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BRD8 (bromodomain containing 8)

Identity

Alias (NCBI)SMAP
SMAP2
p120
HGNC (Hugo) BRD8
HGNC Alias symbSMAP
p120
LocusID (NCBI) 10902
Atlas_Id 51290
Location 5q31.2  [Link to chromosome band 5q31]
Location_base_pair Starts at 138139770 and ends at 138178630 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2017)
Data from Atlas, Mitelman, Cosmic Fusion, Fusion Cancer, TCGA fusion databases with official HUGO symbols (see references in chromosomal bands)
BRD8 (5q31.2) / HLA-DRA (6p21.32)BRD8 (5q31.2) / RBFOX1 (16p13.3)YME1L1 (10p12.1) / BRD8 (5q31.2)

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 



Other Solid tumors implicated (Data extracted from papers in the Atlas) [ 1 ]
  t(5;6)(q31;p21) BRD8/PHF1


External links

Nomenclature
HGNC (Hugo)BRD8   19874
Cards
Entrez_Gene (NCBI)BRD8  10902  bromodomain containing 8
AliasesSMAP; SMAP2; p120
GeneCards (Weizmann)BRD8
Ensembl hg19 (Hinxton)ENSG00000112983 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000112983 [Gene_View]  ENSG00000112983 [Sequence]  chr5:138139770-138178630 [Contig_View]  BRD8 [Vega]
ICGC DataPortalENSG00000112983
TCGA cBioPortalBRD8
AceView (NCBI)BRD8
Genatlas (Paris)BRD8
WikiGenes10902
SOURCE (Princeton)BRD8
Genetics Home Reference (NIH)BRD8
Genomic and cartography
GoldenPath hg38 (UCSC)BRD8  -     chr5:138139770-138178630 -  5q31.2   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)BRD8  -     5q31.2   [Description]    (hg19-Feb_2009)
GoldenPathBRD8 - 5q31.2 [CytoView hg19]  BRD8 - 5q31.2 [CytoView hg38]
ImmunoBaseENSG00000112983
genome Data Viewer NCBIBRD8 [Mapview hg19]  
OMIM602848   
Gene and transcription
Genbank (Entrez)AB209079 AF016270 AK124191 AK225928 AK289951
RefSeq transcript (Entrez)NM_001164326 NM_001300961 NM_001300962 NM_001300966 NM_006696 NM_139199 NM_183359
RefSeq genomic (Entrez)
Consensus coding sequences : CCDS (NCBI)BRD8
Alternative Splicing GalleryENSG00000112983
Gene ExpressionBRD8 [ NCBI-GEO ]   BRD8 [ EBI - ARRAY_EXPRESS ]   BRD8 [ SEEK ]   BRD8 [ MEM ]
Gene Expression Viewer (FireBrowse)BRD8 [ Firebrowse - Broad ]
GenevisibleExpression of BRD8 in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)10902
GTEX Portal (Tissue expression)BRD8
Human Protein AtlasENSG00000112983-BRD8 [pathology]   [cell]   [tissue]
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ9H0E9   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtQ9H0E9  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProQ9H0E9
Splice isoforms : SwissVarQ9H0E9
PhosPhoSitePlusQ9H0E9
Domaine pattern : Prosite (Expaxy)BROMODOMAIN_2 (PS50014)   
Domains : Interpro (EBI)BRD8    Brd8_Bromo_dom    Bromodomain    Bromodomain-like_sf   
Domain families : Pfam (Sanger)Bromodomain (PF00439)   
Domain families : Pfam (NCBI)pfam00439   
Domain families : Smart (EMBL)BROMO (SM00297)  
Conserved Domain (NCBI)BRD8
DMDM Disease mutations10902
Blocks (Seattle)BRD8
SuperfamilyQ9H0E9
Human Protein Atlas [tissue]ENSG00000112983-BRD8 [tissue]
Peptide AtlasQ9H0E9
HPRD04166
IPIIPI00019226   IPI00148057   IPI00016570   IPI00828194   IPI01013224   IPI00878545   IPI00878385   IPI00878882   IPI00878733   IPI00877831   IPI00877679   IPI00879787   IPI00879641   IPI00967544   IPI00964671   IPI00967280   
Protein Interaction databases
DIP (DOE-UCLA)Q9H0E9
IntAct (EBI)Q9H0E9
FunCoupENSG00000112983
BioGRIDBRD8
STRING (EMBL)BRD8
ZODIACBRD8
Ontologies - Pathways
QuickGOQ9H0E9
Ontology : AmiGOSwr1 complex  DNA-binding transcription factor activity  nuclear receptor activity  protein binding  nucleus  nucleoplasm  nucleoplasm  mitochondrion  regulation of transcription, DNA-templated  regulation of transcription by RNA polymerase II  signal transduction  cell surface receptor signaling pathway  histone acetylation  intracellular receptor signaling pathway  NuA4 histone acetyltransferase complex  NuA4 histone acetyltransferase complex  regulation of growth  histone H4 acetylation  histone H2A acetylation  positive regulation of transcription by RNA polymerase II  
Ontology : EGO-EBISwr1 complex  DNA-binding transcription factor activity  nuclear receptor activity  protein binding  nucleus  nucleoplasm  nucleoplasm  mitochondrion  regulation of transcription, DNA-templated  regulation of transcription by RNA polymerase II  signal transduction  cell surface receptor signaling pathway  histone acetylation  intracellular receptor signaling pathway  NuA4 histone acetyltransferase complex  NuA4 histone acetyltransferase complex  regulation of growth  histone H4 acetylation  histone H2A acetylation  positive regulation of transcription by RNA polymerase II  
NDEx NetworkBRD8
Atlas of Cancer Signalling NetworkBRD8
Wikipedia pathwaysBRD8
Orthology - Evolution
OrthoDB10902
GeneTree (enSembl)ENSG00000112983
Phylogenetic Trees/Animal Genes : TreeFamBRD8
HOGENOMQ9H0E9
Homologs : HomoloGeneBRD8
Homology/Alignments : Family Browser (UCSC)BRD8
Gene fusions - Rearrangements
Fusion : QuiverBRD8
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerBRD8 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)BRD8
dbVarBRD8
ClinVarBRD8
MonarchBRD8
1000_GenomesBRD8 
Exome Variant ServerBRD8
GNOMAD BrowserENSG00000112983
Varsome BrowserBRD8
Genetic variants : HAPMAP10902
Genomic Variants (DGV)BRD8 [DGVbeta]
DECIPHERBRD8 [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisBRD8 
Mutations
ICGC Data PortalBRD8 
TCGA Data PortalBRD8 
Broad Tumor PortalBRD8
OASIS PortalBRD8 [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICBRD8  [overview]  [genome browser]  [tissue]  [distribution]  
Somatic Mutations in Cancer : COSMIC3DBRD8
Mutations and Diseases : HGMDBRD8
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD - Leiden Open Variation Database
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
BioMutasearch BRD8
DgiDB (Drug Gene Interaction Database)BRD8
DoCM (Curated mutations)BRD8 (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)BRD8 (select a term)
intoGenBRD8
Cancer3DBRD8(select the gene name)
Impact of mutations[PolyPhen2] [Provean] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM602848   
Orphanet
DisGeNETBRD8
MedgenBRD8
Genetic Testing Registry BRD8
NextProtQ9H0E9 [Medical]
TSGene10902
GENETestsBRD8
Target ValidationBRD8
Huge Navigator BRD8 [HugePedia]
snp3D : Map Gene to Disease10902
BioCentury BCIQBRD8
ClinGenBRD8
Clinical trials, drugs, therapy
Protein Interactions : CTD10902
Pharm GKB GenePA134923194
Clinical trialBRD8
Miscellaneous
canSAR (ICR)BRD8 (select the gene name)
HarmonizomeBRD8
DataMed IndexBRD8
Probes
Litterature
PubMed54 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineBRD8
EVEXBRD8
GoPubMedBRD8
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

Search in all EBI   NCBI

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indexed on : Mon Sep 14 14:03:30 CEST 2020

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