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C4BPB (complement component 4 binding protein beta)

Identity

Alias_namesC4BP
complement component 4-binding protein, beta
Other alias
HGNC (Hugo) C4BPB
LocusID (NCBI) 725
Atlas_Id 61193
Location 1q32.1  [Link to chromosome band 1q32]
Location_base_pair Starts at 207089239 and ends at 207099992 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2016)
C4BPA (1q32.2) / C4BPB (1q32.2)

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


External links

Nomenclature
HGNC (Hugo)C4BPB   1328
Cards
Entrez_Gene (NCBI)C4BPB  725  complement component 4 binding protein beta
AliasesC4BP
GeneCards (Weizmann)C4BPB
Ensembl hg19 (Hinxton)ENSG00000123843 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000123843 [Gene_View]  chr1:207089239-207099992 [Contig_View]  C4BPB [Vega]
ICGC DataPortalENSG00000123843
TCGA cBioPortalC4BPB
AceView (NCBI)C4BPB
Genatlas (Paris)C4BPB
WikiGenes725
SOURCE (Princeton)C4BPB
Genetics Home Reference (NIH)C4BPB
Genomic and cartography
GoldenPath hg38 (UCSC)C4BPB  -     chr1:207089239-207099992 +  1q32.1   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)C4BPB  -     1q32.1   [Description]    (hg19-Feb_2009)
EnsemblC4BPB - 1q32.1 [CytoView hg19]  C4BPB - 1q32.1 [CytoView hg38]
Mapping of homologs : NCBIC4BPB [Mapview hg19]  C4BPB [Mapview hg38]
OMIM120831   
Gene and transcription
Genbank (Entrez)AK092427 AK293379 AK315137 BC005378 BG568018
RefSeq transcript (Entrez)NM_000716 NM_001017364 NM_001017365 NM_001017366 NM_001017367
RefSeq genomic (Entrez)
Consensus coding sequences : CCDS (NCBI)C4BPB
Cluster EST : UnigeneHs.99886 [ NCBI ]
CGAP (NCI)Hs.99886
Alternative Splicing GalleryENSG00000123843
Gene ExpressionC4BPB [ NCBI-GEO ]   C4BPB [ EBI - ARRAY_EXPRESS ]   C4BPB [ SEEK ]   C4BPB [ MEM ]
Gene Expression Viewer (FireBrowse)C4BPB [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevisibleExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)725
GTEX Portal (Tissue expression)C4BPB
Protein : pattern, domain, 3D structure
UniProt/SwissProtP20851   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtP20851  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProP20851
Splice isoforms : SwissVarP20851
PhosPhoSitePlusP20851
Domaine pattern : Prosite (Expaxy)SUSHI (PS50923)   
Domains : Interpro (EBI)Sushi_SCR_CCP_dom   
Domain families : Pfam (Sanger)Sushi (PF00084)   
Domain families : Pfam (NCBI)pfam00084   
Domain families : Smart (EMBL)CCP (SM00032)  
Conserved Domain (NCBI)C4BPB
DMDM Disease mutations725
Blocks (Seattle)C4BPB
SuperfamilyP20851
Human Protein AtlasENSG00000123843
Peptide AtlasP20851
HPRD00404
IPIIPI00025862   IPI00555752   IPI00909469   IPI00643437   
Protein Interaction databases
DIP (DOE-UCLA)P20851
IntAct (EBI)P20851
FunCoupENSG00000123843
BioGRIDC4BPB
STRING (EMBL)C4BPB
ZODIACC4BPB
Ontologies - Pathways
QuickGOP20851
Ontology : AmiGOprotein binding  extracellular region  extracellular space  plasma membrane  complement activation, classical pathway  blood coagulation  regulation of complement activation  other organism cell  innate immune response  positive regulation of protein catabolic process  negative regulation of complement activation, classical pathway  regulation of opsonization  
Ontology : EGO-EBIprotein binding  extracellular region  extracellular space  plasma membrane  complement activation, classical pathway  blood coagulation  regulation of complement activation  other organism cell  innate immune response  positive regulation of protein catabolic process  negative regulation of complement activation, classical pathway  regulation of opsonization  
Pathways : KEGGComplement and coagulation cascades    Pertussis   
NDEx NetworkC4BPB
Atlas of Cancer Signalling NetworkC4BPB
Wikipedia pathwaysC4BPB
Orthology - Evolution
OrthoDB725
GeneTree (enSembl)ENSG00000123843
Phylogenetic Trees/Animal Genes : TreeFamC4BPB
HOVERGENP20851
HOGENOMP20851
Homologs : HomoloGeneC4BPB
Homology/Alignments : Family Browser (UCSC)C4BPB
Gene fusions - Rearrangements
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerC4BPB [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)C4BPB
dbVarC4BPB
ClinVarC4BPB
1000_GenomesC4BPB 
Exome Variant ServerC4BPB
ExAC (Exome Aggregation Consortium)C4BPB (select the gene name)
Genetic variants : HAPMAP725
Genomic Variants (DGV)C4BPB [DGVbeta]
DECIPHERC4BPB [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisC4BPB 
Mutations
ICGC Data PortalC4BPB 
TCGA Data PortalC4BPB 
Broad Tumor PortalC4BPB
OASIS PortalC4BPB [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICC4BPB  [overview]  [genome browser]  [tissue]  [distribution]  
Mutations and Diseases : HGMDC4BPB
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD - Leiden Open Variation Database
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
BioMutasearch C4BPB
DgiDB (Drug Gene Interaction Database)C4BPB
DoCM (Curated mutations)C4BPB (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)C4BPB (select a term)
intoGenC4BPB
Cancer3DC4BPB(select the gene name)
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM120831   
Orphanet
MedgenC4BPB
Genetic Testing Registry C4BPB
NextProtP20851 [Medical]
TSGene725
GENETestsC4BPB
Target ValidationC4BPB
Huge Navigator C4BPB [HugePedia]
snp3D : Map Gene to Disease725
BioCentury BCIQC4BPB
ClinGenC4BPB
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD725
Chemical/Pharm GKB GenePA25908
Clinical trialC4BPB
Miscellaneous
canSAR (ICR)C4BPB (select the gene name)
Probes
Litterature
PubMed40 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineC4BPB
EVEXC4BPB
GoPubMedC4BPB
iHOPC4BPB
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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indexed on : Wed Jun 7 15:41:16 CEST 2017

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