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C6orf89 (chromosome 6 open reading frame 89)

Identity

Alias_symbol (synonym)FLJ25357
BRAP
Other aliasPS1TP5TP1
HGNC (Hugo) C6orf89
LocusID (NCBI) 221477
Atlas_Id 55991
Location 6p21.2  [Link to chromosome band 6p21]
Location_base_pair Starts at 36885864 and ends at 36928964 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2017)
Data from Atlas, Mitelman, Cosmic Fusion, Fusion Cancer, TCGA fusion databases with official HUGO symbols (see references in chromosomal bands)
C6orf89 (6p21.2) / C6orf89 (6p21.2)C6orf89 (6p21.2) / SH3PXD2A (10q24.33)CCND3 (6p21.1) / C6orf89 (6p21.2)
CDKAL1 (6p22.3) / C6orf89 (6p21.2)LRRC75A-AS1 (17p11.2) / C6orf89 (6p21.2)MPHOSPH9 (12q24.31) / C6orf89 (6p21.2)
SLTM (15q22.1) / C6orf89 (6p21.2)

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


Other Solid tumors implicated (Data extracted from papers in the Atlas) [ 3 ]
  CCND3/C6orf89 (6p21)
t(6;6)(p21;p22) CDKAL1/C6orf89
t(6;12)(p21;q24) MPHOSPH9/C6orf89


External links

Nomenclature
HGNC (Hugo)C6orf89   21114
Cards
Entrez_Gene (NCBI)C6orf89  221477  chromosome 6 open reading frame 89
AliasesBRAP; PS1TP5TP1
GeneCards (Weizmann)C6orf89
Ensembl hg19 (Hinxton)ENSG00000198663 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000198663 [Gene_View]  ENSG00000198663 [Sequence]  chr6:36885864-36928964 [Contig_View]  C6orf89 [Vega]
ICGC DataPortalENSG00000198663
TCGA cBioPortalC6orf89
AceView (NCBI)C6orf89
Genatlas (Paris)C6orf89
WikiGenes221477
SOURCE (Princeton)C6orf89
Genetics Home Reference (NIH)C6orf89
Genomic and cartography
GoldenPath hg38 (UCSC)C6orf89  -     chr6:36885864-36928964 +  6p21.2   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)C6orf89  -     6p21.2   [Description]    (hg19-Feb_2009)
EnsemblC6orf89 - 6p21.2 [CytoView hg19]  C6orf89 - 6p21.2 [CytoView hg38]
Mapping of homologs : NCBIC6orf89 [Mapview hg19]  C6orf89 [Mapview hg38]
OMIM616642   
Gene and transcription
Genbank (Entrez)AJ420498 AJ420511 AK001957 AK025213 AK058086
RefSeq transcript (Entrez)NM_001286635 NM_001286636 NM_001286637 NM_152734
RefSeq genomic (Entrez)
Consensus coding sequences : CCDS (NCBI)C6orf89
Cluster EST : UnigeneHs.433381 [ NCBI ]
CGAP (NCI)Hs.433381
Alternative Splicing GalleryENSG00000198663
Gene ExpressionC6orf89 [ NCBI-GEO ]   C6orf89 [ EBI - ARRAY_EXPRESS ]   C6orf89 [ SEEK ]   C6orf89 [ MEM ]
Gene Expression Viewer (FireBrowse)C6orf89 [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevestigatorExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)221477
GTEX Portal (Tissue expression)C6orf89
Human Protein AtlasENSG00000198663-C6orf89 [pathology]   [cell]   [tissue]
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ6UWU4   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtQ6UWU4  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProQ6UWU4
Splice isoforms : SwissVarQ6UWU4
PhosPhoSitePlusQ6UWU4
Domain families : Pfam (Sanger)
Domain families : Pfam (NCBI)
Conserved Domain (NCBI)C6orf89
DMDM Disease mutations221477
Blocks (Seattle)C6orf89
SuperfamilyQ6UWU4
Human Protein Atlas [tissue]ENSG00000198663-C6orf89 [tissue]
Peptide AtlasQ6UWU4
HPRD12905
IPIIPI00477187   IPI00465226   IPI00761126   IPI00641641   IPI00514182   
Protein Interaction databases
DIP (DOE-UCLA)Q6UWU4
IntAct (EBI)Q6UWU4
FunCoupENSG00000198663
BioGRIDC6orf89
STRING (EMBL)C6orf89
ZODIACC6orf89
Ontologies - Pathways
QuickGOQ6UWU4
Ontology : AmiGOGolgi membrane  protein binding  nucleolus  cytoplasm  plasma membrane  integral component of membrane  midbody  wound healing  positive regulation of cell cycle  epithelial cell proliferation  positive regulation of histone deacetylase activity  
Ontology : EGO-EBIGolgi membrane  protein binding  nucleolus  cytoplasm  plasma membrane  integral component of membrane  midbody  wound healing  positive regulation of cell cycle  epithelial cell proliferation  positive regulation of histone deacetylase activity  
NDEx NetworkC6orf89
Atlas of Cancer Signalling NetworkC6orf89
Wikipedia pathwaysC6orf89
Orthology - Evolution
OrthoDB221477
GeneTree (enSembl)ENSG00000198663
Phylogenetic Trees/Animal Genes : TreeFamC6orf89
HOVERGENQ6UWU4
HOGENOMQ6UWU4
Homologs : HomoloGeneC6orf89
Homology/Alignments : Family Browser (UCSC)C6orf89
Gene fusions - Rearrangements
Fusion : QuiverC6orf89
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerC6orf89 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)C6orf89
dbVarC6orf89
ClinVarC6orf89
1000_GenomesC6orf89 
Exome Variant ServerC6orf89
ExAC (Exome Aggregation Consortium)ENSG00000198663
GNOMAD BrowserENSG00000198663
Varsome BrowserC6orf89
Genetic variants : HAPMAP221477
Genomic Variants (DGV)C6orf89 [DGVbeta]
DECIPHERC6orf89 [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisC6orf89 
Mutations
ICGC Data PortalC6orf89 
TCGA Data PortalC6orf89 
Broad Tumor PortalC6orf89
OASIS PortalC6orf89 [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICC6orf89  [overview]  [genome browser]  [tissue]  [distribution]  
Mutations and Diseases : HGMDC6orf89
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD - Leiden Open Variation Database
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
BioMutasearch C6orf89
DgiDB (Drug Gene Interaction Database)C6orf89
DoCM (Curated mutations)C6orf89 (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)C6orf89 (select a term)
intoGenC6orf89
Cancer3DC6orf89(select the gene name)
Impact of mutations[PolyPhen2] [Provean] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM616642   
Orphanet
DisGeNETC6orf89
MedgenC6orf89
Genetic Testing Registry C6orf89
NextProtQ6UWU4 [Medical]
TSGene221477
GENETestsC6orf89
Target ValidationC6orf89
Huge Navigator C6orf89 [HugePedia]
snp3D : Map Gene to Disease221477
BioCentury BCIQC6orf89
ClinGenC6orf89
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD221477
Chemical/Pharm GKB GenePA134986915
Clinical trialC6orf89
Miscellaneous
canSAR (ICR)C6orf89 (select the gene name)
Probes
Litterature
PubMed19 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineC6orf89
EVEXC6orf89
GoPubMedC6orf89
iHOPC6orf89
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

Search in all EBI   NCBI

© Atlas of Genetics and Cytogenetics in Oncology and Haematology
indexed on : Tue Nov 6 10:55:09 CET 2018

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