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BRPF1 (bromodomain and PHD finger containing 1)

Identity

Alias_namesbromodomain and PHD finger containing
Alias_symbol (synonym)BR140
Other aliasIDDDFP
HGNC (Hugo) BRPF1
LocusID (NCBI) 7862
Atlas_Id 844
Location 3p25.3  [Link to chromosome band 3p25]
Location_base_pair Starts at 9731750 and ends at 9748015 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2016)
BRPF1 (3p25.3) / AP3M1 (10q22.2)

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


Other Leukemias implicated (Data extracted from papers in the Atlas) [ 3 ]
  t(2;8)(p23;p11) KAT6A/ASXL2
t(9;22)(p13;q13) PAX5/BRD1
t(11;17)(q23;q12-21) KMT2A/MMLT6


External links

Nomenclature
HGNC (Hugo)BRPF1   14255
Cards
Entrez_Gene (NCBI)BRPF1  7862  bromodomain and PHD finger containing 1
AliasesBR140; IDDDFP
GeneCards (Weizmann)BRPF1
Ensembl hg19 (Hinxton)ENSG00000156983 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000156983 [Gene_View]  chr3:9731750-9748015 [Contig_View]  BRPF1 [Vega]
ICGC DataPortalENSG00000156983
TCGA cBioPortalBRPF1
AceView (NCBI)BRPF1
Genatlas (Paris)BRPF1
WikiGenes7862
SOURCE (Princeton)BRPF1
Genetics Home Reference (NIH)BRPF1
Genomic and cartography
GoldenPath hg38 (UCSC)BRPF1  -     chr3:9731750-9748015 +  3p25.3   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)BRPF1  -     3p25.3   [Description]    (hg19-Feb_2009)
EnsemblBRPF1 - 3p25.3 [CytoView hg19]  BRPF1 - 3p25.3 [CytoView hg38]
Mapping of homologs : NCBIBRPF1 [Mapview hg19]  BRPF1 [Mapview hg38]
OMIM602410   617333   
Gene and transcription
Genbank (Entrez)AI356310 AK293865 AL713696 BC036374 BC053851
RefSeq transcript (Entrez)NM_001003694 NM_001319049 NM_001319050 NM_004634
RefSeq genomic (Entrez)
Consensus coding sequences : CCDS (NCBI)BRPF1
Cluster EST : UnigeneHs.1004 [ NCBI ]
CGAP (NCI)Hs.1004
Alternative Splicing GalleryENSG00000156983
Gene ExpressionBRPF1 [ NCBI-GEO ]   BRPF1 [ EBI - ARRAY_EXPRESS ]   BRPF1 [ SEEK ]   BRPF1 [ MEM ]
Gene Expression Viewer (FireBrowse)BRPF1 [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevisibleExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)7862
GTEX Portal (Tissue expression)BRPF1
Protein : pattern, domain, 3D structure
UniProt/SwissProtP55201   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtP55201  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProP55201
Splice isoforms : SwissVarP55201
PhosPhoSitePlusP55201
Domaine pattern : Prosite (Expaxy)BROMODOMAIN_1 (PS00633)    BROMODOMAIN_2 (PS50014)    EPHD (PS51805)    PWWP (PS50812)    ZF_PHD_1 (PS01359)    ZF_PHD_2 (PS50016)    ZINC_FINGER_C2H2_1 (PS00028)    ZINC_FINGER_C2H2_2 (PS50157)   
Domains : Interpro (EBI)Bromodomain    Bromodomain_CS    Enhancer_polycomb-like_N    PWWP_dom    Zinc_finger_PHD-type_CS    Znf_C2H2    Znf_FYVE_PHD    Znf_PHD    Znf_PHD-finger    Znf_RING/FYVE/PHD   
Domain families : Pfam (Sanger)Bromodomain (PF00439)    EPL1 (PF10513)    PWWP (PF00855)   
Domain families : Pfam (NCBI)pfam00439    pfam10513    pfam00855   
Domain families : Smart (EMBL)BROMO (SM00297)  PHD (SM00249)  PWWP (SM00293)  
Conserved Domain (NCBI)BRPF1
DMDM Disease mutations7862
Blocks (Seattle)BRPF1
PDB (SRS)2D9E    2RS9    2X35    2X4W    2X4X    2X4Y    3L42    3MO8    4LC2    4QYD    4QYL    4UYE    5C6S    5C7N    5C85    5C87    5C89    5D7X    5DY7    5DYA    5DYC    5E3D    5E3G    5EM3    5EPR    5EPS    5EQ1    5ERC    5ETB    5ETD    5EV9    5EVA    5EWC    5EWD    5EWH    5EWV    5EWW    5FFV    5FFW    5FFY    5FG4    5FG5    5G4R    5G4S   
PDB (PDBSum)2D9E    2RS9    2X35    2X4W    2X4X    2X4Y    3L42    3MO8    4LC2    4QYD    4QYL    4UYE    5C6S    5C7N    5C85    5C87    5C89    5D7X    5DY7    5DYA    5DYC    5E3D    5E3G    5EM3    5EPR    5EPS    5EQ1    5ERC    5ETB    5ETD    5EV9    5EVA    5EWC    5EWD    5EWH    5EWV    5EWW    5FFV    5FFW    5FFY    5FG4    5FG5    5G4R    5G4S   
PDB (IMB)2D9E    2RS9    2X35    2X4W    2X4X    2X4Y    3L42    3MO8    4LC2    4QYD    4QYL    4UYE    5C6S    5C7N    5C85    5C87    5C89    5D7X    5DY7    5DYA    5DYC    5E3D    5E3G    5EM3    5EPR    5EPS    5EQ1    5ERC    5ETB    5ETD    5EV9    5EVA    5EWC    5EWD    5EWH    5EWV    5EWW    5FFV    5FFW    5FFY    5FG4    5FG5    5G4R    5G4S   
PDB (RSDB)2D9E    2RS9    2X35    2X4W    2X4X    2X4Y    3L42    3MO8    4LC2    4QYD    4QYL    4UYE    5C6S    5C7N    5C85    5C87    5C89    5D7X    5DY7    5DYA    5DYC    5E3D    5E3G    5EM3    5EPR    5EPS    5EQ1    5ERC    5ETB    5ETD    5EV9    5EVA    5EWC    5EWD    5EWH    5EWV    5EWW    5FFV    5FFW    5FFY    5FG4    5FG5    5G4R    5G4S   
Structural Biology KnowledgeBase2D9E    2RS9    2X35    2X4W    2X4X    2X4Y    3L42    3MO8    4LC2    4QYD    4QYL    4UYE    5C6S    5C7N    5C85    5C87    5C89    5D7X    5DY7    5DYA    5DYC    5E3D    5E3G    5EM3    5EPR    5EPS    5EQ1    5ERC    5ETB    5ETD    5EV9    5EVA    5EWC    5EWD    5EWH    5EWV    5EWW    5FFV    5FFW    5FFY    5FG4    5FG5    5G4R    5G4S   
SCOP (Structural Classification of Proteins)2D9E    2RS9    2X35    2X4W    2X4X    2X4Y    3L42    3MO8    4LC2    4QYD    4QYL    4UYE    5C6S    5C7N    5C85    5C87    5C89    5D7X    5DY7    5DYA    5DYC    5E3D    5E3G    5EM3    5EPR    5EPS    5EQ1    5ERC    5ETB    5ETD    5EV9    5EVA    5EWC    5EWD    5EWH    5EWV    5EWW    5FFV    5FFW    5FFY    5FG4    5FG5    5G4R    5G4S   
CATH (Classification of proteins structures)2D9E    2RS9    2X35    2X4W    2X4X    2X4Y    3L42    3MO8    4LC2    4QYD    4QYL    4UYE    5C6S    5C7N    5C85    5C87    5C89    5D7X    5DY7    5DYA    5DYC    5E3D    5E3G    5EM3    5EPR    5EPS    5EQ1    5ERC    5ETB    5ETD    5EV9    5EVA    5EWC    5EWD    5EWH    5EWV    5EWW    5FFV    5FFW    5FFY    5FG4    5FG5    5G4R    5G4S   
SuperfamilyP55201
Human Protein AtlasENSG00000156983
Peptide AtlasP55201
HPRD03875
IPIIPI00023856   IPI00456620   IPI00926602   IPI00925976   IPI00927952   IPI00927227   
Protein Interaction databases
DIP (DOE-UCLA)P55201
IntAct (EBI)P55201
FunCoupENSG00000156983
BioGRIDBRPF1
STRING (EMBL)BRPF1
ZODIACBRPF1
Ontologies - Pathways
QuickGOP55201
Ontology : AmiGODNA binding  protein binding  nucleus  nucleoplasm  cytoplasm  cytosol  plasma membrane  transcription, DNA-templated  zinc ion binding  histone H3 acetylation  histone H3-K23 acetylation  histone acetyltransferase activity (H3-K23 specific)  positive regulation of transcription, DNA-templated  MOZ/MORF histone acetyltransferase complex  regulation of signal transduction by p53 class mediator  
Ontology : EGO-EBIDNA binding  protein binding  nucleus  nucleoplasm  cytoplasm  cytosol  plasma membrane  transcription, DNA-templated  zinc ion binding  histone H3 acetylation  histone H3-K23 acetylation  histone acetyltransferase activity (H3-K23 specific)  positive regulation of transcription, DNA-templated  MOZ/MORF histone acetyltransferase complex  regulation of signal transduction by p53 class mediator  
NDEx NetworkBRPF1
Atlas of Cancer Signalling NetworkBRPF1
Wikipedia pathwaysBRPF1
Orthology - Evolution
OrthoDB7862
GeneTree (enSembl)ENSG00000156983
Phylogenetic Trees/Animal Genes : TreeFamBRPF1
HOVERGENP55201
HOGENOMP55201
Homologs : HomoloGeneBRPF1
Homology/Alignments : Family Browser (UCSC)BRPF1
Gene fusions - Rearrangements
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerBRPF1 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)BRPF1
dbVarBRPF1
ClinVarBRPF1
1000_GenomesBRPF1 
Exome Variant ServerBRPF1
ExAC (Exome Aggregation Consortium)BRPF1 (select the gene name)
Genetic variants : HAPMAP7862
Genomic Variants (DGV)BRPF1 [DGVbeta]
DECIPHERBRPF1 [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisBRPF1 
Mutations
ICGC Data PortalBRPF1 
TCGA Data PortalBRPF1 
Broad Tumor PortalBRPF1
OASIS PortalBRPF1 [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICBRPF1  [overview]  [genome browser]  [tissue]  [distribution]  
Mutations and Diseases : HGMDBRPF1
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD - Leiden Open Variation Database
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
BioMutasearch BRPF1
DgiDB (Drug Gene Interaction Database)BRPF1
DoCM (Curated mutations)BRPF1 (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)BRPF1 (select a term)
intoGenBRPF1
Cancer3DBRPF1(select the gene name)
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM602410    617333   
Orphanet
MedgenBRPF1
Genetic Testing Registry BRPF1
NextProtP55201 [Medical]
TSGene7862
GENETestsBRPF1
Target ValidationBRPF1
Huge Navigator BRPF1 [HugePedia]
snp3D : Map Gene to Disease7862
BioCentury BCIQBRPF1
ClinGenBRPF1
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD7862
Chemical/Pharm GKB GenePA25424
Clinical trialBRPF1
Miscellaneous
canSAR (ICR)BRPF1 (select the gene name)
Probes
Litterature
PubMed22 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineBRPF1
EVEXBRPF1
GoPubMedBRPF1
iHOPBRPF1
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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indexed on : Tue Aug 1 16:56:16 CEST 2017

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