Identity
HGNC
LOCATION
Xq24
LOCUSID
ALIAS
C1GALT2,C38H2-L1,COSMC,HSPC067,MST143,TNPS
FUSION GENES
Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, contribute in submission tool
Other Information
Locus ID:
NCBI: 29071
MIM: 300611
HGNC: 24338
Ensembl: ENSG00000171155
Variants:
dbSNP: 29071
ClinVar: 29071
TCGA: ENSG00000171155
COSMIC: C1GALT1C1
RNA/Proteins
| Gene ID | Transcript ID | Uniprot |
|---|---|---|
| ENSG00000171155 | ENST00000304661 | Q96EU7 |
| ENSG00000171155 | ENST00000371313 | Q96EU7 |
Expression (GTEx)
Pathways
Protein levels (Protein atlas)
References
| Pubmed ID | Year | Title | Citations |
|---|---|---|---|
| 34644263 | 2021 | Cosmc transfection decreases malignant behavior of Tn(+) cells and enhances sensitivity to apoptosis when induced by Apo2L/TRAIL via alteration of O-glycan structure. | 4 |
| 34644263 | 2021 | Cosmc transfection decreases malignant behavior of Tn(+) cells and enhances sensitivity to apoptosis when induced by Apo2L/TRAIL via alteration of O-glycan structure. | 4 |
| 31471227 | 2020 | C1GALT1C1/COSMC is a novel prognostic biomarker for hepatocellular carcinoma. | 2 |
| 31633299 | 2020 | Cosmc overexpression enhances malignancies in human colon cancer. | 8 |
| 32186752 | 2020 | MicroRNA‑196b targets COSMC in pediatric IgA nephropathy. | 3 |
| 31471227 | 2020 | C1GALT1C1/COSMC is a novel prognostic biomarker for hepatocellular carcinoma. | 2 |
| 31633299 | 2020 | Cosmc overexpression enhances malignancies in human colon cancer. | 8 |
| 32186752 | 2020 | MicroRNA‑196b targets COSMC in pediatric IgA nephropathy. | 3 |
| 30115016 | 2018 | Differential expression of Cosmc, T-synthase and mucins in Tn-positive colorectal cancers. | 30 |
| 30115016 | 2018 | Differential expression of Cosmc, T-synthase and mucins in Tn-positive colorectal cancers. | 30 |
| 28035353 | 2017 | TGF-β1 mimics the effect of IL-4 on the glycosylation of IgA1 by downregulating core 1 β1, 3-galactosyltransferase and Cosmc. | 6 |
| 28187132 | 2017 | GWAS for serum galactose-deficient IgA1 implicates critical genes of the O-glycosylation pathway. | 69 |
| 28665962 | 2017 | Biochemical characterization of functional domains of the chaperone Cosmc. | 11 |
| 28708980 | 2017 | CD3/CD28 dynabeads induce expression of tn antigen in human t cells accompanied by hypermethylation of the cosmc promoter. | 3 |
| 28035353 | 2017 | TGF-β1 mimics the effect of IL-4 on the glycosylation of IgA1 by downregulating core 1 β1, 3-galactosyltransferase and Cosmc. | 6 |
Citation
Dessen P
C1GALT1C1 (C1GALT1 specific chaperone 1)
Atlas Genet Cytogenet Oncol Haematol. 2008-07-01
Online version: http://atlasgeneticsoncology.org/gene/50225/c1galt1c1
