Atlas of Genetics and Cytogenetics in Oncology and Haematology


Home   Genes   Leukemias   Solid Tumors   Cancer-Prone   Deep Insight   Case Reports   Journals  Portal   Teaching   

X Y 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22 NA

BTN3A1 (butyrophilin subfamily 3 member A1)

Identity

Alias_namesbutyrophilin
Alias_symbol (synonym)BT3.1
BTF5
CD277
BTN3.1
Other alias
HGNC (Hugo) BTN3A1
LocusID (NCBI) 11119
Atlas_Id 52247
Location 6p22.2  [Link to chromosome band 6p22]
Location_base_pair Starts at 26402237 and ends at 26415216 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2017)
Data from Atlas, Mitelman, Cosmic Fusion, Fusion Cancer, TCGA fusion databases with official HUGO symbols (see references in chromosomal bands)
BTN3A1 (6p22.2) / BTN3A3 (6p22.2)BTN3A1 (6p22.2) / IQSEC1 (3p25.2)BTN3A2 (6p22.2) / BTN3A1 (6p22.2)

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


External links

Nomenclature
HGNC (Hugo)BTN3A1   1138
Cards
Entrez_Gene (NCBI)BTN3A1  11119  butyrophilin subfamily 3 member A1
AliasesBT3.1; BTF5; BTN3.1; CD277
GeneCards (Weizmann)BTN3A1
Ensembl hg19 (Hinxton)ENSG00000026950 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000026950 [Gene_View]  ENSG00000026950 [Sequence]  chr6:26402237-26415216 [Contig_View]  BTN3A1 [Vega]
ICGC DataPortalENSG00000026950
TCGA cBioPortalBTN3A1
AceView (NCBI)BTN3A1
Genatlas (Paris)BTN3A1
WikiGenes11119
SOURCE (Princeton)BTN3A1
Genetics Home Reference (NIH)BTN3A1
Genomic and cartography
GoldenPath hg38 (UCSC)BTN3A1  -     chr6:26402237-26415216 +  6p22.2   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)BTN3A1  -     6p22.2   [Description]    (hg19-Feb_2009)
EnsemblBTN3A1 - 6p22.2 [CytoView hg19]  BTN3A1 - 6p22.2 [CytoView hg38]
Mapping of homologs : NCBIBTN3A1 [Mapview hg19]  BTN3A1 [Mapview hg38]
OMIM613593   
Gene and transcription
Genbank (Entrez)AA977088 AK223474 AK290193 AK291162 AK295720
RefSeq transcript (Entrez)NM_001145008 NM_001145009 NM_007048 NM_194441
RefSeq genomic (Entrez)
Consensus coding sequences : CCDS (NCBI)BTN3A1
Cluster EST : UnigeneHs.191510 [ NCBI ]
CGAP (NCI)Hs.191510
Alternative Splicing GalleryENSG00000026950
Gene ExpressionBTN3A1 [ NCBI-GEO ]   BTN3A1 [ EBI - ARRAY_EXPRESS ]   BTN3A1 [ SEEK ]   BTN3A1 [ MEM ]
Gene Expression Viewer (FireBrowse)BTN3A1 [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevestigatorExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)11119
GTEX Portal (Tissue expression)BTN3A1
Human Protein AtlasENSG00000026950-BTN3A1 [pathology]   [cell]   [tissue]
Protein : pattern, domain, 3D structure
UniProt/SwissProtO00481   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtO00481  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProO00481
Splice isoforms : SwissVarO00481
PhosPhoSitePlusO00481
Domaine pattern : Prosite (Expaxy)B302_SPRY (PS50188)    IG_LIKE (PS50835)   
Domains : Interpro (EBI)B30.2/SPRY    Butyrophylin_SPRY    ConA-like_dom_sf    Ig-like_dom    Ig-like_dom_sf    Ig-like_fold    Ig_sub    Ig_V-set    PRY    SPRY_dom    SPRY_PRY_BTN3   
Domain families : Pfam (Sanger)PRY (PF13765)    SPRY (PF00622)    V-set (PF07686)   
Domain families : Pfam (NCBI)pfam13765    pfam00622    pfam07686   
Domain families : Smart (EMBL)IG (SM00409)  IGv (SM00406)  PRY (SM00589)  SPRY (SM00449)  
Conserved Domain (NCBI)BTN3A1
DMDM Disease mutations11119
Blocks (Seattle)BTN3A1
PDB (SRS)4F80    4F9L    4F9P    4JKW    4K55    4N7I    4N7U    4V1P    5HM7    5LYG    5LYK   
PDB (PDBSum)4F80    4F9L    4F9P    4JKW    4K55    4N7I    4N7U    4V1P    5HM7    5LYG    5LYK   
PDB (IMB)4F80    4F9L    4F9P    4JKW    4K55    4N7I    4N7U    4V1P    5HM7    5LYG    5LYK   
PDB (RSDB)4F80    4F9L    4F9P    4JKW    4K55    4N7I    4N7U    4V1P    5HM7    5LYG    5LYK   
Structural Biology KnowledgeBase4F80    4F9L    4F9P    4JKW    4K55    4N7I    4N7U    4V1P    5HM7    5LYG    5LYK   
SCOP (Structural Classification of Proteins)4F80    4F9L    4F9P    4JKW    4K55    4N7I    4N7U    4V1P    5HM7    5LYG    5LYK   
CATH (Classification of proteins structures)4F80    4F9L    4F9P    4JKW    4K55    4N7I    4N7U    4V1P    5HM7    5LYG    5LYK   
SuperfamilyO00481
Human Protein Atlas [tissue]ENSG00000026950-BTN3A1 [tissue]
Peptide AtlasO00481
HPRD10693
IPIIPI00383474   IPI00375709   IPI00966610   IPI00909099   IPI00921230   IPI00877628   IPI01012988   
Protein Interaction databases
DIP (DOE-UCLA)O00481
IntAct (EBI)O00481
FunCoupENSG00000026950
BioGRIDBTN3A1
STRING (EMBL)BTN3A1
ZODIACBTN3A1
Ontologies - Pathways
QuickGOO00481
Ontology : AmiGOadaptive immune response  signaling receptor binding  protein binding  plasma membrane  plasma membrane  external side of plasma membrane  integral component of membrane  cytokine secretion  regulation of immune response  activated T cell proliferation  T cell receptor signaling pathway  T cell receptor signaling pathway  interferon-gamma secretion  
Ontology : EGO-EBIadaptive immune response  signaling receptor binding  protein binding  plasma membrane  plasma membrane  external side of plasma membrane  integral component of membrane  cytokine secretion  regulation of immune response  activated T cell proliferation  T cell receptor signaling pathway  T cell receptor signaling pathway  interferon-gamma secretion  
NDEx NetworkBTN3A1
Atlas of Cancer Signalling NetworkBTN3A1
Wikipedia pathwaysBTN3A1
Orthology - Evolution
OrthoDB11119
GeneTree (enSembl)ENSG00000026950
Phylogenetic Trees/Animal Genes : TreeFamBTN3A1
HOVERGENO00481
HOGENOMO00481
Homologs : HomoloGeneBTN3A1
Homology/Alignments : Family Browser (UCSC)BTN3A1
Gene fusions - Rearrangements
Fusion Cancer (Beijing)BTN3A1 [6p22.2]  -  BTN3A3 [6p22.2]  [FUSC000949]
Fusion Cancer (Beijing)BTN3A2 [6p22.2]  -  BTN3A1 [6p22.2]  [FUSC000773]
Fusion : QuiverBTN3A1
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerBTN3A1 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)BTN3A1
dbVarBTN3A1
ClinVarBTN3A1
1000_GenomesBTN3A1 
Exome Variant ServerBTN3A1
ExAC (Exome Aggregation Consortium)ENSG00000026950
GNOMAD BrowserENSG00000026950
Varsome BrowserBTN3A1
Genetic variants : HAPMAP11119
Genomic Variants (DGV)BTN3A1 [DGVbeta]
DECIPHERBTN3A1 [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisBTN3A1 
Mutations
ICGC Data PortalBTN3A1 
TCGA Data PortalBTN3A1 
Broad Tumor PortalBTN3A1
OASIS PortalBTN3A1 [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICBTN3A1  [overview]  [genome browser]  [tissue]  [distribution]  
Mutations and Diseases : HGMDBTN3A1
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD - Leiden Open Variation Database
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
BioMutasearch BTN3A1
DgiDB (Drug Gene Interaction Database)BTN3A1
DoCM (Curated mutations)BTN3A1 (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)BTN3A1 (select a term)
intoGenBTN3A1
Cancer3DBTN3A1(select the gene name)
Impact of mutations[PolyPhen2] [Provean] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM613593   
Orphanet
DisGeNETBTN3A1
MedgenBTN3A1
Genetic Testing Registry BTN3A1
NextProtO00481 [Medical]
TSGene11119
GENETestsBTN3A1
Target ValidationBTN3A1
Huge Navigator BTN3A1 [HugePedia]
snp3D : Map Gene to Disease11119
BioCentury BCIQBTN3A1
ClinGenBTN3A1
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD11119
Chemical/Pharm GKB GenePA25459
Clinical trialBTN3A1
Miscellaneous
canSAR (ICR)BTN3A1 (select the gene name)
Probes
Litterature
PubMed28 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineBTN3A1
EVEXBTN3A1
GoPubMedBTN3A1
iHOPBTN3A1
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

Search in all EBI   NCBI

© Atlas of Genetics and Cytogenetics in Oncology and Haematology
indexed on : Tue Nov 6 10:54:40 CET 2018

Home   Genes   Leukemias   Solid Tumors   Cancer-Prone   Deep Insight   Case Reports   Journals  Portal   Teaching   

For comments and suggestions or contributions, please contact us

jlhuret@AtlasGeneticsOncology.org.