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C3AR1 (complement component 3a receptor 1)

Identity

Alias_namescomplement component 3a receptor 1
Alias_symbol (synonym)C3AR
AZ3B
Other aliasHNFAG09
HGNC (Hugo) C3AR1
LocusID (NCBI) 719
Atlas_Id 55773
Location 12p13.31  [Link to chromosome band 12p13]
Location_base_pair Starts at 8210919 and ends at 8218955 bp from pter ( according to hg19-Feb_2009)
Fusion genes
(updated 2016)
C3AR1 (12p13.31) / C3AR1 (12p13.31)

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


External links

Nomenclature
HGNC (Hugo)C3AR1   1319
Cards
Entrez_Gene (NCBI)C3AR1  719  complement component 3a receptor 1
AliasesAZ3B; C3AR; HNFAG09
GeneCards (Weizmann)C3AR1
Ensembl hg19 (Hinxton)ENSG00000171860 [Gene_View]  chr12:8210919-8218955 [Contig_View]  C3AR1 [Vega]
Ensembl hg38 (Hinxton)ENSG00000171860 [Gene_View]  chr12:8210919-8218955 [Contig_View]  C3AR1 [Vega]
ICGC DataPortalENSG00000171860
TCGA cBioPortalC3AR1
AceView (NCBI)C3AR1
Genatlas (Paris)C3AR1
WikiGenes719
SOURCE (Princeton)C3AR1
Genetics Home Reference (NIH)C3AR1
Genomic and cartography
GoldenPath hg19 (UCSC)C3AR1  -     chr12:8210919-8218955 -  12p13.31   [Description]    (hg19-Feb_2009)
GoldenPath hg38 (UCSC)C3AR1  -     12p13.31   [Description]    (hg38-Dec_2013)
EnsemblC3AR1 - 12p13.31 [CytoView hg19]  C3AR1 - 12p13.31 [CytoView hg38]
Mapping of homologs : NCBIC3AR1 [Mapview hg19]  C3AR1 [Mapview hg38]
OMIM605246   
Gene and transcription
Genbank (Entrez)AK223388 AK290242 AK312458 BC020742 BU074964
RefSeq transcript (Entrez)NM_001326475 NM_001326477 NM_004054
RefSeq genomic (Entrez)NC_000012 NC_018923 NT_009714 NW_004929383
Consensus coding sequences : CCDS (NCBI)C3AR1
Cluster EST : UnigeneHs.591148 [ NCBI ]
CGAP (NCI)Hs.591148
Alternative Splicing GalleryENSG00000171860
Gene ExpressionC3AR1 [ NCBI-GEO ]   C3AR1 [ EBI - ARRAY_EXPRESS ]   C3AR1 [ SEEK ]   C3AR1 [ MEM ]
Gene Expression Viewer (FireBrowse)C3AR1 [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevisibleExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)719
GTEX Portal (Tissue expression)C3AR1
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ16581   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtQ16581  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProQ16581
Splice isoforms : SwissVarQ16581
PhosPhoSitePlusQ16581
Domaine pattern : Prosite (Expaxy)G_PROTEIN_RECEP_F1_1 (PS00237)    G_PROTEIN_RECEP_F1_2 (PS50262)   
Domains : Interpro (EBI)Anaphtx_C3AR1    Anphylx_rcpt    Formyl_rcpt-rel    GPCR_Rhodpsn    GPCR_Rhodpsn_7TM   
Domain families : Pfam (Sanger)7tm_1 (PF00001)   
Domain families : Pfam (NCBI)pfam00001   
Conserved Domain (NCBI)C3AR1
DMDM Disease mutations719
Blocks (Seattle)C3AR1
SuperfamilyQ16581
Human Protein AtlasENSG00000171860
Peptide AtlasQ16581
HPRD05581
IPIIPI00293530   IPI01013045   
Protein Interaction databases
DIP (DOE-UCLA)Q16581
IntAct (EBI)Q16581
FunCoupENSG00000171860
BioGRIDC3AR1
STRING (EMBL)C3AR1
ZODIACC3AR1
Ontologies - Pathways
QuickGOQ16581
Ontology : AmiGOcomplement component C3a binding  complement receptor mediated signaling pathway  tolerance induction to nonself antigen  phosphatidylinositol phospholipase C activity  complement component C3a receptor activity  G-protein coupled receptor activity  C3a anaphylatoxin receptor activity  plasma membrane  integral component of plasma membrane  chemotaxis  inflammatory response  G-protein coupled receptor signaling pathway  positive regulation of cytosolic calcium ion concentration  blood circulation  regulation of blood pressure  positive regulation of vascular endothelial growth factor production  positive regulation of macrophage chemotaxis  regulation of complement activation  positive regulation of angiogenesis  positive regulation of smooth muscle cell proliferation  positive regulation of glomerular mesangial cell proliferation  positive regulation of neutrophil chemotaxis  positive regulation of DNA biosynthetic process  
Ontology : EGO-EBIcomplement component C3a binding  complement receptor mediated signaling pathway  tolerance induction to nonself antigen  phosphatidylinositol phospholipase C activity  complement component C3a receptor activity  G-protein coupled receptor activity  C3a anaphylatoxin receptor activity  plasma membrane  integral component of plasma membrane  chemotaxis  inflammatory response  G-protein coupled receptor signaling pathway  positive regulation of cytosolic calcium ion concentration  blood circulation  regulation of blood pressure  positive regulation of vascular endothelial growth factor production  positive regulation of macrophage chemotaxis  regulation of complement activation  positive regulation of angiogenesis  positive regulation of smooth muscle cell proliferation  positive regulation of glomerular mesangial cell proliferation  positive regulation of neutrophil chemotaxis  positive regulation of DNA biosynthetic process  
Pathways : KEGGNeuroactive ligand-receptor interaction    Complement and coagulation cascades    Staphylococcus aureus infection   
NDEx NetworkC3AR1
Atlas of Cancer Signalling NetworkC3AR1
Wikipedia pathwaysC3AR1
Orthology - Evolution
OrthoDB719
GeneTree (enSembl)ENSG00000171860
Phylogenetic Trees/Animal Genes : TreeFamC3AR1
HOVERGENQ16581
HOGENOMQ16581
Homologs : HomoloGeneC3AR1
Homology/Alignments : Family Browser (UCSC)C3AR1
Gene fusions - Rearrangements
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerC3AR1 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)C3AR1
dbVarC3AR1
ClinVarC3AR1
1000_GenomesC3AR1 
Exome Variant ServerC3AR1
ExAC (Exome Aggregation Consortium)C3AR1 (select the gene name)
Genetic variants : HAPMAP719
Genomic Variants (DGV)C3AR1 [DGVbeta]
DECIPHER (Syndromes)12:8210919-8218955  ENSG00000171860
CONAN: Copy Number AnalysisC3AR1 
Mutations
ICGC Data PortalC3AR1 
TCGA Data PortalC3AR1 
Broad Tumor PortalC3AR1
OASIS PortalC3AR1 [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICC3AR1  [overview]  [genome browser]  [tissue]  [distribution]  
Mutations and Diseases : HGMDC3AR1
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
BioMutasearch C3AR1
DgiDB (Drug Gene Interaction Database)C3AR1
DoCM (Curated mutations)C3AR1 (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)C3AR1 (select a term)
intoGenC3AR1
Cancer3DC3AR1(select the gene name)
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM605246   
Orphanet
MedgenC3AR1
Genetic Testing Registry C3AR1
NextProtQ16581 [Medical]
TSGene719
GENETestsC3AR1
Huge Navigator C3AR1 [HugePedia]
snp3D : Map Gene to Disease719
BioCentury BCIQC3AR1
ClinGenC3AR1
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD719
Chemical/Pharm GKB GenePA25898
Clinical trialC3AR1
Miscellaneous
canSAR (ICR)C3AR1 (select the gene name)
Probes
Litterature
PubMed51 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineC3AR1
EVEXC3AR1
GoPubMedC3AR1
iHOPC3AR1
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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indexed on : Tue Mar 14 12:58:14 CET 2017

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