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C8orf4 (chromosome 8 open reading frame 4)

Identity

Alias_symbol (synonym)TC-1
hTC-1
TC1
Other alias
HGNC (Hugo) C8orf4
LocusID (NCBI) 56892
Atlas_Id 46518
Location 8p11.21  [Link to chromosome band 8p11]
Location_base_pair Starts at 40153468 and ends at 40155308 bp from pter ( according to hg38-Dec_2013)

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


External links

Nomenclature
HGNC (Hugo)C8orf4   1357
Cards
Entrez_Gene (NCBI)C8orf4  56892  chromosome 8 open reading frame 4
AliasesTC-1; TC1
GeneCards (Weizmann)C8orf4
Ensembl hg19 (Hinxton)ENSG00000176907 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000176907 [Gene_View]  chr8:40153468-40155308 [Contig_View]  C8orf4 [Vega]
ICGC DataPortalENSG00000176907
TCGA cBioPortalC8orf4
AceView (NCBI)C8orf4
Genatlas (Paris)C8orf4
WikiGenes56892
SOURCE (Princeton)C8orf4
Genetics Home Reference (NIH)C8orf4
Genomic and cartography
GoldenPath hg38 (UCSC)C8orf4  -     chr8:40153468-40155308 +  8p11.21   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)C8orf4  -     8p11.21   [Description]    (hg19-Feb_2009)
EnsemblC8orf4 - 8p11.21 [CytoView hg19]  C8orf4 - 8p11.21 [CytoView hg38]
Mapping of homologs : NCBIC8orf4 [Mapview hg19]  C8orf4 [Mapview hg38]
OMIM607702   
Gene and transcription
Genbank (Entrez)AF268037 AI861861 AI935347 AK026240 BC020623
RefSeq transcript (Entrez)NM_020130
RefSeq genomic (Entrez)
Consensus coding sequences : CCDS (NCBI)C8orf4
Cluster EST : UnigeneHs.745031 [ NCBI ]
CGAP (NCI)Hs.745031
Alternative Splicing GalleryENSG00000176907
Gene ExpressionC8orf4 [ NCBI-GEO ]   C8orf4 [ EBI - ARRAY_EXPRESS ]   C8orf4 [ SEEK ]   C8orf4 [ MEM ]
Gene Expression Viewer (FireBrowse)C8orf4 [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevisibleExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)56892
GTEX Portal (Tissue expression)C8orf4
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ9NR00   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtQ9NR00  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProQ9NR00
Splice isoforms : SwissVarQ9NR00
PhosPhoSitePlusQ9NR00
Domains : Interpro (EBI)Avpi1/C8orf4   
Domain families : Pfam (Sanger)TC1 (PF15063)   
Domain families : Pfam (NCBI)pfam15063   
Domain structure : Prodom (Prabi Lyon)Arg_vasopressin-induced_prot_1 (PD287216)   
Conserved Domain (NCBI)C8orf4
DMDM Disease mutations56892
Blocks (Seattle)C8orf4
SuperfamilyQ9NR00
Human Protein AtlasENSG00000176907
Peptide AtlasQ9NR00
HPRD09650
IPIIPI00024500   
Protein Interaction databases
DIP (DOE-UCLA)Q9NR00
IntAct (EBI)Q9NR00
FunCoupENSG00000176907
BioGRIDC8orf4
STRING (EMBL)C8orf4
ZODIACC8orf4
Ontologies - Pathways
QuickGOQ9NR00
Ontology : AmiGOendothelial cell activation involved in immune response  Notch binding  protein binding  intracellular  nucleus  nucleoplasm  nucleolus  cytoplasm  cytosol  plasma membrane  apoptotic process  positive regulation of protein kinase A signaling  nuclear speck  cellular response to heat  positive regulation of NF-kappaB import into nucleus  negative regulation of apoptotic process  regulation of DNA-templated transcription in response to stress  negative regulation of Notch signaling pathway  positive regulation of protein kinase C activity  regulation of cell cycle G1/S phase transition  regulation of hemopoiesis  
Ontology : EGO-EBIendothelial cell activation involved in immune response  Notch binding  protein binding  intracellular  nucleus  nucleoplasm  nucleolus  cytoplasm  cytosol  plasma membrane  apoptotic process  positive regulation of protein kinase A signaling  nuclear speck  cellular response to heat  positive regulation of NF-kappaB import into nucleus  negative regulation of apoptotic process  regulation of DNA-templated transcription in response to stress  negative regulation of Notch signaling pathway  positive regulation of protein kinase C activity  regulation of cell cycle G1/S phase transition  regulation of hemopoiesis  
NDEx NetworkC8orf4
Atlas of Cancer Signalling NetworkC8orf4
Wikipedia pathwaysC8orf4
Orthology - Evolution
OrthoDB56892
GeneTree (enSembl)ENSG00000176907
Phylogenetic Trees/Animal Genes : TreeFamC8orf4
HOVERGENQ9NR00
HOGENOMQ9NR00
Homologs : HomoloGeneC8orf4
Homology/Alignments : Family Browser (UCSC)C8orf4
Gene fusions - Rearrangements
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerC8orf4 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)C8orf4
dbVarC8orf4
ClinVarC8orf4
1000_GenomesC8orf4 
Exome Variant ServerC8orf4
ExAC (Exome Aggregation Consortium)C8orf4 (select the gene name)
Genetic variants : HAPMAP56892
Genomic Variants (DGV)C8orf4 [DGVbeta]
DECIPHERC8orf4 [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisC8orf4 
Mutations
ICGC Data PortalC8orf4 
TCGA Data PortalC8orf4 
Broad Tumor PortalC8orf4
OASIS PortalC8orf4 [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICC8orf4  [overview]  [genome browser]  [tissue]  [distribution]  
Mutations and Diseases : HGMDC8orf4
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD - Leiden Open Variation Database
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
BioMutasearch C8orf4
DgiDB (Drug Gene Interaction Database)C8orf4
DoCM (Curated mutations)C8orf4 (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)C8orf4 (select a term)
intoGenC8orf4
Cancer3DC8orf4(select the gene name)
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM607702   
Orphanet
MedgenC8orf4
Genetic Testing Registry C8orf4
NextProtQ9NR00 [Medical]
TSGene56892
GENETestsC8orf4
Target ValidationC8orf4
Huge Navigator C8orf4 [HugePedia]
snp3D : Map Gene to Disease56892
BioCentury BCIQC8orf4
ClinGenC8orf4
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD56892
Chemical/Pharm GKB GenePA25962
Clinical trialC8orf4
Miscellaneous
canSAR (ICR)C8orf4 (select the gene name)
Probes
Litterature
PubMed25 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineC8orf4
EVEXC8orf4
GoPubMedC8orf4
iHOPC8orf4
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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© Atlas of Genetics and Cytogenetics in Oncology and Haematology
indexed on : Wed Jun 7 12:26:20 CEST 2017

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