CA10 (carbonic anhydrase 10)

2017-10-01  

Identity

HGNC
LOCATION
17q21.33
LOCUSID
ALIAS
CA-RPX,CARPX,HUCEP-15
FUSION GENES

Other Information

Locus ID:

NCBI: 56934
MIM: 604642
HGNC: 1369
Ensembl: ENSG00000154975

Variants:

dbSNP: 56934
ClinVar: 56934
TCGA: ENSG00000154975
COSMIC: CA10

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000154975ENST00000285273Q9NS85
ENSG00000154975ENST00000285273A0A384MTY8
ENSG00000154975ENST00000442502Q9NS85
ENSG00000154975ENST00000442502A0A384MTY8
ENSG00000154975ENST00000451037Q9NS85
ENSG00000154975ENST00000451037A0A384MTY8
ENSG00000154975ENST00000570565Q9NS85
ENSG00000154975ENST00000571371I3NI54
ENSG00000154975ENST00000575097I3L0J7
ENSG00000154975ENST00000575181I3L375

Expression (GTEx)

0
50
100
150
200

Protein levels (Protein atlas)

Not detected
Low
Medium
High

PharmGKB

Entity IDNameTypeEvidenceAssociationPKPDPMIDs
PA443450AsthmaDiseaseClinicalAnnotationassociatedPD24407380
PA449686fluticasone propionateChemicalClinicalAnnotationassociatedPD24407380
PA450546montelukastChemicalClinicalAnnotationassociatedPD24407380

References

Pubmed IDYearTitleCitations
192400612009Coeliac disease-associated risk variants in TNFAIP3 and REL implicate altered NF-kappaB signalling.75
203796142010Personalized smoking cessation: interactions between nicotine dose, dependence and quit-success genotype score.62
265075512015Genome-wide association study identifies African-ancestry specific variants for metabolic syndrome.16
281541402017Carbonic anhydrase-related protein CA10 is an evolutionarily conserved pan-neurexin ligand.16
244073802014Polymorphisms in recent GWA identified asthma genes CA10, SGK493, and CTNNA3 are associated with disease severity and treatment response in childhood asthma.8
99219011998CCG repeats in cDNAs from human brain.5
191722212009Nucleotide variations in genes encoding carbonic anhydrase 8 and 10 associated with femoral bone mineral density in Japanese female with osteoporosis.4
191722212009Nucleotide variations in genes encoding carbonic anhydrase 8 and 10 associated with femoral bone mineral density in Japanese female with osteoporosis.4
285372442017[Transcription factors NF-kB, HIF-1, HIF-2, growth factor VEGF, VEGFR2 and carboanhydrase IX mRNA and protein level in the development of kidney cancer metastasis].4
292916172018Methylation Status of Transcriptional Modulatory Genes Associated with Colorectal Cancer in Northeast China.4

Citation

Dessen P

CA10 (carbonic anhydrase 10)

Atlas Genet Cytogenet Oncol Haematol. 2017-10-01

Online version: http://atlasgeneticsoncology.org/gene/57185/ca10