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BRF2 (BRF2, RNA polymerase III transcription initiation factor 50 kDa subunit)

Identity

Alias_namesBRF2
Alias_symbol (synonym)FLJ11052
BRFU
TFIIIB50
Other alias
HGNC (Hugo) BRF2
LocusID (NCBI) 55290
Atlas_Id 50599
Location 8p11.23  [Link to chromosome band 8p11]
Location_base_pair Starts at 37701398 and ends at 37707431 bp from pter ( according to hg19-Feb_2009)
Fusion genes
(updated 2016)
RBMX (Xq26.3) / BRF2 (8p11.23)

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


External links

Nomenclature
HGNC (Hugo)BRF2   17298
Cards
Entrez_Gene (NCBI)BRF2  55290  BRF2, RNA polymerase III transcription initiation factor 50 kDa subunit
AliasesBRFU; TFIIIB50
GeneCards (Weizmann)BRF2
Ensembl hg19 (Hinxton)ENSG00000104221 [Gene_View]  chr8:37701398-37707431 [Contig_View]  BRF2 [Vega]
Ensembl hg38 (Hinxton)ENSG00000104221 [Gene_View]  chr8:37701398-37707431 [Contig_View]  BRF2 [Vega]
ICGC DataPortalENSG00000104221
TCGA cBioPortalBRF2
AceView (NCBI)BRF2
Genatlas (Paris)BRF2
WikiGenes55290
SOURCE (Princeton)BRF2
Genetics Home Reference (NIH)BRF2
Genomic and cartography
GoldenPath hg19 (UCSC)BRF2  -     chr8:37701398-37707431 -  8p11.23   [Description]    (hg19-Feb_2009)
GoldenPath hg38 (UCSC)BRF2  -     8p11.23   [Description]    (hg38-Dec_2013)
EnsemblBRF2 - 8p11.23 [CytoView hg19]  BRF2 - 8p11.23 [CytoView hg38]
Mapping of homologs : NCBIBRF2 [Mapview hg19]  BRF2 [Mapview hg38]
OMIM607013   
Gene and transcription
Genbank (Entrez)AA496239 AF130058 AF206673 AF298153 AK001914
RefSeq transcript (Entrez)NM_018310
RefSeq genomic (Entrez)NC_000008 NC_018919 NT_167187 NW_004929337
Consensus coding sequences : CCDS (NCBI)BRF2
Cluster EST : UnigeneHs.709301 [ NCBI ]
CGAP (NCI)Hs.709301
Alternative Splicing GalleryENSG00000104221
Gene ExpressionBRF2 [ NCBI-GEO ]   BRF2 [ EBI - ARRAY_EXPRESS ]   BRF2 [ SEEK ]   BRF2 [ MEM ]
Gene Expression Viewer (FireBrowse)BRF2 [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevisibleExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)55290
GTEX Portal (Tissue expression)BRF2
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ9HAW0   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtQ9HAW0  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProQ9HAW0
Splice isoforms : SwissVarQ9HAW0
PhosPhoSitePlusQ9HAW0
Domaine pattern : Prosite (Expaxy)ZF_TFIIB (PS51134)   
Domains : Interpro (EBI)Cyclin-like    TFIIB    Znf_TFIIB   
Domain families : Pfam (Sanger)TF_Zn_Ribbon (PF08271)   
Domain families : Pfam (NCBI)pfam08271   
Domain families : Smart (EMBL)CYCLIN (SM00385)  
Conserved Domain (NCBI)BRF2
DMDM Disease mutations55290
Blocks (Seattle)BRF2
PDB (SRS)4ROC    4ROD    4ROE   
PDB (PDBSum)4ROC    4ROD    4ROE   
PDB (IMB)4ROC    4ROD    4ROE   
PDB (RSDB)4ROC    4ROD    4ROE   
Structural Biology KnowledgeBase4ROC    4ROD    4ROE   
SCOP (Structural Classification of Proteins)4ROC    4ROD    4ROE   
CATH (Classification of proteins structures)4ROC    4ROD    4ROE   
SuperfamilyQ9HAW0
Human Protein AtlasENSG00000104221
Peptide AtlasQ9HAW0
HPRD06115
IPIIPI00301190   IPI01015606   IPI00797395   IPI01009536   
Protein Interaction databases
DIP (DOE-UCLA)Q9HAW0
IntAct (EBI)Q9HAW0
FunCoupENSG00000104221
BioGRIDBRF2
STRING (EMBL)BRF2
ZODIACBRF2
Ontologies - Pathways
QuickGOQ9HAW0
Ontology : AmiGOnucleoplasm  DNA-templated transcription, initiation  regulation of transcription, DNA-templated  zinc ion binding  
Ontology : EGO-EBInucleoplasm  DNA-templated transcription, initiation  regulation of transcription, DNA-templated  zinc ion binding  
NDEx NetworkBRF2
Atlas of Cancer Signalling NetworkBRF2
Wikipedia pathwaysBRF2
Orthology - Evolution
OrthoDB55290
GeneTree (enSembl)ENSG00000104221
Phylogenetic Trees/Animal Genes : TreeFamBRF2
HOVERGENQ9HAW0
HOGENOMQ9HAW0
Homologs : HomoloGeneBRF2
Homology/Alignments : Family Browser (UCSC)BRF2
Gene fusions - Rearrangements
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerBRF2 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)BRF2
dbVarBRF2
ClinVarBRF2
1000_GenomesBRF2 
Exome Variant ServerBRF2
ExAC (Exome Aggregation Consortium)BRF2 (select the gene name)
Genetic variants : HAPMAP55290
Genomic Variants (DGV)BRF2 [DGVbeta]
DECIPHER (Syndromes)8:37701398-37707431  ENSG00000104221
CONAN: Copy Number AnalysisBRF2 
Mutations
ICGC Data PortalBRF2 
TCGA Data PortalBRF2 
Broad Tumor PortalBRF2
OASIS PortalBRF2 [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICBRF2  [overview]  [genome browser]  [tissue]  [distribution]  
Mutations and Diseases : HGMDBRF2
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
BioMutasearch BRF2
DgiDB (Drug Gene Interaction Database)BRF2
DoCM (Curated mutations)BRF2 (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)BRF2 (select a term)
intoGenBRF2
Cancer3DBRF2(select the gene name)
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM607013   
Orphanet
MedgenBRF2
Genetic Testing Registry BRF2
NextProtQ9HAW0 [Medical]
TSGene55290
GENETestsBRF2
Huge Navigator BRF2 [HugePedia]
snp3D : Map Gene to Disease55290
BioCentury BCIQBRF2
ClinGenBRF2
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD55290
Chemical/Pharm GKB GenePA164741329
Clinical trialBRF2
Miscellaneous
canSAR (ICR)BRF2 (select the gene name)
Probes
Litterature
PubMed19 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineBRF2
EVEXBRF2
GoPubMedBRF2
iHOPBRF2
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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indexed on : Tue Mar 14 12:57:50 CET 2017

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