Atlas of Genetics and Cytogenetics in Oncology and Haematology


Home   Genes   Leukemias   Solid Tumors   Cancer-Prone   Deep Insight   Case Reports   Journals  Portal   Teaching   

X Y 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22 NA

C1QB (complement C1q B chain)

Identity

Alias_namescomplement component 1, q subcomponent, beta polypeptide
complement component 1, q subcomponent, B chain
complement C1q chain B
Other alias-
HGNC (Hugo) C1QB
LocusID (NCBI) 713
Atlas_Id 52485
Location 1p36.12  [Link to chromosome band 1p36]
Location_base_pair Starts at 22652981 and ends at 22661636 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2016)
CYC1 (8q24.3) / C1QB (1p36.12)

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


External links

Nomenclature
HGNC (Hugo)C1QB   1242
LRG (Locus Reference Genomic)LRG_23
Cards
Entrez_Gene (NCBI)C1QB  713  complement C1q B chain
Aliases
GeneCards (Weizmann)C1QB
Ensembl hg19 (Hinxton)ENSG00000173369 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000173369 [Gene_View]  chr1:22652981-22661636 [Contig_View]  C1QB [Vega]
ICGC DataPortalENSG00000173369
TCGA cBioPortalC1QB
AceView (NCBI)C1QB
Genatlas (Paris)C1QB
WikiGenes713
SOURCE (Princeton)C1QB
Genetics Home Reference (NIH)C1QB
Genomic and cartography
GoldenPath hg38 (UCSC)C1QB  -     chr1:22652981-22661636 +  1p36.12   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)C1QB  -     1p36.12   [Description]    (hg19-Feb_2009)
EnsemblC1QB - 1p36.12 [CytoView hg19]  C1QB - 1p36.12 [CytoView hg38]
Mapping of homologs : NCBIC1QB [Mapview hg19]  C1QB [Mapview hg38]
OMIM120570   613652   
Gene and transcription
Genbank (Entrez)BC008983 BI823081 BQ711602 CA425453 DQ891531
RefSeq transcript (Entrez)NM_000491
RefSeq genomic (Entrez)
Consensus coding sequences : CCDS (NCBI)C1QB
Cluster EST : UnigeneHs.8986 [ NCBI ]
CGAP (NCI)Hs.8986
Alternative Splicing GalleryENSG00000173369
Gene ExpressionC1QB [ NCBI-GEO ]   C1QB [ EBI - ARRAY_EXPRESS ]   C1QB [ SEEK ]   C1QB [ MEM ]
Gene Expression Viewer (FireBrowse)C1QB [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevisibleExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)713
GTEX Portal (Tissue expression)C1QB
Protein : pattern, domain, 3D structure
UniProt/SwissProtP02746   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtP02746  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProP02746
Splice isoforms : SwissVarP02746
PhosPhoSitePlusP02746
Domaine pattern : Prosite (Expaxy)C1Q (PS50871)   
Domains : Interpro (EBI)C1q_dom    Collagen    Tumour_necrosis_fac-like_dom   
Domain families : Pfam (Sanger)C1q (PF00386)    Collagen (PF01391)   
Domain families : Pfam (NCBI)pfam00386    pfam01391   
Domain families : Smart (EMBL)C1Q (SM00110)  
Conserved Domain (NCBI)C1QB
DMDM Disease mutations713
Blocks (Seattle)C1QB
PDB (SRS)1PK6    2JG8    2JG9    2WNU    2WNV    5HKJ    5HZF   
PDB (PDBSum)1PK6    2JG8    2JG9    2WNU    2WNV    5HKJ    5HZF   
PDB (IMB)1PK6    2JG8    2JG9    2WNU    2WNV    5HKJ    5HZF   
PDB (RSDB)1PK6    2JG8    2JG9    2WNU    2WNV    5HKJ    5HZF   
Structural Biology KnowledgeBase1PK6    2JG8    2JG9    2WNU    2WNV    5HKJ    5HZF   
SCOP (Structural Classification of Proteins)1PK6    2JG8    2JG9    2WNU    2WNV    5HKJ    5HZF   
CATH (Classification of proteins structures)1PK6    2JG8    2JG9    2WNU    2WNV    5HKJ    5HZF   
SuperfamilyP02746
Human Protein AtlasENSG00000173369
Peptide AtlasP02746
HPRD00394
IPIIPI00477992   IPI00643948   IPI00964383   
Protein Interaction databases
DIP (DOE-UCLA)P02746
IntAct (EBI)P02746
FunCoupENSG00000173369
BioGRIDC1QB
STRING (EMBL)C1QB
ZODIACC1QB
Ontologies - Pathways
QuickGOP02746
Ontology : AmiGOserine-type endopeptidase activity  protein binding  extracellular region  collagen trimer  complement component C1 complex  proteolysis  complement activation  complement activation, classical pathway  protein homodimerization activity  innate immune response  inner ear development  extracellular exosome  blood microparticle  
Ontology : EGO-EBIserine-type endopeptidase activity  protein binding  extracellular region  collagen trimer  complement component C1 complex  proteolysis  complement activation  complement activation, classical pathway  protein homodimerization activity  innate immune response  inner ear development  extracellular exosome  blood microparticle  
Pathways : BIOCARTAClassical Complement Pathway [Genes]    Complement Pathway [Genes]   
Pathways : KEGGComplement and coagulation cascades    Prion diseases    Pertussis    Chagas disease (American trypanosomiasis)    Staphylococcus aureus infection    Systemic lupus erythematosus   
NDEx NetworkC1QB
Atlas of Cancer Signalling NetworkC1QB
Wikipedia pathwaysC1QB
Orthology - Evolution
OrthoDB713
GeneTree (enSembl)ENSG00000173369
Phylogenetic Trees/Animal Genes : TreeFamC1QB
HOVERGENP02746
HOGENOMP02746
Homologs : HomoloGeneC1QB
Homology/Alignments : Family Browser (UCSC)C1QB
Gene fusions - Rearrangements
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerC1QB [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)C1QB
dbVarC1QB
ClinVarC1QB
1000_GenomesC1QB 
Exome Variant ServerC1QB
ExAC (Exome Aggregation Consortium)C1QB (select the gene name)
Genetic variants : HAPMAP713
Genomic Variants (DGV)C1QB [DGVbeta]
DECIPHERC1QB [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisC1QB 
Mutations
ICGC Data PortalC1QB 
TCGA Data PortalC1QB 
Broad Tumor PortalC1QB
OASIS PortalC1QB [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICC1QB  [overview]  [genome browser]  [tissue]  [distribution]  
Mutations and Diseases : HGMDC1QB
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD - Leiden Open Variation Database
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
LOVD (Leiden Open Variation Database)**PUBLIC** CCHMC Molecular Genetics Laboratory Mutation Database
BioMutasearch C1QB
DgiDB (Drug Gene Interaction Database)C1QB
DoCM (Curated mutations)C1QB (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)C1QB (select a term)
intoGenC1QB
Cancer3DC1QB(select the gene name)
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM120570    613652   
Orphanet17827   
MedgenC1QB
Genetic Testing Registry C1QB
NextProtP02746 [Medical]
TSGene713
GENETestsC1QB
Target ValidationC1QB
Huge Navigator C1QB [HugePedia]
snp3D : Map Gene to Disease713
BioCentury BCIQC1QB
ClinGenC1QB (curated)
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD713
Chemical/Pharm GKB GenePA25623
Clinical trialC1QB
Miscellaneous
canSAR (ICR)C1QB (select the gene name)
Probes
Litterature
PubMed73 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineC1QB
EVEXC1QB
GoPubMedC1QB
iHOPC1QB
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

Search in all EBI   NCBI

© Atlas of Genetics and Cytogenetics in Oncology and Haematology
indexed on : Wed Jun 7 12:26:05 CEST 2017

Home   Genes   Leukemias   Solid Tumors   Cancer-Prone   Deep Insight   Case Reports   Journals  Portal   Teaching   

For comments and suggestions or contributions, please contact us

jlhuret@AtlasGeneticsOncology.org.