CABLES2 (Cdk5 and Abl enzyme substrate 2)

2014-11-01  

Identity

HGNC
LOCATION
20q13.33
LOCUSID
ALIAS
C20orf150,dJ908M14.2,ik3-2
FUSION GENES

Other Information

Locus ID:

NCBI: 81928
MIM: 618772
HGNC: 16143
Ensembl: ENSG00000149679

Variants:

dbSNP: 81928
ClinVar: 81928
TCGA: ENSG00000149679
COSMIC: CABLES2

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000149679ENST00000279101Q9BTV7
ENSG00000149679ENST00000453274H0Y5H2

Expression (GTEx)

0
10
20
30
40
50
60
70
80
90

Pathways

PathwaySourceExternal ID
HemostasisREACTOMER-HSA-109582
Factors involved in megakaryocyte development and platelet productionREACTOMER-HSA-983231

References

Pubmed IDYearTitleCitations
200566452010Association of mitotic regulation pathway polymorphisms with pancreatic cancer risk and outcome.10
146371682003ik3-2, a relative to ik3-1/Cables, is involved in both p53-mediated and p53-independent apoptotic pathways.5

Citation

Dessen P

CABLES2 (Cdk5 and Abl enzyme substrate 2)

Atlas Genet Cytogenet Oncol Haematol. 2014-11-01

Online version: http://atlasgeneticsoncology.org/gene/61346/cables2