Atlas of Genetics and Cytogenetics in Oncology and Haematology


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C10orf2 (chromosome 10 open reading frame 2)

Identity

HGNC (Hugo) C10orf2
LocusID (NCBI) 56652
Atlas_Id 52779
Location 10q24.31  [Link to chromosome band 10q24]
Location_base_pair Starts at 102747293 and ends at 102754158 bp from pter ( according to hg19-Feb_2009)
Fusion genes
(updated 2016)
LOC100507412 (-) / C10orf2 (10q24.31)STOML2 (9p13.3) / C10orf2 (10q24.31)

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


External links

Nomenclature
HGNC (Hugo)C10orf2   1160
Cards
Entrez_Gene (NCBI)C10orf2  56652  chromosome 10 open reading frame 2
AliasesATXN8; IOSCA; MTDPS7; PEO; 
PEO1; PEOA3; PRLTS5; SANDO; SCA8; TWINL
GeneCards (Weizmann)C10orf2
Ensembl hg19 (Hinxton)ENSG00000107815 [Gene_View]  chr10:102747293-102754158 [Contig_View]  C10orf2 [Vega]
Ensembl hg38 (Hinxton)ENSG00000107815 [Gene_View]  chr10:102747293-102754158 [Contig_View]  C10orf2 [Vega]
ICGC DataPortalENSG00000107815
TCGA cBioPortalC10orf2
AceView (NCBI)C10orf2
Genatlas (Paris)C10orf2
WikiGenes56652
SOURCE (Princeton)C10orf2
Genetics Home Reference (NIH)C10orf2
Genomic and cartography
GoldenPath hg19 (UCSC)C10orf2  -     chr10:102747293-102754158 +  10q24.31   [Description]    (hg19-Feb_2009)
GoldenPath hg38 (UCSC)C10orf2  -     10q24.31   [Description]    (hg38-Dec_2013)
EnsemblC10orf2 - 10q24.31 [CytoView hg19]  C10orf2 - 10q24.31 [CytoView hg38]
Mapping of homologs : NCBIC10orf2 [Mapview hg19]  C10orf2 [Mapview hg38]
OMIM271245   606075   607459   609286   616138   
Gene and transcription
Genbank (Entrez)AF292004 AF292005 AK022959 AK025485 AK297068
RefSeq transcript (Entrez)NM_001163812 NM_001163813 NM_001163814 NM_021830
RefSeq genomic (Entrez)NC_000010 NC_018921 NG_012624 NT_030059 NW_004929376
Consensus coding sequences : CCDS (NCBI)C10orf2
Cluster EST : UnigeneHs.22678 [ NCBI ]
CGAP (NCI)Hs.22678
Alternative Splicing GalleryENSG00000107815
Gene ExpressionC10orf2 [ NCBI-GEO ]   C10orf2 [ EBI - ARRAY_EXPRESS ]   C10orf2 [ SEEK ]   C10orf2 [ MEM ]
Gene Expression Viewer (FireBrowse)C10orf2 [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevisibleExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)56652
GTEX Portal (Tissue expression)C10orf2
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ96RR1   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtQ96RR1  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProQ96RR1
Splice isoforms : SwissVarQ96RR1
Catalytic activity : Enzyme3.6.4.12 [ Enzyme-Expasy ]   3.6.4.123.6.4.12 [ IntEnz-EBI ]   3.6.4.12 [ BRENDA ]   3.6.4.12 [ KEGG ]   
PhosPhoSitePlusQ96RR1
Domaine pattern : Prosite (Expaxy)SF4_HELICASE (PS51199)   
Domains : Interpro (EBI)DNA_helicase_DnaB-like_C    P-loop_NTPase    Twinkle-like   
Domain families : Pfam (Sanger)
Domain families : Pfam (NCBI)
Conserved Domain (NCBI)C10orf2
DMDM Disease mutations56652
Blocks (Seattle)C10orf2
SuperfamilyQ96RR1
Human Protein AtlasENSG00000107815
Peptide AtlasQ96RR1
HPRD05830
IPIIPI00102660   IPI00640641   IPI00654621   IPI00943680   IPI00943723   
Protein Interaction databases
DIP (DOE-UCLA)Q96RR1
IntAct (EBI)Q96RR1
FunCoupENSG00000107815
BioGRIDC10orf2
STRING (EMBL)C10orf2
ZODIACC10orf2
Ontologies - Pathways
QuickGOQ96RR1
Ontology : AmiGOprotease binding  single-stranded DNA binding  ATP binding  mitochondrial matrix  mitochondrial DNA replication  mitochondrial DNA replication  DNA unwinding involved in DNA replication  transcription from mitochondrial promoter  mitochondrion organization  protein hexamerization  mitochondrial nucleoid  5'-3' DNA helicase activity  protein homooligomerization  cellular response to glucose stimulus  
Ontology : EGO-EBIprotease binding  single-stranded DNA binding  ATP binding  mitochondrial matrix  mitochondrial DNA replication  mitochondrial DNA replication  DNA unwinding involved in DNA replication  transcription from mitochondrial promoter  mitochondrion organization  protein hexamerization  mitochondrial nucleoid  5'-3' DNA helicase activity  protein homooligomerization  cellular response to glucose stimulus  
NDEx NetworkC10orf2
Atlas of Cancer Signalling NetworkC10orf2
Wikipedia pathwaysC10orf2
Orthology - Evolution
OrthoDB56652
GeneTree (enSembl)ENSG00000107815
Phylogenetic Trees/Animal Genes : TreeFamC10orf2
HOVERGENQ96RR1
HOGENOMQ96RR1
Homologs : HomoloGeneC10orf2
Homology/Alignments : Family Browser (UCSC)C10orf2
Gene fusions - Rearrangements
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerC10orf2 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)C10orf2
dbVarC10orf2
ClinVarC10orf2
1000_GenomesC10orf2 
Exome Variant ServerC10orf2
ExAC (Exome Aggregation Consortium)C10orf2 (select the gene name)
Genetic variants : HAPMAP56652
Genomic Variants (DGV)C10orf2 [DGVbeta]
DECIPHER (Syndromes)10:102747293-102754158  ENSG00000107815
CONAN: Copy Number AnalysisC10orf2 
Mutations
ICGC Data PortalC10orf2 
TCGA Data PortalC10orf2 
Broad Tumor PortalC10orf2
OASIS PortalC10orf2 [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICC10orf2  [overview]  [genome browser]  [tissue]  [distribution]  
Mutations and Diseases : HGMDC10orf2
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD - Leiden Open Variation Database
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
LOVD (Leiden Open Variation Database)MSeqDR-LSDB Mitochondrial Disease Locus Specific Database
BioMutasearch C10orf2
DgiDB (Drug Gene Interaction Database)C10orf2
DoCM (Curated mutations)C10orf2 (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)C10orf2 (select a term)
intoGenC10orf2
Cancer3DC10orf2(select the gene name)
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM271245    606075    607459    609286    616138   
Orphanet
MedgenC10orf2
Genetic Testing Registry C10orf2
NextProtQ96RR1 [Medical]
TSGene56652
GENETestsC10orf2
Huge Navigator C10orf2 [HugePedia]
snp3D : Map Gene to Disease56652
BioCentury BCIQC10orf2
ClinGenC10orf2
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD56652
Chemical/Pharm GKB GenePA162377675
Clinical trialC10orf2
Miscellaneous
canSAR (ICR)C10orf2 (select the gene name)
Probes
Litterature
PubMed78 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineC10orf2
EVEXC10orf2
GoPubMedC10orf2
iHOPC10orf2
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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© Atlas of Genetics and Cytogenetics in Oncology and Haematology
indexed on : Fri Nov 18 19:32:26 CET 2016

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