Atlas of Genetics and Cytogenetics in Oncology and Haematology


Home   Genes   Leukemias   Solid Tumors   Cancer-Prone   Deep Insight   Case Reports   Journals  Portal   Teaching   

X Y 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22 NA

C12orf4 (chromosome 12 open reading frame 4)

Identity

Other alias-
HGNC (Hugo) C12orf4
LocusID (NCBI) 57102
Atlas_Id 54163
Location 12p13.32  [Link to chromosome band 12p13]
Location_base_pair Starts at 4487730 and ends at 4538508 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2016)
C12orf4 (12p13.32) / CD9 (12p13.31)CRACR2A (12p13.32) / C12orf4 (12p13.32)EFCAB4B C12orf4 12p13.32

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


Other Solid tumors implicated (Data extracted from papers in the Atlas) [ 1 ]
  Lung: Translocations in Small Cell Carcinoma


External links

Nomenclature
HGNC (Hugo)C12orf4   1184
Cards
Entrez_Gene (NCBI)C12orf4  57102  chromosome 12 open reading frame 4
Aliases
GeneCards (Weizmann)C12orf4
Ensembl hg19 (Hinxton)ENSG00000047621 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000047621 [Gene_View]  chr12:4487730-4538508 [Contig_View]  C12orf4 [Vega]
ICGC DataPortalENSG00000047621
TCGA cBioPortalC12orf4
AceView (NCBI)C12orf4
Genatlas (Paris)C12orf4
WikiGenes57102
SOURCE (Princeton)C12orf4
Genetics Home Reference (NIH)C12orf4
Genomic and cartography
GoldenPath hg38 (UCSC)C12orf4  -     chr12:4487730-4538508 -  12p13.32   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)C12orf4  -     12p13.32   [Description]    (hg19-Feb_2009)
EnsemblC12orf4 - 12p13.32 [CytoView hg19]  C12orf4 - 12p13.32 [CytoView hg38]
Mapping of homologs : NCBIC12orf4 [Mapview hg19]  C12orf4 [Mapview hg38]
OMIM616082   
Gene and transcription
Genbank (Entrez)AJ272205 AK024811 AK074479 AL834377 BC016908
RefSeq transcript (Entrez)NM_001304811 NM_001346153 NM_001346155 NM_001346156 NM_001346157 NM_020374
RefSeq genomic (Entrez)
Consensus coding sequences : CCDS (NCBI)C12orf4
Cluster EST : UnigeneHs.302977 [ NCBI ]
CGAP (NCI)Hs.302977
Alternative Splicing GalleryENSG00000047621
Gene ExpressionC12orf4 [ NCBI-GEO ]   C12orf4 [ EBI - ARRAY_EXPRESS ]   C12orf4 [ SEEK ]   C12orf4 [ MEM ]
Gene Expression Viewer (FireBrowse)C12orf4 [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevisibleExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)57102
GTEX Portal (Tissue expression)C12orf4
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ9NQ89   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtQ9NQ89  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProQ9NQ89
Splice isoforms : SwissVarQ9NQ89
PhosPhoSitePlusQ9NQ89
Domains : Interpro (EBI)DUF2362   
Domain families : Pfam (Sanger)DUF2362 (PF10154)   
Domain families : Pfam (NCBI)pfam10154   
Conserved Domain (NCBI)C12orf4
DMDM Disease mutations57102
Blocks (Seattle)C12orf4
SuperfamilyQ9NQ89
Human Protein AtlasENSG00000047621
Peptide AtlasQ9NQ89
HPRD12609
IPIIPI00006906   IPI01012154   IPI01010705   IPI01009436   IPI01015049   
Protein Interaction databases
DIP (DOE-UCLA)Q9NQ89
IntAct (EBI)Q9NQ89
FunCoupENSG00000047621
BioGRIDC12orf4
STRING (EMBL)C12orf4
ZODIACC12orf4
Ontologies - Pathways
QuickGOQ9NQ89
Ontology : AmiGOcytoplasm  regulation of mast cell degranulation  
Ontology : EGO-EBIcytoplasm  regulation of mast cell degranulation  
NDEx NetworkC12orf4
Atlas of Cancer Signalling NetworkC12orf4
Wikipedia pathwaysC12orf4
Orthology - Evolution
OrthoDB57102
GeneTree (enSembl)ENSG00000047621
Phylogenetic Trees/Animal Genes : TreeFamC12orf4
HOVERGENQ9NQ89
HOGENOMQ9NQ89
Homologs : HomoloGeneC12orf4
Homology/Alignments : Family Browser (UCSC)C12orf4
Gene fusions - Rearrangements
Fusion : MitelmanC12orf4/CD9 [12p13.32/12p13.31]  
Fusion : MitelmanCRACR2A/C12orf4 [12p13.32/12p13.32]  [t(12;12)(p13;p13)]  
Fusion: TCGAEFCAB4B C12orf4 12p13.32 GBM
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerC12orf4 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)C12orf4
dbVarC12orf4
ClinVarC12orf4
1000_GenomesC12orf4 
Exome Variant ServerC12orf4
ExAC (Exome Aggregation Consortium)C12orf4 (select the gene name)
Genetic variants : HAPMAP57102
Genomic Variants (DGV)C12orf4 [DGVbeta]
DECIPHERC12orf4 [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisC12orf4 
Mutations
ICGC Data PortalC12orf4 
TCGA Data PortalC12orf4 
Broad Tumor PortalC12orf4
OASIS PortalC12orf4 [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICC12orf4  [overview]  [genome browser]  [tissue]  [distribution]  
Mutations and Diseases : HGMDC12orf4
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
BioMutasearch C12orf4
DgiDB (Drug Gene Interaction Database)C12orf4
DoCM (Curated mutations)C12orf4 (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)C12orf4 (select a term)
intoGenC12orf4
Cancer3DC12orf4(select the gene name)
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM616082   
Orphanet
MedgenC12orf4
Genetic Testing Registry C12orf4
NextProtQ9NQ89 [Medical]
TSGene57102
GENETestsC12orf4
Target ValidationC12orf4
Huge Navigator C12orf4 [HugePedia]
snp3D : Map Gene to Disease57102
BioCentury BCIQC12orf4
ClinGenC12orf4
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD57102
Chemical/Pharm GKB GenePA25505
Clinical trialC12orf4
Miscellaneous
canSAR (ICR)C12orf4 (select the gene name)
Probes
Litterature
PubMed6 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineC12orf4
EVEXC12orf4
GoPubMedC12orf4
iHOPC12orf4
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

Search in all EBI   NCBI

© Atlas of Genetics and Cytogenetics in Oncology and Haematology
indexed on : Wed Jun 7 12:25:58 CEST 2017

Home   Genes   Leukemias   Solid Tumors   Cancer-Prone   Deep Insight   Case Reports   Journals  Portal   Teaching   

For comments and suggestions or contributions, please contact us

jlhuret@AtlasGeneticsOncology.org.