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C8G (complement C8 gamma chain)

Identity

Alias_namescomplement component 8, gamma polypeptide
Other aliasC8C
HGNC (Hugo) C8G
LocusID (NCBI) 733
Atlas_Id 61279
Location 9q34.3  [Link to chromosome band 9q34]
Location_base_pair Starts at 136945246 and ends at 136946974 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2017)
Data from Atlas, Mitelman, Cosmic Fusion, Fusion Cancer, TCGA fusion databases with official HUGO symbols (see references in chromosomal bands)

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


External links

Nomenclature
HGNC (Hugo)C8G   1354
Cards
Entrez_Gene (NCBI)C8G  733  complement C8 gamma chain
AliasesC8C
GeneCards (Weizmann)C8G
Ensembl hg19 (Hinxton)ENSG00000176919 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000176919 [Gene_View]  chr9:136945246-136946974 [Contig_View]  C8G [Vega]
ICGC DataPortalENSG00000176919
TCGA cBioPortalC8G
AceView (NCBI)C8G
Genatlas (Paris)C8G
WikiGenes733
SOURCE (Princeton)C8G
Genetics Home Reference (NIH)C8G
Genomic and cartography
GoldenPath hg38 (UCSC)C8G  -     chr9:136945246-136946974 +  9q34.3   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)C8G  -     9q34.3   [Description]    (hg19-Feb_2009)
EnsemblC8G - 9q34.3 [CytoView hg19]  C8G - 9q34.3 [CytoView hg38]
Mapping of homologs : NCBIC8G [Mapview hg19]  C8G [Mapview hg38]
OMIM120930   
Gene and transcription
Genbank (Entrez)AW663384 BC113624 BC113626 BM852158 BX282392
RefSeq transcript (Entrez)NM_000606
RefSeq genomic (Entrez)
Consensus coding sequences : CCDS (NCBI)C8G
Cluster EST : UnigeneHs.1285 [ NCBI ]
CGAP (NCI)Hs.1285
Alternative Splicing GalleryENSG00000176919
Gene ExpressionC8G [ NCBI-GEO ]   C8G [ EBI - ARRAY_EXPRESS ]   C8G [ SEEK ]   C8G [ MEM ]
Gene Expression Viewer (FireBrowse)C8G [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevestigatorExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)733
GTEX Portal (Tissue expression)C8G
Human Protein AtlasENSG00000176919-C8G [pathology]   [cell]   [tissue]
Protein : pattern, domain, 3D structure
UniProt/SwissProtP07360   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtP07360  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProP07360
Splice isoforms : SwissVarP07360
PhosPhoSitePlusP07360
Domaine pattern : Prosite (Expaxy)LIPOCALIN (PS00213)   
Domains : Interpro (EBI)A1-microglobln    Calycin    Calycin-like    Lipocalin    Lipocalin_CS    Lipocln_cytosolic_FA-bd_dom   
Domain families : Pfam (Sanger)Lipocalin (PF00061)   
Domain families : Pfam (NCBI)pfam00061   
Conserved Domain (NCBI)C8G
DMDM Disease mutations733
Blocks (Seattle)C8G
PDB (SRS)1IW2    1LF7    2OVA    2OVD    2OVE    2QOS    2RD7    3OJY   
PDB (PDBSum)1IW2    1LF7    2OVA    2OVD    2OVE    2QOS    2RD7    3OJY   
PDB (IMB)1IW2    1LF7    2OVA    2OVD    2OVE    2QOS    2RD7    3OJY   
PDB (RSDB)1IW2    1LF7    2OVA    2OVD    2OVE    2QOS    2RD7    3OJY   
Structural Biology KnowledgeBase1IW2    1LF7    2OVA    2OVD    2OVE    2QOS    2RD7    3OJY   
SCOP (Structural Classification of Proteins)1IW2    1LF7    2OVA    2OVD    2OVE    2QOS    2RD7    3OJY   
CATH (Classification of proteins structures)1IW2    1LF7    2OVA    2OVD    2OVE    2QOS    2RD7    3OJY   
SuperfamilyP07360
Human Protein Atlas [tissue]ENSG00000176919-C8G [tissue]
Peptide AtlasP07360
HPRD00407
IPIIPI00011261   IPI00513935   
Protein Interaction databases
DIP (DOE-UCLA)P07360
IntAct (EBI)P07360
FunCoupENSG00000176919
BioGRIDC8G
STRING (EMBL)C8G
ZODIACC8G
Ontologies - Pathways
QuickGOP07360
Ontology : AmiGOcomplement binding  extracellular region  membrane attack complex  complement activation, alternative pathway  complement activation, classical pathway  cytolysis  retinol binding  regulation of complement activation  protein complex binding  extracellular exosome  blood microparticle  
Ontology : EGO-EBIcomplement binding  extracellular region  membrane attack complex  complement activation, alternative pathway  complement activation, classical pathway  cytolysis  retinol binding  regulation of complement activation  protein complex binding  extracellular exosome  blood microparticle  
Pathways : KEGGComplement and coagulation cascades    Prion diseases    Amoebiasis    Systemic lupus erythematosus   
NDEx NetworkC8G
Atlas of Cancer Signalling NetworkC8G
Wikipedia pathwaysC8G
Orthology - Evolution
OrthoDB733
GeneTree (enSembl)ENSG00000176919
Phylogenetic Trees/Animal Genes : TreeFamC8G
HOVERGENP07360
HOGENOMP07360
Homologs : HomoloGeneC8G
Homology/Alignments : Family Browser (UCSC)C8G
Gene fusions - Rearrangements
Tumor Fusion PortalC8G
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerC8G [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)C8G
dbVarC8G
ClinVarC8G
1000_GenomesC8G 
Exome Variant ServerC8G
ExAC (Exome Aggregation Consortium)ENSG00000176919
GNOMAD BrowserENSG00000176919
Genetic variants : HAPMAP733
Genomic Variants (DGV)C8G [DGVbeta]
DECIPHERC8G [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisC8G 
Mutations
ICGC Data PortalC8G 
TCGA Data PortalC8G 
Broad Tumor PortalC8G
OASIS PortalC8G [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICC8G  [overview]  [genome browser]  [tissue]  [distribution]  
Mutations and Diseases : HGMDC8G
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD - Leiden Open Variation Database
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
BioMutasearch C8G
DgiDB (Drug Gene Interaction Database)C8G
DoCM (Curated mutations)C8G (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)C8G (select a term)
intoGenC8G
Cancer3DC8G(select the gene name)
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM120930   
Orphanet17828   
DisGeNETC8G
MedgenC8G
Genetic Testing Registry C8G
NextProtP07360 [Medical]
TSGene733
GENETestsC8G
Target ValidationC8G
Huge Navigator C8G [HugePedia]
snp3D : Map Gene to Disease733
BioCentury BCIQC8G
ClinGenC8G
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD733
Chemical/Pharm GKB GenePA25953
Clinical trialC8G
Miscellaneous
canSAR (ICR)C8G (select the gene name)
Probes
Litterature
PubMed28 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineC8G
EVEXC8G
GoPubMedC8G
iHOPC8G
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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© Atlas of Genetics and Cytogenetics in Oncology and Haematology
indexed on : Mon Nov 20 19:22:03 CET 2017

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