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C6orf58 (chromosome 6 open reading frame 58)

Identity

Alias_symbol (synonym)LEG1
Other alias
HGNC (Hugo) C6orf58
LocusID (NCBI) 352999
Atlas_Id 61252
Location 6q22.33  [Link to chromosome band 6q22]
Location_base_pair Starts at 127577174 and ends at 127591818 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2017)
Data from Atlas, Mitelman, Cosmic Fusion, Fusion Cancer, TCGA fusion databases with official HUGO symbols (see references in chromosomal bands)

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


External links

Nomenclature
HGNC (Hugo)C6orf58   20960
Cards
Entrez_Gene (NCBI)C6orf58  352999  chromosome 6 open reading frame 58
AliasesLEG1
GeneCards (Weizmann)C6orf58
Ensembl hg19 (Hinxton)ENSG00000184530 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000184530 [Gene_View]  ENSG00000184530 [Sequence]  chr6:127577174-127591818 [Contig_View]  C6orf58 [Vega]
ICGC DataPortalENSG00000184530
TCGA cBioPortalC6orf58
AceView (NCBI)C6orf58
Genatlas (Paris)C6orf58
WikiGenes352999
SOURCE (Princeton)C6orf58
Genetics Home Reference (NIH)C6orf58
Genomic and cartography
GoldenPath hg38 (UCSC)C6orf58  -     chr6:127577174-127591818 +  6q22.33   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)C6orf58  -     6q22.33   [Description]    (hg19-Feb_2009)
EnsemblC6orf58 - 6q22.33 [CytoView hg19]  C6orf58 - 6q22.33 [CytoView hg38]
Mapping of homologs : NCBIC6orf58 [Mapview hg19]  C6orf58 [Mapview hg38]
Gene and transcription
Genbank (Entrez)AK303850 BC062712
RefSeq transcript (Entrez)NM_001010905
RefSeq genomic (Entrez)
Consensus coding sequences : CCDS (NCBI)C6orf58
Cluster EST : UnigeneHs.226268 [ NCBI ]
CGAP (NCI)Hs.226268
Alternative Splicing GalleryENSG00000184530
Gene ExpressionC6orf58 [ NCBI-GEO ]   C6orf58 [ EBI - ARRAY_EXPRESS ]   C6orf58 [ SEEK ]   C6orf58 [ MEM ]
Gene Expression Viewer (FireBrowse)C6orf58 [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevestigatorExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)352999
GTEX Portal (Tissue expression)C6orf58
Human Protein AtlasENSG00000184530-C6orf58 [pathology]   [cell]   [tissue]
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ6P5S2   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtQ6P5S2  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProQ6P5S2
Splice isoforms : SwissVarQ6P5S2
PhosPhoSitePlusQ6P5S2
Domains : Interpro (EBI)Leg1   
Domain families : Pfam (Sanger)DUF781 (PF05612)   
Domain families : Pfam (NCBI)pfam05612   
Conserved Domain (NCBI)C6orf58
DMDM Disease mutations352999
Blocks (Seattle)C6orf58
SuperfamilyQ6P5S2
Human Protein Atlas [tissue]ENSG00000184530-C6orf58 [tissue]
Peptide AtlasQ6P5S2
HPRD17379
IPIIPI00374315   
Protein Interaction databases
DIP (DOE-UCLA)Q6P5S2
IntAct (EBI)Q6P5S2
FunCoupENSG00000184530
BioGRIDC6orf58
STRING (EMBL)C6orf58
ZODIACC6orf58
Ontologies - Pathways
QuickGOQ6P5S2
Ontology : AmiGOextracellular space  multicellular organism development  extracellular exosome  
Ontology : EGO-EBIextracellular space  multicellular organism development  extracellular exosome  
NDEx NetworkC6orf58
Atlas of Cancer Signalling NetworkC6orf58
Wikipedia pathwaysC6orf58
Orthology - Evolution
OrthoDB352999
GeneTree (enSembl)ENSG00000184530
Phylogenetic Trees/Animal Genes : TreeFamC6orf58
HOVERGENQ6P5S2
HOGENOMQ6P5S2
Homologs : HomoloGeneC6orf58
Homology/Alignments : Family Browser (UCSC)C6orf58
Gene fusions - Rearrangements
Fusion : QuiverC6orf58
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerC6orf58 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)C6orf58
dbVarC6orf58
ClinVarC6orf58
1000_GenomesC6orf58 
Exome Variant ServerC6orf58
ExAC (Exome Aggregation Consortium)ENSG00000184530
GNOMAD BrowserENSG00000184530
Varsome BrowserC6orf58
Genetic variants : HAPMAP352999
Genomic Variants (DGV)C6orf58 [DGVbeta]
DECIPHERC6orf58 [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisC6orf58 
Mutations
ICGC Data PortalC6orf58 
TCGA Data PortalC6orf58 
Broad Tumor PortalC6orf58
OASIS PortalC6orf58 [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICC6orf58  [overview]  [genome browser]  [tissue]  [distribution]  
Mutations and Diseases : HGMDC6orf58
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
BioMutasearch C6orf58
DgiDB (Drug Gene Interaction Database)C6orf58
DoCM (Curated mutations)C6orf58 (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)C6orf58 (select a term)
intoGenC6orf58
Cancer3DC6orf58(select the gene name)
Impact of mutations[PolyPhen2] [Provean] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM
Orphanet
DisGeNETC6orf58
MedgenC6orf58
Genetic Testing Registry C6orf58
NextProtQ6P5S2 [Medical]
TSGene352999
GENETestsC6orf58
Target ValidationC6orf58
Huge Navigator C6orf58 [HugePedia]
snp3D : Map Gene to Disease352999
BioCentury BCIQC6orf58
ClinGenC6orf58
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD352999
Chemical/Pharm GKB GenePA134881952
Clinical trialC6orf58
Miscellaneous
canSAR (ICR)C6orf58 (select the gene name)
Probes
Litterature
PubMed7 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineC6orf58
EVEXC6orf58
GoPubMedC6orf58
iHOPC6orf58
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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indexed on : Mon Jul 30 13:38:40 CEST 2018

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