Atlas of Genetics and Cytogenetics in Oncology and Haematology

Home   Genes   Leukemias   Solid Tumors   Cancer-Prone   Deep Insight   Case Reports   Journals  Portal   Teaching   
X Y 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22 NA

BST1 (bone marrow stromal cell antigen 1)

Identity

Alias_symbol (synonym)CD157
Other alias
HGNC (Hugo) BST1
LocusID (NCBI) 683
Atlas_Id 51656
Location 4p15.32  [Link to chromosome band 4p15]
Location_base_pair Starts at 15702950 and ends at 15732173 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2017)		Data from Atlas, Mitelman, Cosmic Fusion, Fusion Cancer, TCGA fusion databases with official HUGO symbols (see references in chromosomal bands)
BST1 (4p15.32) / SLTM (15q22.1)DGKG (3q27.2) / BST1 (4p15.32)

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 

Other Leukemias implicated (Data extracted from papers in the Atlas)

Leukemias TL_t0304q27p15ID2653

External links

Nomenclature
HGNC (Hugo)BST1   1118
Cards
Entrez_Gene (NCBI)BST1  683  bone marrow stromal cell antigen 1
AliasesCD157
GeneCards (Weizmann)BST1
Ensembl hg19 (Hinxton)ENSG00000109743 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000109743 [Gene_View]  ENSG00000109743 [Sequence]  chr4:15702950-15732173 [Contig_View]  BST1 [Vega]
ICGC DataPortalENSG00000109743
TCGA cBioPortalBST1
AceView (NCBI)BST1
Genatlas (Paris)BST1
WikiGenes683
SOURCE (Princeton)BST1
Genetics Home Reference (NIH)BST1
Genomic and cartography
GoldenPath hg38 (UCSC)BST1  -     chr4:15702950-15732173 +  4p15.32   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)BST1  -     4p15.32   [Description]    (hg19-Feb_2009)
GoldenPathBST1 - 4p15.32 [CytoView hg19]  BST1 - 4p15.32 [CytoView hg38]
ImmunoBaseENSG00000109743
Mapping of homologs : NCBIBST1 [Mapview hg19]  BST1 [Mapview hg38]
OMIM600387   
Gene and transcription
Genbank (Entrez)AB175627 AK312497 BC012095 BT019502 BU732655
RefSeq transcript (Entrez)NM_004334
RefSeq genomic (Entrez)
Consensus coding sequences : CCDS (NCBI)BST1
Cluster EST : UnigeneHs.720344 [ NCBI ]
CGAP (NCI)Hs.720344
Alternative Splicing GalleryENSG00000109743
Gene ExpressionBST1 [ NCBI-GEO ]   BST1 [ EBI - ARRAY_EXPRESS ]   BST1 [ SEEK ]   BST1 [ MEM ]
Gene Expression Viewer (FireBrowse)BST1 [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevestigatorExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)683
GTEX Portal (Tissue expression)BST1
Human Protein AtlasENSG00000109743-BST1 [pathology]   [cell]   [tissue]
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ10588   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtQ10588  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProQ10588
Splice isoforms : SwissVarQ10588
Catalytic activity : Enzyme3.2.2.5 [ Enzyme-Expasy ]   3.2.2.53.2.2.5 [ IntEnz-EBI ]   3.2.2.5 [ BRENDA ]   3.2.2.5 [ KEGG ]   
PhosPhoSitePlusQ10588
Domains : Interpro (EBI)ADP-ribosyl_cyclase   
Domain families : Pfam (Sanger)Rib_hydrolayse (PF02267)   
Domain families : Pfam (NCBI)pfam02267   
Conserved Domain (NCBI)BST1
DMDM Disease mutations683
Blocks (Seattle)BST1
PDB (RSDB)1ISF    1ISG    1ISH    1ISI    1ISJ    1ISM   
PDB Europe1ISF    1ISG    1ISH    1ISI    1ISJ    1ISM   
PDB (PDBSum)1ISF    1ISG    1ISH    1ISI    1ISJ    1ISM   
PDB (IMB)1ISF    1ISG    1ISH    1ISI    1ISJ    1ISM   
Structural Biology KnowledgeBase1ISF    1ISG    1ISH    1ISI    1ISJ    1ISM   
SCOP (Structural Classification of Proteins)1ISF    1ISG    1ISH    1ISI    1ISJ    1ISM   
CATH (Classification of proteins structures)1ISF    1ISG    1ISH    1ISI    1ISJ    1ISM   
SuperfamilyQ10588
Human Protein Atlas [tissue]ENSG00000109743-BST1 [tissue]
Peptide AtlasQ10588
HPRD02665
IPIIPI00026240   IPI00657860   IPI00967517   IPI00967860   IPI00968178   
Protein Interaction databases
DIP (DOE-UCLA)Q10588
IntAct (EBI)Q10588
FunCoupENSG00000109743
BioGRIDBST1
STRING (EMBL)BST1
ZODIACBST1
Ontologies - Pathways
QuickGOQ10588
Ontology : AmiGOuropod  regulation of cell-matrix adhesion  regulation of cellular extravasation  NAD+ nucleosidase activity  extracellular region  plasma membrane  plasma membrane  humoral immune response  signal transduction  positive regulation of cell proliferation  transferase activity  phosphorus-oxygen lyase activity  NAD metabolic process  extrinsic component of membrane  positive regulation of B cell proliferation  anchored component of membrane  regulation of actin cytoskeleton organization  specific granule membrane  neutrophil degranulation  NAD(P)+ nucleosidase activity  regulation of inflammatory response  regulation of peptidyl-tyrosine phosphorylation  regulation of calcium-mediated signaling  regulation of calcium-mediated signaling  NAD+ nucleotidase, cyclic ADP-ribose generating  ADP-ribosyl cyclase activity  cyclic ADP-ribose hydrolase  extracellular exosome  regulation of neutrophil chemotaxis  regulation of superoxide metabolic process  regulation of integrin-mediated signaling pathway  
Ontology : EGO-EBIuropod  regulation of cell-matrix adhesion  regulation of cellular extravasation  NAD+ nucleosidase activity  extracellular region  plasma membrane  plasma membrane  humoral immune response  signal transduction  positive regulation of cell proliferation  transferase activity  phosphorus-oxygen lyase activity  NAD metabolic process  extrinsic component of membrane  positive regulation of B cell proliferation  anchored component of membrane  regulation of actin cytoskeleton organization  specific granule membrane  neutrophil degranulation  NAD(P)+ nucleosidase activity  regulation of inflammatory response  regulation of peptidyl-tyrosine phosphorylation  regulation of calcium-mediated signaling  regulation of calcium-mediated signaling  NAD+ nucleotidase, cyclic ADP-ribose generating  ADP-ribosyl cyclase activity  cyclic ADP-ribose hydrolase  extracellular exosome  regulation of neutrophil chemotaxis  regulation of superoxide metabolic process  regulation of integrin-mediated signaling pathway  
Pathways : KEGGNicotinate and nicotinamide metabolism    Calcium signaling pathway    Salivary secretion    Pancreatic secretion    Epstein-Barr virus infection   
NDEx NetworkBST1
Atlas of Cancer Signalling NetworkBST1
Wikipedia pathwaysBST1
Orthology - Evolution
OrthoDB683
GeneTree (enSembl)ENSG00000109743
Phylogenetic Trees/Animal Genes : TreeFamBST1
HOGENOMQ10588
Homologs : HomoloGeneBST1
Homology/Alignments : Family Browser (UCSC)BST1
Gene fusions - Rearrangements
Fusion : MitelmanDGKG/BST1 [3q27.2/4p15.32]  [t(3;4)(q27;p15)]  
Fusion : QuiverBST1
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerBST1 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)BST1
dbVarBST1
ClinVarBST1
1000_GenomesBST1 
Exome Variant ServerBST1
ExAC (Exome Aggregation Consortium)ENSG00000109743
GNOMAD BrowserENSG00000109743
Varsome BrowserBST1
Genetic variants : HAPMAP683
Genomic Variants (DGV)BST1 [DGVbeta]
DECIPHERBST1 [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisBST1 
Mutations
ICGC Data PortalBST1 
TCGA Data PortalBST1 
Broad Tumor PortalBST1
OASIS PortalBST1 [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICBST1  [overview]  [genome browser]  [tissue]  [distribution]  
Somatic Mutations in Cancer : COSMIC3DBST1
Mutations and Diseases : HGMDBST1
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD - Leiden Open Variation Database
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
BioMutasearch BST1
DgiDB (Drug Gene Interaction Database)BST1
DoCM (Curated mutations)BST1 (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)BST1 (select a term)
intoGenBST1
Cancer3DBST1(select the gene name)
Impact of mutations[PolyPhen2] [Provean] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM600387   
Orphanet
DisGeNETBST1
MedgenBST1
Genetic Testing Registry BST1
NextProtQ10588 [Medical]
TSGene683
GENETestsBST1
Target ValidationBST1
Huge Navigator BST1 [HugePedia]
snp3D : Map Gene to Disease683
BioCentury BCIQBST1
ClinGenBST1
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD683
Chemical/Pharm GKB GenePA25435
Clinical trialBST1
Miscellaneous
canSAR (ICR)BST1 (select the gene name)
DataMed IndexBST1
Probes
Litterature
PubMed53 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineBST1
EVEXBST1
GoPubMedBST1
iHOPBST1
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

Search in all EBI   NCBI

© Atlas of Genetics and Cytogenetics in Oncology and Haematology
indexed on : Mon Aug 12 15:26:30 CEST 2019
Home   Genes   Leukemias   Solid Tumors   Cancer-Prone   Deep Insight   Case Reports   Journals  Portal   Teaching   

For comments and suggestions or contributions, please contact us

jlhuret@AtlasGeneticsOncology.org.