Identity
HGNC
LOCATION
6p22.2
LOCUSID
ALIAS
BT3.1,BTF5,BTN3.1,CD277
FUSION GENES
Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, contribute in submission tool
Other Information
Locus ID:
NCBI: 11119
MIM: 613593
HGNC: 1138
Ensembl: ENSG00000026950
Variants:
dbSNP: 11119
ClinVar: 11119
TCGA: ENSG00000026950
COSMIC: BTN3A1
RNA/Proteins
Expression (GTEx)
Pathways
| Pathway | Source | External ID |
|---|---|---|
| Immune System | REACTOME | R-HSA-168256 |
| Adaptive Immune System | REACTOME | R-HSA-1280218 |
| Butyrophilin (BTN) family interactions | REACTOME | R-HSA-8851680 |
Protein levels (Protein atlas)
References
| Pubmed ID | Year | Title | Citations |
|---|---|---|---|
| 37688767 | 2024 | Synergistic effects of BTN3A1, SHP2, CD274, and STAT3 gene polymorphisms on the risk of systemic lupus erythematosus: a multifactorial dimensional reduction analysis. | 1 |
| 38450995 | 2024 | Association of BTN3A1 gene polymorphisms with systemic lupus erythematosus in a Chinese Han population. | 1 |
| 37688767 | 2024 | Synergistic effects of BTN3A1, SHP2, CD274, and STAT3 gene polymorphisms on the risk of systemic lupus erythematosus: a multifactorial dimensional reduction analysis. | 1 |
| 38450995 | 2024 | Association of BTN3A1 gene polymorphisms with systemic lupus erythematosus in a Chinese Han population. | 1 |
| 37171180 | 2023 | Mutations to the BTN2A1 Linker Region Impact Its Homodimerization and Its Cytoplasmic Interaction with Phospho-Antigen-Bound BTN3A1. | 2 |
| 37674084 | 2023 | Phosphoantigens glue butyrophilin 3A1 and 2A1 to activate Vγ9Vδ2 T cells. | 12 |
| 37171180 | 2023 | Mutations to the BTN2A1 Linker Region Impact Its Homodimerization and Its Cytoplasmic Interaction with Phospho-Antigen-Bound BTN3A1. | 2 |
| 37674084 | 2023 | Phosphoantigens glue butyrophilin 3A1 and 2A1 to activate Vγ9Vδ2 T cells. | 12 |
| 34545848 | 2022 | Elevated Expressions of BTN3A1 and RhoB in Psoriasis Vulgaris Lesions by an Immunohistochemical Study. | 1 |
| 34952469 | 2022 | Expression level of BTN3A1 on the surface of CD14(+) monocytes is a potential predictor of γδ T cell expansion efficiency. | 2 |
| 35081362 | 2022 | Ligand-induced interactions between butyrophilin 2A1 and 3A1 internal domains in the HMBPP receptor complex. | 16 |
| 36288286 | 2022 | Up-regulation of BTN3A1 on CD14(+) cells promotes Vγ9Vδ2 T cell activation in psoriasis. | 5 |
| 36362212 | 2022 | BTN3A: A Promising Immune Checkpoint for Cancer Prognosis and Treatment. | 5 |
| 36418890 | 2022 | BTN3A1 promotes tumor progression and radiation resistance in esophageal squamous cell carcinoma by regulating ULK1-mediated autophagy. | 6 |
| 34545848 | 2022 | Elevated Expressions of BTN3A1 and RhoB in Psoriasis Vulgaris Lesions by an Immunohistochemical Study. | 1 |
Citation
Dessen P
BTN3A1 (butyrophilin subfamily 3 member A1)
Atlas Genet Cytogenet Oncol Haematol. 2011-06-01
Online version: http://atlasgeneticsoncology.org/gene/52247/btn3a1
