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C16orf70 (chromosome 16 open reading frame 70)

Identity

Alias_namesC16orf6
LIN10
chromosome 16 open reading frame 6
Alias_symbol (synonym)lin-10
FLJ12076
Other alias
HGNC (Hugo) C16orf70
LocusID (NCBI) 80262
Atlas_Id 60968
Location 16q22.1  [Link to chromosome band 16q22]
Location_base_pair Starts at 67109893 and ends at 67148544 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2017)		Data from Atlas, Mitelman, Cosmic Fusion, Fusion Cancer, TCGA fusion databases with official HUGO symbols (see references in chromosomal bands)
ABCC6 (16p13.11) / C16orf70 (16q22.1)ARL16 (17q25.3) / C16orf70 (16q22.1)C16orf70 (16q22.1) / CBFB (16q22.1)
SRPK2 (7q22.3) / C16orf70 (16q22.1)ABCC6 C16orf70ARL16 C16orf70

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 

Other Leukemias implicated (Data extracted from papers in the Atlas)

Leukemias TL_t1616p13q22ID2501

External links

Nomenclature
HGNC (Hugo)C16orf70   29564
Cards
Entrez_Gene (NCBI)C16orf70  80262  chromosome 16 open reading frame 70
AliasesC16orf6; LIN10; lin-10
GeneCards (Weizmann)C16orf70
Ensembl hg19 (Hinxton)ENSG00000125149 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000125149 [Gene_View]  ENSG00000125149 [Sequence]  chr16:67109893-67148544 [Contig_View]  C16orf70 [Vega]
ICGC DataPortalENSG00000125149
TCGA cBioPortalC16orf70
AceView (NCBI)C16orf70
Genatlas (Paris)C16orf70
WikiGenes80262
SOURCE (Princeton)C16orf70
Genetics Home Reference (NIH)C16orf70
Genomic and cartography
GoldenPath hg38 (UCSC)C16orf70  -     chr16:67109893-67148544 +  16q22.1   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)C16orf70  -     16q22.1   [Description]    (hg19-Feb_2009)
GoldenPathC16orf70 - 16q22.1 [CytoView hg19]  C16orf70 - 16q22.1 [CytoView hg38]
ImmunoBaseENSG00000125149
Mapping of homologs : NCBIC16orf70 [Mapview hg19]  C16orf70 [Mapview hg38]
Gene and transcription
Genbank (Entrez)AA127668 AF176088 AK022138 AL540304 BC004556
RefSeq transcript (Entrez)NM_001320540 NM_001320541 NM_001320542 NM_001320543 NM_025187
RefSeq genomic (Entrez)
Consensus coding sequences : CCDS (NCBI)C16orf70
Cluster EST : UnigeneHs.744158 [ NCBI ]
CGAP (NCI)Hs.744158
Alternative Splicing GalleryENSG00000125149
Gene ExpressionC16orf70 [ NCBI-GEO ]   C16orf70 [ EBI - ARRAY_EXPRESS ]   C16orf70 [ SEEK ]   C16orf70 [ MEM ]
Gene Expression Viewer (FireBrowse)C16orf70 [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevestigatorExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)80262
GTEX Portal (Tissue expression)C16orf70
Human Protein AtlasENSG00000125149-C16orf70 [pathology]   [cell]   [tissue]
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ9BSU1   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtQ9BSU1  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProQ9BSU1
Splice isoforms : SwissVarQ9BSU1
PhosPhoSitePlusQ9BSU1
Domains : Interpro (EBI)UPF0183   
Domain families : Pfam (Sanger)UPF0183 (PF03676)   
Domain families : Pfam (NCBI)pfam03676   
Conserved Domain (NCBI)C16orf70
DMDM Disease mutations80262
Blocks (Seattle)C16orf70
SuperfamilyQ9BSU1
Human Protein Atlas [tissue]ENSG00000125149-C16orf70 [tissue]
Peptide AtlasQ9BSU1
HPRD17460
IPIIPI00013779   IPI00386924   
Protein Interaction databases
DIP (DOE-UCLA)Q9BSU1
IntAct (EBI)Q9BSU1
FunCoupENSG00000125149
BioGRIDC16orf70
STRING (EMBL)C16orf70
ZODIACC16orf70
Ontologies - Pathways
QuickGOQ9BSU1
Ontology : AmiGOprotein binding  trans-Golgi network  dendrite  synaptic vesicle membrane  Golgi to plasma membrane protein transport  
Ontology : EGO-EBIprotein binding  trans-Golgi network  dendrite  synaptic vesicle membrane  Golgi to plasma membrane protein transport  
NDEx NetworkC16orf70
Atlas of Cancer Signalling NetworkC16orf70
Wikipedia pathwaysC16orf70
Orthology - Evolution
OrthoDB80262
GeneTree (enSembl)ENSG00000125149
Phylogenetic Trees/Animal Genes : TreeFamC16orf70
HOGENOMQ9BSU1
Homologs : HomoloGeneC16orf70
Homology/Alignments : Family Browser (UCSC)C16orf70
Gene fusions - Rearrangements
Fusion PortalABCC6 C16orf70
Fusion PortalARL16 C16orf70
Fusion : QuiverC16orf70
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerC16orf70 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)C16orf70
dbVarC16orf70
ClinVarC16orf70
1000_GenomesC16orf70 
Exome Variant ServerC16orf70
ExAC (Exome Aggregation Consortium)ENSG00000125149
GNOMAD BrowserENSG00000125149
Varsome BrowserC16orf70
Genetic variants : HAPMAP80262
Genomic Variants (DGV)C16orf70 [DGVbeta]
DECIPHERC16orf70 [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisC16orf70 
Mutations
ICGC Data PortalC16orf70 
TCGA Data PortalC16orf70 
Broad Tumor PortalC16orf70
OASIS PortalC16orf70 [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICC16orf70  [overview]  [genome browser]  [tissue]  [distribution]  
Somatic Mutations in Cancer : COSMIC3DC16orf70
Mutations and Diseases : HGMDC16orf70
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD - Leiden Open Variation Database
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
BioMutasearch C16orf70
DgiDB (Drug Gene Interaction Database)C16orf70
DoCM (Curated mutations)C16orf70 (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)C16orf70 (select a term)
intoGenC16orf70
Cancer3DC16orf70(select the gene name)
Impact of mutations[PolyPhen2] [Provean] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM
Orphanet
DisGeNETC16orf70
MedgenC16orf70
Genetic Testing Registry C16orf70
NextProtQ9BSU1 [Medical]
TSGene80262
GENETestsC16orf70
Target ValidationC16orf70
Huge Navigator C16orf70 [HugePedia]
snp3D : Map Gene to Disease80262
BioCentury BCIQC16orf70
ClinGenC16orf70
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD80262
Chemical/Pharm GKB GenePA142671552
Clinical trialC16orf70
Miscellaneous
canSAR (ICR)C16orf70 (select the gene name)
DataMed IndexC16orf70
Probes
Litterature
PubMed17 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineC16orf70
EVEXC16orf70
GoPubMedC16orf70
iHOPC16orf70
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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indexed on : Tue Sep 3 15:21:21 CEST 2019
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