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BRD1 (bromodomain containing 1)

Identity

Other namesBRL
BRPF1
BRPF2
HGNC (Hugo) BRD1
LocusID (NCBI) 23774
Location 22q13.33
Location_base_pair Starts at 50166937 and ends at 50218452 bp from pter ( according to hg19-Feb_2009)
Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 

Protein

 

Other Leukemias implicated (Data extracted from papers in the Atlas)

Leukemias t0817q24q22ID1494

External links

Nomenclature
HGNC (Hugo)BRD1   1102
Cards
Entrez_Gene (NCBI)BRD1  23774  bromodomain containing 1
GeneCards (Weizmann)BRD1
Ensembl (Hinxton)ENSG00000100425 [Gene_View]  chr22:50166937-50218452 [Contig_View]  BRD1 [Vega]
ICGC DataPortalENSG00000100425
cBioPortalBRD1
AceView (NCBI)BRD1
Genatlas (Paris)BRD1
WikiGenes23774
SOURCE (Princeton)NM_014577
Genomic and cartography
GoldenPath (UCSC)BRD1  -  22q13.33   chr22:50166937-50218452 -  22q13.33   [Description]    (hg19-Feb_2009)
EnsemblBRD1 - 22q13.33 [CytoView]
Mapping of homologs : NCBIBRD1 [Mapview]
OMIM604589   
Gene and transcription
Genbank (Entrez)AB209216 AF005067 AK292428 AK302736 AK302845
RefSeq transcript (Entrez)NM_014577
RefSeq genomic (Entrez)AC_000154 NC_000022 NC_018933 NT_011520 NW_001838754 NW_004929430
Consensus coding sequences : CCDS (NCBI)BRD1
Cluster EST : UnigeneHs.127950 [ NCBI ]
CGAP (NCI)Hs.127950
Alternative Splicing : Fast-db (Paris)GSHG0020504
Alternative Splicing GalleryENSG00000100425
Gene ExpressionBRD1 [ NCBI-GEO ]     BRD1 [ SEEK ]   BRD1 [ MEM ]
Protein : pattern, domain, 3D structure
UniProt/SwissProtO95696 (Uniprot)
NextProtO95696  [Medical]
With graphics : InterProO95696
Splice isoforms : SwissVarO95696 (Swissvar)
Domaine pattern : Prosite (Expaxy)BROMODOMAIN_1 (PS00633)    BROMODOMAIN_2 (PS50014)    PWWP (PS50812)    ZF_PHD_1 (PS01359)    ZF_PHD_2 (PS50016)   
Domains : Interpro (EBI)Bromodomain [organisation]   Bromodomain_CS [organisation]   Enhancer_polycomb-like_N [organisation]   PWWP_dom [organisation]   Zinc_finger_PHD-type_CS [organisation]   Znf_FYVE_PHD [organisation]   Znf_PHD [organisation]   Znf_PHD-finger [organisation]   Znf_RING/FYVE/PHD [organisation]  
Related proteins : CluSTrO95696
Domain families : Pfam (Sanger)Bromodomain (PF00439)    EPL1 (PF10513)    PWWP (PF00855)   
Domain families : Pfam (NCBI)pfam00439    pfam10513    pfam00855   
Domain families : Smart (EMBL)BROMO (SM00297)  PHD (SM00249)  PWWP (SM00293)  
DMDM Disease mutations23774
Blocks (Seattle)O95696
PDB (SRS)2KU3    2L43    2LQ6    3LYI    3RCW   
PDB (PDBSum)2KU3    2L43    2LQ6    3LYI    3RCW   
PDB (IMB)2KU3    2L43    2LQ6    3LYI    3RCW   
PDB (RSDB)2KU3    2L43    2LQ6    3LYI    3RCW   
Human Protein AtlasENSG00000100425 [gene] [tissue] [antibody] [cell] [cancer]
Peptide AtlasO95696
HPRD06848
IPIIPI00032214   IPI00384471   IPI00922474   IPI00941079   IPI01011372   IPI00556201   
Protein Interaction databases
DIP (DOE-UCLA)O95696
IntAct (EBI)O95696
FunCoupENSG00000100425
BioGRIDBRD1
InParanoidO95696
Interologous Interaction database O95696
IntegromeDBBRD1
STRING (EMBL)BRD1
Ontologies - Pathways
Ontology : AmiGOnucleus  nucleus  zinc ion binding  histone binding  histone H3 acetylation  MOZ/MORF histone acetyltransferase complex  
Ontology : EGO-EBInucleus  nucleus  zinc ion binding  histone binding  histone H3 acetylation  MOZ/MORF histone acetyltransferase complex  
Protein Interaction DatabaseBRD1
Wikipedia pathwaysBRD1
Gene fusion - rearrangments
Rearrangement : TICdbPAX5 [9p13.2]  -  BRD1 [3q27.3]
Polymorphisms : SNP, mutations, diseases
SNP Single Nucleotide Polymorphism (NCBI)BRD1
snp3D : Map Gene to Disease23774
SNP (GeneSNP Utah)BRD1
SNP : HGBaseBRD1
Genetic variants : HAPMAPBRD1
Exome VariantBRD1
1000_GenomesBRD1 
ICGC programENSG00000100425 
Somatic Mutations in Cancer : COSMICBRD1 
CONAN: Copy Number AnalysisBRD1 
Mutations and Diseases : HGMDBRD1
Genomic VariantsBRD1  BRD1 [DGVbeta]
dbVarBRD1
ClinVarBRD1
Pred. of missensesPolyPhen-2  SIFT(SG)  SIFT(JCVI)  Align-GVGD  MutAssessor  Mutanalyser  
Pred. splicesGeneSplicer  Human Splicing Finder  MaxEntScan  
Diseases
OMIM604589   
MedgenBRD1
GENETestsBRD1
Disease Genetic AssociationBRD1
Huge Navigator BRD1 [HugePedia]  BRD1 [HugeCancerGEM]
General knowledge
Homologs : HomoloGeneBRD1
Homology/Alignments : Family Browser (UCSC)BRD1
Phylogenetic Trees/Animal Genes : TreeFamBRD1
Chemical/Protein Interactions : CTD23774
Chemical/Pharm GKB GenePA25413
Clinical trialBRD1
Cancer Resource (Charite)ENSG00000100425
Other databases
Probes
Litterature
PubMed26 Pubmed reference(s) in Entrez
CoreMineBRD1
iHOPBRD1
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

Search in all EBI   NCBI

Contributor(s)

Written09-2002Dessen P, Le Minor S
Updated12-2013Dessen P

© Atlas of Genetics and Cytogenetics in Oncology and Haematology
indexed on : Fri Jul 11 16:46:34 CEST 2014

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