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BZW2 (basic leucine zipper and W2 domains 2)

Identity

Other aliasHSPC028
MST017
MSTP017
HGNC (Hugo) BZW2
LocusID (NCBI) 28969
Atlas_Id 57448
Location 7p21.1  [Link to chromosome band 7p21]
Location_base_pair Starts at 16646134 and ends at 16706523 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2017)
Data from Atlas, Mitelman, Cosmic Fusion, Fusion Cancer, TCGA fusion databases with official HUGO symbols (see references in chromosomal bands)
BZW2 (7p21.1) / BZW2 (7p21.1)BZW2 (7p21.1) / GUSB (7q11.21)BZW2 (7p21.1) / KIF13A (6p22.3)
BZW2 (7p21.1) / PPP1R12B (1q32.1)ERG (21q22.2) / BZW2 (7p21.1)

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


Other Leukemias implicated (Data extracted from papers in the Atlas) [ 3 ]
  t(7;7)(p15;p21) HOXA11/BZW2
t(7;7)(p21;q11) BZW2/GUSB
t(X;7)(q25;p21) STAG2/BZW2


Other Solid tumors implicated (Data extracted from papers in the Atlas) [ 1 ]
  t(7;17)(p21;p13) RPH3AL/BZW2


External links

Nomenclature
HGNC (Hugo)BZW2   18808
Cards
Entrez_Gene (NCBI)BZW2  28969  basic leucine zipper and W2 domains 2
AliasesHSPC028; MST017; MSTP017
GeneCards (Weizmann)BZW2
Ensembl hg19 (Hinxton) [Gene_View]
Ensembl hg38 (Hinxton) [Gene_View]   [Sequence]  chr7:16646134-16706523 [Contig_View]  BZW2 [Vega]
TCGA cBioPortalBZW2
AceView (NCBI)BZW2
Genatlas (Paris)BZW2
WikiGenes28969
SOURCE (Princeton)BZW2
Genetics Home Reference (NIH)BZW2
Genomic and cartography
GoldenPath hg38 (UCSC)BZW2  -     chr7:16646134-16706523 +  7p21.1   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)BZW2  -     7p21.1   [Description]    (hg19-Feb_2009)
EnsemblBZW2 - 7p21.1 [CytoView hg19]  BZW2 - 7p21.1 [CytoView hg38]
Mapping of homologs : NCBIBZW2 [Mapview hg19]  BZW2 [Mapview hg38]
Gene and transcription
Genbank (Entrez)AA429958 AF083246 AF110323 AK001218 AK001260
RefSeq transcript (Entrez)NM_001159767 NM_001362717 NM_001362718 NM_001362719 NM_014038
RefSeq genomic (Entrez)
Consensus coding sequences : CCDS (NCBI)BZW2
Cluster EST : UnigeneHs.487635 [ NCBI ]
CGAP (NCI)Hs.487635
Gene ExpressionBZW2 [ NCBI-GEO ]   BZW2 [ EBI - ARRAY_EXPRESS ]   BZW2 [ SEEK ]   BZW2 [ MEM ]
Gene Expression Viewer (FireBrowse)BZW2 [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevestigatorExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)28969
GTEX Portal (Tissue expression)BZW2
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ9Y6E2   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtQ9Y6E2  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProQ9Y6E2
Splice isoforms : SwissVarQ9Y6E2
PhosPhoSitePlusQ9Y6E2
Domaine pattern : Prosite (Expaxy)W2 (PS51363)   
Domains : Interpro (EBI)ARM-type_fold    MIF4-like_sf    W2_domain   
Domain families : Pfam (Sanger)W2 (PF02020)   
Domain families : Pfam (NCBI)pfam02020   
Domain families : Smart (EMBL)eIF5C (SM00515)  
Conserved Domain (NCBI)BZW2
DMDM Disease mutations28969
Blocks (Seattle)BZW2
SuperfamilyQ9Y6E2
Peptide AtlasQ9Y6E2
IPIIPI00022305   IPI00892775   IPI00807524   IPI00064431   IPI00894416   IPI00892637   IPI00892766   IPI00892893   IPI00893030   IPI00893174   
Protein Interaction databases
DIP (DOE-UCLA)Q9Y6E2
IntAct (EBI)Q9Y6E2
BioGRIDBZW2
STRING (EMBL)BZW2
ZODIACBZW2
Ontologies - Pathways
QuickGOQ9Y6E2
Ontology : AmiGOprotein binding  cytoplasm  cytoplasm  nervous system development  membrane  cell differentiation  cadherin binding  
Ontology : EGO-EBIprotein binding  cytoplasm  cytoplasm  nervous system development  membrane  cell differentiation  cadherin binding  
NDEx NetworkBZW2
Atlas of Cancer Signalling NetworkBZW2
Wikipedia pathwaysBZW2
Orthology - Evolution
OrthoDB28969
Phylogenetic Trees/Animal Genes : TreeFamBZW2
HOVERGENQ9Y6E2
HOGENOMQ9Y6E2
Homologs : HomoloGeneBZW2
Homology/Alignments : Family Browser (UCSC)BZW2
Gene fusions - Rearrangements
Fusion : QuiverBZW2
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerBZW2 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)BZW2
dbVarBZW2
ClinVarBZW2
1000_GenomesBZW2 
Exome Variant ServerBZW2
Varsome BrowserBZW2
Genetic variants : HAPMAP28969
Genomic Variants (DGV)BZW2 [DGVbeta]
DECIPHERBZW2 [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisBZW2 
Mutations
ICGC Data PortalBZW2 
TCGA Data PortalBZW2 
Broad Tumor PortalBZW2
OASIS PortalBZW2 [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICBZW2  [overview]  [genome browser]  [tissue]  [distribution]  
Mutations and Diseases : HGMDBZW2
BioMutasearch BZW2
DgiDB (Drug Gene Interaction Database)BZW2
DoCM (Curated mutations)BZW2 (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)BZW2 (select a term)
intoGenBZW2
Cancer3DBZW2(select the gene name)
Impact of mutations[PolyPhen2] [Provean] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM
Orphanet
DisGeNETBZW2
MedgenBZW2
Genetic Testing Registry BZW2
NextProtQ9Y6E2 [Medical]
TSGene28969
GENETestsBZW2
Target ValidationBZW2
Huge Navigator BZW2 [HugePedia]
snp3D : Map Gene to Disease28969
BioCentury BCIQBZW2
ClinGenBZW2
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD28969
Chemical/Pharm GKB GenePA38690
Clinical trialBZW2
Miscellaneous
canSAR (ICR)BZW2 (select the gene name)
Probes
Litterature
PubMed40 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineBZW2
EVEXBZW2
GoPubMedBZW2
iHOPBZW2
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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indexed on : Mon Aug 27 11:12:07 CEST 2018

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