   
PDB (RSDB)4KEG    4KGH    4KGO    4N4X   
Structural Biology KnowledgeBase4KEG    4KGH    4KGO    4N4X   
SCOP (Structural Classification of Proteins)4KEG    4KGH    4KGO    4N4X   
CATH (Classification of proteins structures)4KEG    4KGH    4KGO    4N4X   
SuperfamilyQ9NP55
Human Protein AtlasENSG00000198183
Peptide AtlasQ9NP55
HPRD07594
IPIIPI00009856   IPI01011238   
Protein Interaction databases
DIP (DOE-UCLA)Q9NP55
IntAct (EBI)Q9NP55
FunCoupENSG00000198183
BioGRIDBPIFA1
STRING (EMBL)BPIFA1
ZODIACBPIFA1
Ontologies - Pathways
QuickGOQ9NP55
Ontology : AmiGOmolecular_function  protein binding  extracellular region  extracellular space  lipid binding  antibacterial humoral response  innate immune response  innate immune response  regulation of liquid surface tension  multicellular organismal water homeostasis  negative regulation of single-species biofilm formation in or on host organism  regulation of sodium ion transmembrane transport  
Ontology : EGO-EBImolecular_function  protein binding  extracellular region  extracellular space  lipid binding  antibacterial humoral response  innate immune response  innate immune response  regulation of liquid surface tension  multicellular organismal water homeostasis  negative regulation of single-species biofilm formation in or on host organism  regulation of sodium ion transmembrane transport  
NDEx NetworkBPIFA1
Atlas of Cancer Signalling NetworkBPIFA1
Wikipedia pathwaysBPIFA1
Orthology - Evolution
OrthoDB51297
GeneTree (enSembl)ENSG00000198183
Phylogenetic Trees/Animal Genes : TreeFamBPIFA1
HOVERGENQ9NP55
HOGENOMQ9NP55
Homologs : HomoloGeneBPIFA1
Homology/Alignments : Family Browser (UCSC)BPIFA1
Gene fusions - Rearrangements
Fusion : MitelmanBPIFA1/CLDN7 [20q11.21/17p13.1]  
Fusion: TCGABPIFA1 20q11.21 CLDN7 17p13.1 LUAD
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerBPIFA1 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)BPIFA1
dbVarBPIFA1
ClinVarBPIFA1
1000_GenomesBPIFA1 
Exome Variant ServerBPIFA1
ExAC (Exome Aggregation Consortium)BPIFA1 (select the gene name)
Genetic variants : HAPMAP51297
Genomic Variants (DGV)BPIFA1 [DGVbeta]
DECIPHER (Syndromes)20:31823802-31831115  ENSG00000198183
CONAN: Copy Number AnalysisBPIFA1 
Mutations
ICGC Data PortalBPIFA1 
TCGA Data PortalBPIFA1 
Broad Tumor PortalBPIFA1
OASIS PortalBPIFA1 [ Somatic mutations - Copy number]
Mutations and Diseases : HGMDBPIFA1
BioMutasearch BPIFA1
DgiDB (Drug Gene Interaction Database)BPIFA1
DoCM (Curated mutations)BPIFA1 (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)BPIFA1 (select a term)
intoGenBPIFA1
Cancer3DBPIFA1(select the gene name)
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM607412   
Orphanet
MedgenBPIFA1
Genetic Testing Registry BPIFA1
NextProtQ9NP55 [Medical]
TSGene51297
GENETestsBPIFA1
Huge Navigator BPIFA1 [HugePedia]
snp3D : Map Gene to Disease51297
BioCentury BCIQBPIFA1
ClinGenBPIFA1
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD51297
Chemical/Pharm GKB GenePA33423
Clinical trialBPIFA1
Miscellaneous
canSAR (ICR)BPIFA1 (select the gene name)
Probes
Litterature
PubMed71 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineBPIFA1
EVEXBPIFA1
GoPubMedBPIFA1
iHOPBPIFA1
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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indexed on : Tue Mar 14 12:57:45 CET 2017

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