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CA3 (carbonic anhydrase 3)

Identity

Alias_namescarbonic anhydrase III, muscle specific
carbonic anhydrase III
Alias_symbol (synonym)Car3
CAIII
Other alias
HGNC (Hugo) CA3
LocusID (NCBI) 761
Atlas_Id 61341
Location 8q21.2  [Link to chromosome band 8q21]
Location_base_pair Starts at 85438827 and ends at 85449038 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2016)
CA3 (8q21.2) / MYBL1 (8q13.1)

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


External links

Nomenclature
HGNC (Hugo)CA3   1374
Cards
Entrez_Gene (NCBI)CA3  761  carbonic anhydrase 3
AliasesCAIII; Car3
GeneCards (Weizmann)CA3
Ensembl hg19 (Hinxton)ENSG00000164879 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000164879 [Gene_View]  chr8:85438827-85449038 [Contig_View]  CA3 [Vega]
ICGC DataPortalENSG00000164879
TCGA cBioPortalCA3
AceView (NCBI)CA3
Genatlas (Paris)CA3
WikiGenes761
SOURCE (Princeton)CA3
Genetics Home Reference (NIH)CA3
Genomic and cartography
GoldenPath hg38 (UCSC)CA3  -     chr8:85438827-85449038 +  8q21.2   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)CA3  -     8q21.2   [Description]    (hg19-Feb_2009)
EnsemblCA3 - 8q21.2 [CytoView hg19]  CA3 - 8q21.2 [CytoView hg38]
Mapping of homologs : NCBICA3 [Mapview hg19]  CA3 [Mapview hg38]
OMIM114750   
Gene and transcription
Genbank (Entrez)AK096880 AK300670 AK300677 AK313254 BC004897
RefSeq transcript (Entrez)NM_005181
RefSeq genomic (Entrez)
Consensus coding sequences : CCDS (NCBI)CA3
Cluster EST : UnigeneHs.82129 [ NCBI ]
CGAP (NCI)Hs.82129
Alternative Splicing GalleryENSG00000164879
Gene ExpressionCA3 [ NCBI-GEO ]   CA3 [ EBI - ARRAY_EXPRESS ]   CA3 [ SEEK ]   CA3 [ MEM ]
Gene Expression Viewer (FireBrowse)CA3 [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevisibleExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)761
GTEX Portal (Tissue expression)CA3
Protein : pattern, domain, 3D structure
UniProt/SwissProtP07451   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtP07451  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProP07451
Splice isoforms : SwissVarP07451
Catalytic activity : Enzyme4.2.1.1 [ Enzyme-Expasy ]   4.2.1.14.2.1.1 [ IntEnz-EBI ]   4.2.1.1 [ BRENDA ]   4.2.1.1 [ KEGG ]   
PhosPhoSitePlusP07451
Domaine pattern : Prosite (Expaxy)ALPHA_CA_1 (PS00162)    ALPHA_CA_2 (PS51144)   
Domains : Interpro (EBI)Carbonic_anhydrase_a    Carbonic_anhydrase_a-class    Carbonic_anhydrase_a-class_CS    Carbonic_anhydrase_CA3   
Domain families : Pfam (Sanger)Carb_anhydrase (PF00194)   
Domain families : Pfam (NCBI)pfam00194   
Domain families : Smart (EMBL)Carb_anhydrase (SM01057)  
Conserved Domain (NCBI)CA3
DMDM Disease mutations761
Blocks (Seattle)CA3
PDB (SRS)1Z93    1Z97    2HFW    3UYN    3UYQ   
PDB (PDBSum)1Z93    1Z97    2HFW    3UYN    3UYQ   
PDB (IMB)1Z93    1Z97    2HFW    3UYN    3UYQ   
PDB (RSDB)1Z93    1Z97    2HFW    3UYN    3UYQ   
Structural Biology KnowledgeBase1Z93    1Z97    2HFW    3UYN    3UYQ   
SCOP (Structural Classification of Proteins)1Z93    1Z97    2HFW    3UYN    3UYQ   
CATH (Classification of proteins structures)1Z93    1Z97    2HFW    3UYN    3UYQ   
SuperfamilyP07451
Human Protein AtlasENSG00000164879
Peptide AtlasP07451
HPRD00260
IPIIPI00216983   IPI00909152   IPI01010280   IPI00980797   
Protein Interaction databases
DIP (DOE-UCLA)P07451
IntAct (EBI)P07451
FunCoupENSG00000164879
BioGRIDCA3
STRING (EMBL)CA3
ZODIACCA3
Ontologies - Pathways
QuickGOP07451
Ontology : AmiGOcarbonate dehydratase activity  cytosol  one-carbon metabolic process  response to oxidative stress  zinc ion binding  bicarbonate transport  nickel cation binding  dephosphorylation  phosphatase activity  response to ethanol  
Ontology : EGO-EBIcarbonate dehydratase activity  cytosol  one-carbon metabolic process  response to oxidative stress  zinc ion binding  bicarbonate transport  nickel cation binding  dephosphorylation  phosphatase activity  response to ethanol  
Pathways : KEGGNitrogen metabolism   
NDEx NetworkCA3
Atlas of Cancer Signalling NetworkCA3
Wikipedia pathwaysCA3
Orthology - Evolution
OrthoDB761
GeneTree (enSembl)ENSG00000164879
Phylogenetic Trees/Animal Genes : TreeFamCA3
HOVERGENP07451
HOGENOMP07451
Homologs : HomoloGeneCA3
Homology/Alignments : Family Browser (UCSC)CA3
Gene fusions - Rearrangements
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerCA3 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)CA3
dbVarCA3
ClinVarCA3
1000_GenomesCA3 
Exome Variant ServerCA3
ExAC (Exome Aggregation Consortium)CA3 (select the gene name)
Genetic variants : HAPMAP761
Genomic Variants (DGV)CA3 [DGVbeta]
DECIPHERCA3 [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisCA3 
Mutations
ICGC Data PortalCA3 
TCGA Data PortalCA3 
Broad Tumor PortalCA3
OASIS PortalCA3 [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICCA3  [overview]  [genome browser]  [tissue]  [distribution]  
Mutations and Diseases : HGMDCA3
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD - Leiden Open Variation Database
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
BioMutasearch CA3
DgiDB (Drug Gene Interaction Database)CA3
DoCM (Curated mutations)CA3 (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)CA3 (select a term)
intoGenCA3
Cancer3DCA3(select the gene name)
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM114750   
Orphanet
MedgenCA3
Genetic Testing Registry CA3
NextProtP07451 [Medical]
TSGene761
GENETestsCA3
Target ValidationCA3
Huge Navigator CA3 [HugePedia]
snp3D : Map Gene to Disease761
BioCentury BCIQCA3
ClinGenCA3
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD761
Chemical/Pharm GKB GenePA25990
Clinical trialCA3
Miscellaneous
canSAR (ICR)CA3 (select the gene name)
Probes
Litterature
PubMed46 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineCA3
EVEXCA3
GoPubMedCA3
iHOPCA3
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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indexed on : Wed Jun 7 15:41:49 CEST 2017

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