Atlas of Genetics and Cytogenetics in Oncology and Haematology


Home   Genes   Leukemias   Solid Tumors   Cancer-Prone   Deep Insight   Case Reports   Journals  Portal   Teaching   

X Y 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22 NA

CA6 (carbonic anhydrase 6)

Identity

Alias_namescarbonic anhydrase VI
Other aliasCA-VI
GUSTIN
HGNC (Hugo) CA6
LocusID (NCBI) 765
Atlas_Id 897
Location 1p36.23  [Link to chromosome band 1p36]
Location_base_pair Starts at 8945834 and ends at 8975089 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2016)
SKI (1p36.33) / CA6 (1p36.23)SKI 1p36.33 / CA6 1p36.23

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


External links

Nomenclature
HGNC (Hugo)CA6   1380
Cards
Entrez_Gene (NCBI)CA6  765  carbonic anhydrase 6
AliasesCA-VI; GUSTIN
GeneCards (Weizmann)CA6
Ensembl hg19 (Hinxton)ENSG00000131686 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000131686 [Gene_View]  chr1:8945834-8975089 [Contig_View]  CA6 [Vega]
ICGC DataPortalENSG00000131686
TCGA cBioPortalCA6
AceView (NCBI)CA6
Genatlas (Paris)CA6
WikiGenes765
SOURCE (Princeton)CA6
Genetics Home Reference (NIH)CA6
Genomic and cartography
GoldenPath hg38 (UCSC)CA6  -     chr1:8945834-8975089 +  1p36.23   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)CA6  -     1p36.23   [Description]    (hg19-Feb_2009)
EnsemblCA6 - 1p36.23 [CytoView hg19]  CA6 - 1p36.23 [CytoView hg38]
Mapping of homologs : NCBICA6 [Mapview hg19]  CA6 [Mapview hg38]
OMIM114780   
Gene and transcription
Genbank (Entrez)AB102863 AB103090 AB103091 AK300652 BC034350
RefSeq transcript (Entrez)NM_001215 NM_001270500 NM_001270501 NM_001270502
RefSeq genomic (Entrez)
Consensus coding sequences : CCDS (NCBI)CA6
Cluster EST : UnigeneHs.100322 [ NCBI ]
CGAP (NCI)Hs.100322
Alternative Splicing GalleryENSG00000131686
Gene ExpressionCA6 [ NCBI-GEO ]   CA6 [ EBI - ARRAY_EXPRESS ]   CA6 [ SEEK ]   CA6 [ MEM ]
Gene Expression Viewer (FireBrowse)CA6 [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevisibleExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)765
GTEX Portal (Tissue expression)CA6
Protein : pattern, domain, 3D structure
UniProt/SwissProtP23280   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtP23280  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProP23280
Splice isoforms : SwissVarP23280
Catalytic activity : Enzyme4.2.1.1 [ Enzyme-Expasy ]   4.2.1.14.2.1.1 [ IntEnz-EBI ]   4.2.1.1 [ BRENDA ]   4.2.1.1 [ KEGG ]   
PhosPhoSitePlusP23280
Domaine pattern : Prosite (Expaxy)ALPHA_CA_1 (PS00162)    ALPHA_CA_2 (PS51144)   
Domains : Interpro (EBI)Carbonic_anhydrase_a    Carbonic_anhydrase_a-class    Carbonic_anhydrase_a-class_CS    Carbonic_anhydrase_CA6   
Domain families : Pfam (Sanger)Carb_anhydrase (PF00194)   
Domain families : Pfam (NCBI)pfam00194   
Domain families : Smart (EMBL)Carb_anhydrase (SM01057)  
Conserved Domain (NCBI)CA6
DMDM Disease mutations765
Blocks (Seattle)CA6
PDB (SRS)3FE4   
PDB (PDBSum)3FE4   
PDB (IMB)3FE4   
PDB (RSDB)3FE4   
Structural Biology KnowledgeBase3FE4   
SCOP (Structural Classification of Proteins)3FE4   
CATH (Classification of proteins structures)3FE4   
SuperfamilyP23280
Human Protein AtlasENSG00000131686
Peptide AtlasP23280
HPRD00264
IPIIPI00295105   IPI00554696   IPI00554773   IPI01022662   IPI00166698   
Protein Interaction databases
DIP (DOE-UCLA)P23280
IntAct (EBI)P23280
FunCoupENSG00000131686
BioGRIDCA6
STRING (EMBL)CA6
ZODIACCA6
Ontologies - Pathways
QuickGOP23280
Ontology : AmiGOdetection of chemical stimulus involved in sensory perception of bitter taste  carbonate dehydratase activity  extracellular region  extracellular space  cytosol  one-carbon metabolic process  zinc ion binding  bicarbonate transport  extracellular exosome  
Ontology : EGO-EBIdetection of chemical stimulus involved in sensory perception of bitter taste  carbonate dehydratase activity  extracellular region  extracellular space  cytosol  one-carbon metabolic process  zinc ion binding  bicarbonate transport  extracellular exosome  
Pathways : KEGGNitrogen metabolism   
NDEx NetworkCA6
Atlas of Cancer Signalling NetworkCA6
Wikipedia pathwaysCA6
Orthology - Evolution
OrthoDB765
GeneTree (enSembl)ENSG00000131686
Phylogenetic Trees/Animal Genes : TreeFamCA6
HOVERGENP23280
HOGENOMP23280
Homologs : HomoloGeneCA6
Homology/Alignments : Family Browser (UCSC)CA6
Gene fusions - Rearrangements
Fusion : MitelmanSKI/CA6 [1p36.33/1p36.23]  [t(1;1)(p36;p36)]  
Fusion: TCGASKI 1p36.33 CA6 1p36.23 SKCM
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerCA6 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)CA6
dbVarCA6
ClinVarCA6
1000_GenomesCA6 
Exome Variant ServerCA6
ExAC (Exome Aggregation Consortium)CA6 (select the gene name)
Genetic variants : HAPMAP765
Genomic Variants (DGV)CA6 [DGVbeta]
DECIPHERCA6 [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisCA6 
Mutations
ICGC Data PortalCA6 
TCGA Data PortalCA6 
Broad Tumor PortalCA6
OASIS PortalCA6 [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICCA6  [overview]  [genome browser]  [tissue]  [distribution]  
Mutations and Diseases : HGMDCA6
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD - Leiden Open Variation Database
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
BioMutasearch CA6
DgiDB (Drug Gene Interaction Database)CA6
DoCM (Curated mutations)CA6 (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)CA6 (select a term)
intoGenCA6
Cancer3DCA6(select the gene name)
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM114780   
Orphanet
MedgenCA6
Genetic Testing Registry CA6
NextProtP23280 [Medical]
TSGene765
GENETestsCA6
Target ValidationCA6
Huge Navigator CA6 [HugePedia]
snp3D : Map Gene to Disease765
BioCentury BCIQCA6
ClinGenCA6
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD765
Chemical/Pharm GKB GenePA25995
Clinical trialCA6
Miscellaneous
canSAR (ICR)CA6 (select the gene name)
Probes
Litterature
PubMed39 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineCA6
EVEXCA6
GoPubMedCA6
iHOPCA6
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

Search in all EBI   NCBI

© Atlas of Genetics and Cytogenetics in Oncology and Haematology
indexed on : Mon Sep 25 19:00:09 CEST 2017

Home   Genes   Leukemias   Solid Tumors   Cancer-Prone   Deep Insight   Case Reports   Journals  Portal   Teaching   

For comments and suggestions or contributions, please contact us

jlhuret@AtlasGeneticsOncology.org.