BPTF (bromodomain PHD finger transcription factor)

2003-02-01  

Identity

HGNC
LOCATION
17q24.2
LOCUSID
ALIAS
FAC1,FALZ,NEDDFL,NURF301
FUSION GENES

Other Information

Locus ID:

NCBI: 2186
MIM: 601819
HGNC: 3581
Ensembl: ENSG00000171634

Variants:

dbSNP: 2186
ClinVar: 2186
TCGA: ENSG00000171634
COSMIC: BPTF

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000171634ENST00000306378Q12830
ENSG00000171634ENST00000321892Q12830
ENSG00000171634ENST00000335221A0A0A0MR81
ENSG00000171634ENST00000342579E9PE19
ENSG00000171634ENST00000424123E7ETD6
ENSG00000171634ENST00000544491F5H176
ENSG00000171634ENST00000544778F5GXF5
ENSG00000171634ENST00000577837J3KSY0
ENSG00000171634ENST00000580465J3KSK9
ENSG00000171634ENST00000581258J3QQQ8
ENSG00000171634ENST00000582467J3QQK4
ENSG00000171634ENST00000583990J3QLW4
ENSG00000171634ENST00000644067A0A2R8Y7Q1

Expression (GTEx)

0
5
10
15
20
25
30
35
40

Protein levels (Protein atlas)

Not detected
Low
Medium
High

References

Pubmed IDYearTitleCitations
167289782006Molecular basis for site-specific read-out of histone H3K4me3 by the BPTF PHD finger of NURF.302
215964262011Recognition of a mononucleosomal histone modification pattern by BPTF via multivalent interactions.150
191901322009The expression of three genes in primary non-small cell lung cancer is associated with metastatic spread to the brain.60
309224022019Circular RNA circ-DONSON facilitates gastric cancer growth and invasion via NURF complex dependent activation of transcription factor SOX4.30
203001782010A novel translocation breakpoint within the BPTF gene is associated with a pre-malignant phenotype.24
264188992015BPTF promotes tumor growth and predicts poor prognosis in lung adenocarcinomas.20
257166922015The prognostic significance of bromodomain PHD-finger transcription factor in colorectal carcinoma and association with vimentin and E-cadherin.19
280253292017Association between GWAS-identified lung adenocarcinoma susceptibility loci and EGFR mutations in never-smoking Asian women, and comparison with findings from Western populations.13
289429662017Haploinsufficiency of the Chromatin Remodeler BPTF Causes Syndromic Developmental and Speech Delay, Postnatal Microcephaly, and Dysmorphic Features.12
153795502004Fetal Alz-50 clone 1 interacts with the human orthologue of the Kelch-like Ech-associated protein.11

Citation

Dessen P

BPTF (bromodomain PHD finger transcription factor)

Atlas Genet Cytogenet Oncol Haematol. 2003-02-01

Online version: http://atlasgeneticsoncology.org/gene/40526/bptf