CA14 (carbonic anhydrase 14)

2014-11-01  

Identity

HGNC
LOCATION
1q21.2
LOCUSID
ALIAS
CAXiV
FUSION GENES

Other Information

Locus ID:

NCBI: 23632
MIM: 604832
HGNC: 1372
Ensembl: ENSG00000118298

Variants:

dbSNP: 23632
ClinVar: 23632
TCGA: ENSG00000118298
COSMIC: CA14

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000118298ENST00000369111Q9ULX7
ENSG00000118298ENST00000369111A8K3J4
ENSG00000118298ENST00000483993U3KQH0
ENSG00000118298ENST00000607082U3KPU6
ENSG00000118298ENST00000647854Q9ULX7
ENSG00000118298ENST00000647854A8K3J4

Expression (GTEx)

0
5
10
15
20
25
30
35
40

Pathways

PathwaySourceExternal ID
Nitrogen metabolismKEGGko00910
Nitrogen metabolismKEGGhsa00910
MetabolismREACTOMER-HSA-1430728
Reversible hydration of carbon dioxideREACTOMER-HSA-1475029

Protein levels (Protein atlas)

Not detected
Low
Medium
High

References

Pubmed IDYearTitleCitations
203796142010Personalized smoking cessation: interactions between nicotine dose, dependence and quit-success genotype score.62
178814262008Familial pure proximal renal tubular acidosis--a clinical and genetic study.12
201700952010Identification of 3,4-Dihydroisoquinoline-2(1H)-sulfonamides as potent carbonic anhydrase inhibitors: synthesis, biological evaluation, and enzyme--ligand X-ray studies.4
243744842014The structural comparison between membrane-associated human carbonic anhydrases provides insights into drug design of selective inhibitors.4

Citation

Dessen P

CA14 (carbonic anhydrase 14)

Atlas Genet Cytogenet Oncol Haematol. 2014-11-01

Online version: http://atlasgeneticsoncology.org/gene/61340/ca14