C1QTNF1 (C1q and TNF related 1)

2003-06-01  

Identity

HGNC
LOCATION
17q25.3
LOCUSID
ALIAS
CTRP1,GIP,ZSIG37
FUSION GENES

Other Information

Locus ID:

NCBI: 114897
MIM: 610365
HGNC: 14324
Ensembl: ENSG00000173918

Variants:

dbSNP: 114897
ClinVar: 114897
TCGA: ENSG00000173918
COSMIC: C1QTNF1

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000173918ENST00000311661A0A0C4DFP7
ENSG00000173918ENST00000339142Q9BXJ1
ENSG00000173918ENST00000354124Q9BXJ1
ENSG00000173918ENST00000392445Q9BXJ1
ENSG00000173918ENST00000578229A0A0C4DFP7
ENSG00000173918ENST00000579760Q9BXJ1
ENSG00000173918ENST00000580454Q9BXJ1
ENSG00000173918ENST00000580474Q9BXJ1
ENSG00000173918ENST00000581774Q9BXJ1
ENSG00000173918ENST00000583904Q9BXJ1

Expression (GTEx)

0
50
100
150
200
250
300
350
400

Protein levels (Protein atlas)

Not detected
Low
Medium
High

References

Pubmed IDYearTitleCitations
187833462008Molecular, biochemical and functional characterizations of C1q/TNF family members: adipose-tissue-selective expression patterns, regulation by PPAR-gamma agonist, cysteine-mediated oligomerizations, combinatorial associations and metabolic functions.110
188422942008Association between the SERPING1 gene and age-related macular degeneration: a two-stage case-control study.65
181716932008A novel adipokine CTRP1 stimulates aldosterone production.33
168061992006Tumor necrosis factor-alpha and interleukin-1beta increases CTRP1 expression in adipose tissue.14
230003112013Development of a novel enzyme-linked immunosorbent assay (ELISA) for measurement of serum CTRP1: a pilot study: measurement of serum CTRP1 in healthy donors and patients with metabolic syndrome.13
248274302014Circulating complement-C1q TNF-related protein 1 levels are increased in patients with type 2 diabetes and are associated with insulin sensitivity in Chinese subjects.12
163868772006An intracellular role for the C1q-globular domain.9
249451452014Association of circulating C1q/TNF-related protein 1 levels with coronary artery disease in men.9
249652252014Elevated circulating levels of CTRP1, a novel adipokine, in diabetic patients.9
271756102016C1q/TNF-related protein 1 links macrophage lipid metabolism to inflammation and atherosclerosis.7

Citation

Dessen P

C1QTNF1 (C1q and TNF related 1)

Atlas Genet Cytogenet Oncol Haematol. 2003-06-01

Online version: http://atlasgeneticsoncology.org/gene/873/c1qtnf1