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C6orf106 (chromosome 6 open reading frame 106)

Identity

Alias_symbol (synonym)FLJ22195
dJ391O22.4
Other aliasFP852
HGNC (Hugo) C6orf106
LocusID (NCBI) 64771
Atlas_Id 54178
Location 6p21.31  [Link to chromosome band 6p21]
Location_base_pair Starts at 34587280 and ends at 34696850 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2017)
Data from Atlas, Mitelman, Cosmic Fusion, Fusion Cancer, TCGA fusion databases with official HUGO symbols (see references in chromosomal bands)
C6orf106 (6p21.31) / LRRC1 (6p12.1)C6orf106 (6p21.31) / SORBS2 (4q35.1)C6orf106 (6p21.31) / SPDEF (6p21.31)
FXR1 (3q26.33) / C6orf106 (6p21.31)MIR548O2 (8p12) / C6orf106 (6p21.31)SPDEF (6p21.31) / C6orf106 (6p21.31)
USP5 (12p13.31) / C6orf106 (6p21.31)C6orf106 6p21.31 / LRRC1 6p12.1SPDEF 6p21.31 / C6orf106 6p21.31

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


Other Solid tumors implicated (Data extracted from papers in the Atlas) [ 2 ]
  t(6;6)(p12;p21) C6orf106/LRRC1
SPDEF/C6orf106 (6p21)


External links

Nomenclature
HGNC (Hugo)C6orf106   21215
Cards
Entrez_Gene (NCBI)C6orf106  64771  chromosome 6 open reading frame 106
AliasesFP852; dJ391O22.4
GeneCards (Weizmann)C6orf106
Ensembl hg19 (Hinxton)ENSG00000196821 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000196821 [Gene_View]  ENSG00000196821 [Sequence]  chr6:34587280-34696850 [Contig_View]  C6orf106 [Vega]
ICGC DataPortalENSG00000196821
TCGA cBioPortalC6orf106
AceView (NCBI)C6orf106
Genatlas (Paris)C6orf106
WikiGenes64771
SOURCE (Princeton)C6orf106
Genetics Home Reference (NIH)C6orf106
Genomic and cartography
GoldenPath hg38 (UCSC)C6orf106  -     chr6:34587280-34696850 -  6p21.31   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)C6orf106  -     6p21.31   [Description]    (hg19-Feb_2009)
EnsemblC6orf106 - 6p21.31 [CytoView hg19]  C6orf106 - 6p21.31 [CytoView hg38]
Mapping of homologs : NCBIC6orf106 [Mapview hg19]  C6orf106 [Mapview hg38]
OMIM612217   
Gene and transcription
Genbank (Entrez)AF052106 AF370387 AI469525 AK025848 AK056964
RefSeq transcript (Entrez)NM_022758 NM_024294
RefSeq genomic (Entrez)
Consensus coding sequences : CCDS (NCBI)C6orf106
Cluster EST : UnigeneHs.716193 [ NCBI ]
CGAP (NCI)Hs.716193
Alternative Splicing GalleryENSG00000196821
Gene ExpressionC6orf106 [ NCBI-GEO ]   C6orf106 [ EBI - ARRAY_EXPRESS ]   C6orf106 [ SEEK ]   C6orf106 [ MEM ]
Gene Expression Viewer (FireBrowse)C6orf106 [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevestigatorExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)64771
GTEX Portal (Tissue expression)C6orf106
Human Protein AtlasENSG00000196821-C6orf106 [pathology]   [cell]   [tissue]
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ9H6K1   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtQ9H6K1  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProQ9H6K1
Splice isoforms : SwissVarQ9H6K1
PhosPhoSitePlusQ9H6K1
Domains : Interpro (EBI)Ig-like_fold    N_BRCA1_central    UBA-like_sf   
Domain families : Pfam (Sanger)N_BRCA1_IG (PF16158)   
Domain families : Pfam (NCBI)pfam16158   
Conserved Domain (NCBI)C6orf106
DMDM Disease mutations64771
Blocks (Seattle)C6orf106
SuperfamilyQ9H6K1
Human Protein Atlas [tissue]ENSG00000196821-C6orf106 [tissue]
Peptide AtlasQ9H6K1
HPRD12837
IPIIPI00013269   IPI00332642   IPI00435958   IPI00921603   IPI00642125   
Protein Interaction databases
DIP (DOE-UCLA)Q9H6K1
IntAct (EBI)Q9H6K1
FunCoupENSG00000196821
BioGRIDC6orf106
STRING (EMBL)C6orf106
ZODIACC6orf106
Ontologies - Pathways
QuickGOQ9H6K1
Ontology : AmiGOphagophore assembly site  molecular_function  cellular_component  autophagosome  biological_process  macroautophagy  ubiquitin binding  
Ontology : EGO-EBIphagophore assembly site  molecular_function  cellular_component  autophagosome  biological_process  macroautophagy  ubiquitin binding  
NDEx NetworkC6orf106
Atlas of Cancer Signalling NetworkC6orf106
Wikipedia pathwaysC6orf106
Orthology - Evolution
OrthoDB64771
GeneTree (enSembl)ENSG00000196821
Phylogenetic Trees/Animal Genes : TreeFamC6orf106
HOVERGENQ9H6K1
HOGENOMQ9H6K1
Homologs : HomoloGeneC6orf106
Homology/Alignments : Family Browser (UCSC)C6orf106
Gene fusions - Rearrangements
Fusion : MitelmanC6orf106/LRRC1 [6p21.31/6p12.1]  
Fusion : MitelmanC6orf106/SPDEF [6p21.31/6p21.31]  [t(6;6)(p21;p21)]  
Fusion : MitelmanSPDEF/C6orf106 [6p21.31/6p21.31]  [t(6;6)(p21;p21)]  
Fusion PortalC6orf106 6p21.31 LRRC1 6p12.1 KIRC
Fusion PortalSPDEF 6p21.31 C6orf106 6p21.31 BRCA
Fusion : QuiverC6orf106
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerC6orf106 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)C6orf106
dbVarC6orf106
ClinVarC6orf106
1000_GenomesC6orf106 
Exome Variant ServerC6orf106
ExAC (Exome Aggregation Consortium)ENSG00000196821
GNOMAD BrowserENSG00000196821
Varsome BrowserC6orf106
Genetic variants : HAPMAP64771
Genomic Variants (DGV)C6orf106 [DGVbeta]
DECIPHERC6orf106 [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisC6orf106 
Mutations
ICGC Data PortalC6orf106 
TCGA Data PortalC6orf106 
Broad Tumor PortalC6orf106
OASIS PortalC6orf106 [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICC6orf106  [overview]  [genome browser]  [tissue]  [distribution]  
Mutations and Diseases : HGMDC6orf106
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD - Leiden Open Variation Database
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
BioMutasearch C6orf106
DgiDB (Drug Gene Interaction Database)C6orf106
DoCM (Curated mutations)C6orf106 (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)C6orf106 (select a term)
intoGenC6orf106
Cancer3DC6orf106(select the gene name)
Impact of mutations[PolyPhen2] [Provean] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM612217   
Orphanet
DisGeNETC6orf106
MedgenC6orf106
Genetic Testing Registry C6orf106
NextProtQ9H6K1 [Medical]
TSGene64771
GENETestsC6orf106
Target ValidationC6orf106
Huge Navigator C6orf106 [HugePedia]
snp3D : Map Gene to Disease64771
BioCentury BCIQC6orf106
ClinGenC6orf106
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD64771
Chemical/Pharm GKB GenePA134935866
Clinical trialC6orf106
Miscellaneous
canSAR (ICR)C6orf106 (select the gene name)
Probes
Litterature
PubMed33 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineC6orf106
EVEXC6orf106
GoPubMedC6orf106
iHOPC6orf106
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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© Atlas of Genetics and Cytogenetics in Oncology and Haematology
indexed on : Tue Nov 6 10:55:08 CET 2018

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