Atlas of Genetics and Cytogenetics in Oncology and Haematology


Home   Genes   Leukemias   Solid Tumors   Cancer-Prone   Deep Insight   Case Reports   Journals  Portal   Teaching   

X Y 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22 NA

BTAF1 (B-TFIID TATA-box binding protein associated factor 1)

Identity

Alias (NCBI)MOT1
TAF(II)170
TAF172
TAFII170
HGNC (Hugo) BTAF1
HGNC Alias symbTAFII170
TAF172
MOT1
TAF-172
TAF(II)170
HGNC Alias nameMot1 homolog (S. cerevisiae)
HGNC Previous nameBTAF1 RNA polymerase II, B-TFIID transcription factor-associated, 170 kD (Mot1 homolog, S. cerevisiae)
 BTAF1 RNA polymerase II, B-TFIID transcription factor-associated, 170kDa
LocusID (NCBI) 9044
Atlas_Id 846
Location 10q23.32  [Link to chromosome band 10q23]
Location_base_pair Starts at 91923770 and ends at 92031437 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2017)
Data from Atlas, Mitelman, Cosmic Fusion, Fusion Cancer, TCGA fusion databases with official HUGO symbols (see references in chromosomal bands)
CALM2 (2p21) / BTAF1 (10q23.32)CFAP45 (1q23.2) / BTAF1 (10q23.32)

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 



External links

 

Nomenclature
HGNC (Hugo)BTAF1   17307
Cards
Entrez_Gene (NCBI)BTAF1    B-TFIID TATA-box binding protein associated factor 1
AliasesMOT1; TAF(II)170; TAF172; TAFII170
GeneCards (Weizmann)BTAF1
Ensembl hg19 (Hinxton)ENSG00000095564 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000095564 [Gene_View]  ENSG00000095564 [Sequence]  chr10:91923770-92031437 [Contig_View]  BTAF1 [Vega]
ICGC DataPortalENSG00000095564
TCGA cBioPortalBTAF1
AceView (NCBI)BTAF1
Genatlas (Paris)BTAF1
SOURCE (Princeton)BTAF1
Genetics Home Reference (NIH)BTAF1
Genomic and cartography
GoldenPath hg38 (UCSC)BTAF1  -     chr10:91923770-92031437 +  10q23.32   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)BTAF1  -     10q23.32   [Description]    (hg19-Feb_2009)
GoldenPathBTAF1 - 10q23.32 [CytoView hg19]  BTAF1 - 10q23.32 [CytoView hg38]
ImmunoBaseENSG00000095564
Genome Data Viewer NCBIBTAF1 [Mapview hg19]  
OMIM605191   
Gene and transcription
Genbank (Entrez)AB208843 AF038362 AJ001017 AK303554 AK308399
RefSeq transcript (Entrez)NM_003972
Consensus coding sequences : CCDS (NCBI)BTAF1
Gene ExpressionBTAF1 [ NCBI-GEO ]   BTAF1 [ EBI - ARRAY_EXPRESS ]   BTAF1 [ SEEK ]   BTAF1 [ MEM ]
Gene Expression Viewer (FireBrowse)BTAF1 [ Firebrowse - Broad ]
GenevisibleExpression of BTAF1 in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)9044
GTEX Portal (Tissue expression)BTAF1
Human Protein AtlasENSG00000095564-BTAF1 [pathology]   [cell]   [tissue]
Protein : pattern, domain, 3D structure
UniProt/SwissProtO14981   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtO14981  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProO14981
Catalytic activity : Enzyme3.6.4.- [ Enzyme-Expasy ]   3.6.4.-3.6.4.- [ IntEnz-EBI ]   3.6.4.- [ BRENDA ]   3.6.4.- [ KEGG ]   [ MEROPS ]
PhosPhoSitePlusO14981
Domaine pattern : Prosite (Expaxy)HELICASE_ATP_BIND_1 (PS51192)    HELICASE_CTER (PS51194)   
Domains : Interpro (EBI)ARM-like    ARM-type_fold    DUF3535    Helicase_ATP-bd    Helicase_C    Mot1_ATP-bd    P-loop_NTPase    SNF2-like_sf    SNF2_N   
Domain families : Pfam (Sanger)DUF3535 (PF12054)    Helicase_C (PF00271)    SNF2_N (PF00176)   
Domain families : Pfam (NCBI)pfam12054    pfam00271    pfam00176   
Domain families : Smart (EMBL)DEXDc (SM00487)  HELICc (SM00490)  
Conserved Domain (NCBI)BTAF1
SuperfamilyO14981
AlphaFold pdb e-kbO14981   
Human Protein Atlas [tissue]ENSG00000095564-BTAF1 [tissue]
HPRD05546
Protein Interaction databases
DIP (DOE-UCLA)O14981
IntAct (EBI)O14981
BioGRIDBTAF1
STRING (EMBL)BTAF1
ZODIACBTAF1
Ontologies - Pathways
QuickGOO14981
Ontology : AmiGODNA binding  transcription coregulator activity  helicase activity  ATP binding  nucleoplasm  ATPase, acting on DNA  hydrolase activity  negative regulation of chromatin binding  intracellular membrane-bounded organelle  negative regulation of transcription, DNA-templated  nucleosome-dependent ATPase activity  
Ontology : EGO-EBIDNA binding  transcription coregulator activity  helicase activity  ATP binding  nucleoplasm  ATPase, acting on DNA  hydrolase activity  negative regulation of chromatin binding  intracellular membrane-bounded organelle  negative regulation of transcription, DNA-templated  nucleosome-dependent ATPase activity  
NDEx NetworkBTAF1
Atlas of Cancer Signalling NetworkBTAF1
Wikipedia pathwaysBTAF1
Orthology - Evolution
OrthoDB9044
GeneTree (enSembl)ENSG00000095564
Phylogenetic Trees/Animal Genes : TreeFamBTAF1
Homologs : HomoloGeneBTAF1
Homology/Alignments : Family Browser (UCSC)BTAF1
Gene fusions - Rearrangements
Fusion : QuiverBTAF1
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerBTAF1 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)BTAF1
dbVarBTAF1
ClinVarBTAF1
MonarchBTAF1
1000_GenomesBTAF1 
Exome Variant ServerBTAF1
GNOMAD BrowserENSG00000095564
Varsome BrowserBTAF1
ACMGBTAF1 variants
VarityO14981
Genomic Variants (DGV)BTAF1 [DGVbeta]
DECIPHERBTAF1 [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisBTAF1 
Mutations
ICGC Data PortalBTAF1 
TCGA Data PortalBTAF1 
Broad Tumor PortalBTAF1
OASIS PortalBTAF1 [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICBTAF1  [overview]  [genome browser]  [tissue]  [distribution]  
Somatic Mutations in Cancer : COSMIC3DBTAF1
Mutations and Diseases : HGMDBTAF1
LOVD (Leiden Open Variation Database)[gene] [transcripts] [variants]
BioMutaBTAF1
DgiDB (Drug Gene Interaction Database)BTAF1
DoCM (Curated mutations)BTAF1
CIViC (Clinical Interpretations of Variants in Cancer)BTAF1
Cancer3DBTAF1
Impact of mutations[PolyPhen2] [Provean] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM605191   
Orphanet
DisGeNETBTAF1
MedgenBTAF1
Genetic Testing Registry BTAF1
NextProtO14981 [Medical]
GENETestsBTAF1
Target ValidationBTAF1
Huge Navigator BTAF1 [HugePedia]
ClinGenBTAF1
Clinical trials, drugs, therapy
MyCancerGenomeBTAF1
Protein Interactions : CTDBTAF1
Pharm GKB GenePA25437
PharosO14981
Clinical trialBTAF1
Miscellaneous
canSAR (ICR)BTAF1
HarmonizomeBTAF1
DataMed IndexBTAF1
Probes
Litterature
PubMed61 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
EVEXBTAF1
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

Search in all EBI   NCBI

© Atlas of Genetics and Cytogenetics in Oncology and Haematology
indexed on : Mon Oct 4 15:01:31 CEST 2021

Home   Genes   Leukemias   Solid Tumors   Cancer-Prone   Deep Insight   Case Reports   Journals  Portal   Teaching   

For comments and suggestions or contributions, please contact us

jlhuret@AtlasGeneticsOncology.org.