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Taking over the Atlas
Dear Colleagues,
The Atlas, once more, is in great danger, and I will have to proceed to a collective economic lay-off of all the team involved in the Atlas before the begining of April 2015 (a foundation having suddenly withdrawn its commitment to support the Atlas). I ask you herein if any Scientific Society (a Society of Cytogenetics, of Clinical Genetics, of Hematology, or a Cancer Society, or any other...), any University and/or Hospital, any Charity, or any database would be interested in taking over the Atlas, in whole or in part. If taking charge of the whole lot is too big, a consortium of various actors could be the solution (I am myself trying to find partners). Could you please spread the information, contact the relevant authorities, and find partners.
Survival of the Atlas will be critically dependant upon your ability to find solutions (and urgently!).
Kind regards.
Jean-Loup Huret
Donations are also welcome

Donate (in Euros)

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C10orf2 (chromosome 10 open reading frame 2)

Identity

Other namesATXN8
IOSCA
MTDPS7
PEO
PEO1
PEOA3
SANDO
SCA8
TWINL
HGNC (Hugo) C10orf2
LocusID (NCBI) 56652
Location 10q24.31
Location_base_pair Starts at 102747293 and ends at 102754158 bp from pter ( according to hg19-Feb_2009)
Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

External links

Nomenclature
HGNC (Hugo)C10orf2   1160
Cards
Entrez_Gene (NCBI)C10orf2  56652  chromosome 10 open reading frame 2
GeneCards (Weizmann)C10orf2
Ensembl hg19 (Hinxton)ENSG00000107815 [Gene_View]  chr10:102747293-102754158 [Contig_View]  C10orf2 [Vega]
Ensembl hg38 (Hinxton)ENSG00000107815 [Gene_View]  chr10:102747293-102754158 [Contig_View]  C10orf2 [Vega]
ICGC DataPortalENSG00000107815
cBioPortalC10orf2
AceView (NCBI)C10orf2
Genatlas (Paris)C10orf2
WikiGenes56652
SOURCE (Princeton)C10orf2
Genomic and cartography
GoldenPath hg19 (UCSC)C10orf2  -     chr10:102747293-102754158 +  10q24.31   [Description]    (hg19-Feb_2009)
GoldenPath hg38 (UCSC)C10orf2  -     10q24.31   [Description]    (hg38-Dec_2013)
EnsemblC10orf2 - 10q24.31 [CytoView hg19]  C10orf2 - 10q24.31 [CytoView hg38]
Mapping of homologs : NCBIC10orf2 [Mapview hg19]  C10orf2 [Mapview hg38]
OMIM271245   606075   607459   609286   
Gene and transcription
Genbank (Entrez)AF292004 AF292005 AK022959 AK025485 AK297068
RefSeq transcript (Entrez)NM_001163812 NM_001163813 NM_001163814 NM_021830
RefSeq genomic (Entrez)AC_000142 NC_000010 NC_018921 NG_012624 NT_030059 NW_001838006 NW_004929376
Consensus coding sequences : CCDS (NCBI)C10orf2
Cluster EST : UnigeneHs.22678 [ NCBI ]
CGAP (NCI)Hs.22678
Alternative Splicing : Fast-db (Paris)GSHG0003625
Alternative Splicing GalleryENSG00000107815
Gene ExpressionC10orf2 [ NCBI-GEO ]     C10orf2 [ SEEK ]   C10orf2 [ MEM ]
SOURCE (Princeton)Expression in : [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ96RR1 (Uniprot)
NextProtQ96RR1  [Medical]
With graphics : InterProQ96RR1
Splice isoforms : SwissVarQ96RR1 (Swissvar)
Catalytic activity : Enzyme3.6.4.12 [ Enzyme-Expasy ]   3.6.4.123.6.4.12 [ IntEnz-EBI ]   3.6.4.12 [ BRENDA ]   3.6.4.12 [ KEGG ]   
Domaine pattern : Prosite (Expaxy)SF4_HELICASE (PS51199)   
Domains : Interpro (EBI)DNA_helicase_DnaB-like_C    P-loop_NTPase    Twinkle   
Related proteins : CluSTrQ96RR1
Domain families : Pfam (Sanger)
Domain families : Pfam (NCBI)
DMDM Disease mutations56652
Blocks (Seattle)Q96RR1
Human Protein AtlasENSG00000107815
Peptide AtlasQ96RR1
HPRD05830
IPIIPI00102660   IPI00640641   IPI00654621   IPI00943680   IPI00943723   
Protein Interaction databases
DIP (DOE-UCLA)Q96RR1
IntAct (EBI)Q96RR1
FunCoupENSG00000107815
BioGRIDC10orf2
IntegromeDBC10orf2
STRING (EMBL)C10orf2
Ontologies - Pathways
QuickGOQ96RR1
Ontology : AmiGOprotease binding  single-stranded DNA binding  ATP binding  mitochondrial DNA replication  mitochondrial DNA replication  DNA unwinding involved in DNA replication  transcription from mitochondrial promoter  cell death  protein hexamerization  mitochondrial nucleoid  5'-3' DNA helicase activity  protein homooligomerization  
Ontology : EGO-EBIprotease binding  single-stranded DNA binding  ATP binding  mitochondrial DNA replication  mitochondrial DNA replication  DNA unwinding involved in DNA replication  transcription from mitochondrial promoter  cell death  protein hexamerization  mitochondrial nucleoid  5'-3' DNA helicase activity  protein homooligomerization  
Protein Interaction DatabaseC10orf2
DoCM (Curated mutations)C10orf2
Wikipedia pathwaysC10orf2
Gene fusion - rearrangements
Polymorphisms : SNP, variants
NCBI Variation ViewerC10orf2 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)C10orf2
dbVarC10orf2
ClinVarC10orf2
1000_GenomesC10orf2 
Exome Variant ServerC10orf2
SNP (GeneSNP Utah)C10orf2
SNP : HGBaseC10orf2
Genetic variants : HAPMAPC10orf2
Genomic Variants (DGV)C10orf2 [DGVbeta]
Mutations
ICGC Data PortalENSG00000107815 
Somatic Mutations in Cancer : COSMICC10orf2 
CONAN: Copy Number AnalysisC10orf2 
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD - Leiden Open Variation Database
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
LOVD (Leiden Open Variation Database)MSeqDR-LSDB Mitochondrial Disease Locus Specific Database
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] 
Diseases
DECIPHER (Syndromes)10:102747293-102754158
Mutations and Diseases : HGMDC10orf2
OMIM271245    606075    607459    609286   
MedgenC10orf2
NextProtQ96RR1 [Medical]
GENETestsC10orf2
Disease Genetic AssociationC10orf2
Huge Navigator C10orf2 [HugePedia]  C10orf2 [HugeCancerGEM]
snp3D : Map Gene to Disease56652
DGIdb (Drug Gene Interaction db)C10orf2
General knowledge
Homologs : HomoloGeneC10orf2
Homology/Alignments : Family Browser (UCSC)C10orf2
Phylogenetic Trees/Animal Genes : TreeFamC10orf2
Chemical/Protein Interactions : CTD56652
Chemical/Pharm GKB GenePA162377675
Clinical trialC10orf2
Cancer Resource (Charite)ENSG00000107815
Other databases
Probes
Litterature
PubMed69 Pubmed reference(s) in Entrez
CoreMineC10orf2
GoPubMedC10orf2
iHOPC10orf2
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

Search in all EBI   NCBI

Contributor(s)

Written09-2002Dessen P, Le Minor S
Updated12-2014Dessen P

© Atlas of Genetics and Cytogenetics in Oncology and Haematology
indexed on : Sat Feb 14 14:51:56 CET 2015

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For comments and suggestions or contributions, please contact us

jlhuret@AtlasGeneticsOncology.org.