| Nomenclature |
|---|
| HGNC (Hugo) | CACNG2 1406 |
| LRG (Locus Reference Genomic) | LRG_1159 |
| Cards |
|---|
| Entrez_Gene (NCBI) | CACNG2 10369 calcium voltage-gated channel auxiliary subunit gamma 2 |
| Aliases | MRD10 |
| GeneCards (Weizmann) | CACNG2 |
| Ensembl hg19 (Hinxton) | ENSG00000166862 [Gene_View] |
| Ensembl hg38 (Hinxton) | ENSG00000166862 [Gene_View] ENSG00000166862 [Sequence] chr22:36560869-36702858 [Contig_View] CACNG2 [Vega] |
| ICGC DataPortal | ENSG00000166862 |
| TCGA cBioPortal | CACNG2 |
| AceView (NCBI) | CACNG2 |
| Genatlas (Paris) | CACNG2 |
| WikiGenes | 10369 |
| SOURCE (Princeton) | CACNG2 |
| Genetics Home Reference (NIH) | CACNG2 |
| Genomic and cartography |
|---|
| GoldenPath hg38 (UCSC) | CACNG2 - chr22:36560869-36702858 - 22q12.3 [Description] (hg38-Dec_2013) |
| GoldenPath hg19 (UCSC) | CACNG2 - 22q12.3 [Description] (hg19-Feb_2009) |
| Ensembl | CACNG2 - 22q12.3 [CytoView hg19] CACNG2 - 22q12.3 [CytoView hg38] |
| Mapping of homologs : NCBI | CACNG2 [Mapview hg19] CACNG2 [Mapview hg38] |
| OMIM | 602911 614256 |
| Gene and transcription |
|---|
| Genbank (Entrez) | AF096322 AK123431 BC069612 BC112297 BC112299 |
| RefSeq transcript (Entrez) | NM_006078 |
| RefSeq genomic (Entrez) | |
| Consensus coding sequences : CCDS (NCBI) | CACNG2 |
| Cluster EST : Unigene | Hs.146766 [ NCBI ] |
| CGAP (NCI) | Hs.146766 |
| Alternative Splicing Gallery | ENSG00000166862 |
| Gene Expression | CACNG2 [ NCBI-GEO ] CACNG2 [ EBI - ARRAY_EXPRESS ]
CACNG2 [ SEEK ] CACNG2 [ MEM ] |
| Gene Expression Viewer (FireBrowse) | CACNG2 [ Firebrowse - Broad ] |
| SOURCE (Princeton) | Expression in : [Datasets] [Normal Tissue Atlas] [carcinoma Classsification] [NCI60] |
| Genevestigator | Expression in : [tissues] [cell-lines] [cancer] [perturbations] |
| BioGPS (Tissue expression) | 10369 |
| GTEX Portal (Tissue expression) | CACNG2 |
| Human Protein Atlas | ENSG00000166862-CACNG2 [pathology] [cell] [tissue] |
| Protein : pattern, domain, 3D structure |
|---|
| UniProt/SwissProt | Q9Y698 [function] [subcellular_location] [family_and_domains] [pathology_and_biotech] [ptm_processing] [expression] [interaction] |
| NextProt | Q9Y698 [Sequence] [Exons] [Medical] [Publications] |
| With graphics : InterPro | Q9Y698 |
| Splice isoforms : SwissVar | Q9Y698 |
| PhosPhoSitePlus | Q9Y698 |
| Domains : Interpro (EBI) | PMP22/EMP/MP20/Claudin VDCC_g2su VDCC_gsu |
| Domain families : Pfam (Sanger) | PMP22_Claudin (PF00822) |
| Domain families : Pfam (NCBI) | pfam00822 |
| Conserved Domain (NCBI) | CACNG2 |
| DMDM Disease mutations | 10369 |
| Blocks (Seattle) | CACNG2 |
| Superfamily | Q9Y698 |
| Human Protein Atlas [tissue] | ENSG00000166862-CACNG2 [tissue] |
| Peptide Atlas | Q9Y698 |
| HPRD | 04220 |
| IPI | IPI00001962 |
| Protein Interaction databases |
|---|
| DIP (DOE-UCLA) | Q9Y698 |
| IntAct (EBI) | Q9Y698 |
| FunCoup | ENSG00000166862 |
| BioGRID | CACNG2 |
| STRING (EMBL) | CACNG2 |
| ZODIAC | CACNG2 |
| Ontologies - Pathways |
|---|
| QuickGO | Q9Y698 |
| Ontology : AmiGO | voltage-gated calcium channel activity calcium channel activity protein binding plasma membrane voltage-gated calcium channel complex neuromuscular junction development channel regulator activity transmission of nerve impulse cell junction endocytic vesicle membrane AMPA glutamate receptor complex AMPA glutamate receptor complex ionotropic glutamate receptor binding somatodendritic compartment neuron projection membrane depolarization positive regulation of synaptic transmission, glutamatergic membrane hyperpolarization postsynaptic density membrane postsynaptic density membrane neurotransmitter receptor transport, postsynaptic endosome to lysosome neurotransmitter receptor transport, postsynaptic endosome to lysosome postsynaptic neurotransmitter receptor diffusion trapping postsynaptic neurotransmitter receptor diffusion trapping neurotransmitter receptor internalization neurotransmitter receptor internalization regulation of AMPA receptor activity regulation of AMPA receptor activity |
| Ontology : EGO-EBI | voltage-gated calcium channel activity calcium channel activity protein binding plasma membrane voltage-gated calcium channel complex neuromuscular junction development channel regulator activity transmission of nerve impulse cell junction endocytic vesicle membrane AMPA glutamate receptor complex AMPA glutamate receptor complex ionotropic glutamate receptor binding somatodendritic compartment neuron projection membrane depolarization positive regulation of synaptic transmission, glutamatergic membrane hyperpolarization postsynaptic density membrane postsynaptic density membrane neurotransmitter receptor transport, postsynaptic endosome to lysosome neurotransmitter receptor transport, postsynaptic endosome to lysosome postsynaptic neurotransmitter receptor diffusion trapping postsynaptic neurotransmitter receptor diffusion trapping neurotransmitter receptor internalization neurotransmitter receptor internalization regulation of AMPA receptor activity regulation of AMPA receptor activity |
| Pathways : KEGG | MAPK signaling pathway Cardiac muscle contraction Adrenergic signaling in cardiomyocytes Hypertrophic cardiomyopathy (HCM) Arrhythmogenic right ventricular cardiomyopathy (ARVC) Dilated cardiomyopathy |
| NDEx Network | CACNG2 |
| Atlas of Cancer Signalling Network | CACNG2 |
| Wikipedia pathways | CACNG2 |
| Orthology - Evolution |
|---|
| OrthoDB | 10369 |
| GeneTree (enSembl) | ENSG00000166862 |
| Phylogenetic Trees/Animal Genes : TreeFam | CACNG2 |
| HOVERGEN | Q9Y698 |
| HOGENOM | Q9Y698 |
| Homologs : HomoloGene | CACNG2 |
| Homology/Alignments : Family Browser (UCSC) | CACNG2 |
| Gene fusions - Rearrangements |
|---|
| Fusion : Quiver | CACNG2 |
| Polymorphisms : SNP and Copy number variants |
|---|
| NCBI Variation Viewer | CACNG2 [hg38] |
| dbSNP Single Nucleotide Polymorphism (NCBI) | CACNG2 |
| dbVar | CACNG2 |
| ClinVar | CACNG2 |
| 1000_Genomes | CACNG2 |
| Exome Variant Server | CACNG2 |
| ExAC (Exome Aggregation Consortium) | ENSG00000166862 |
| GNOMAD Browser | ENSG00000166862 |
| Varsome Browser | CACNG2 |
| Genetic variants : HAPMAP | 10369 |
| Genomic Variants (DGV) | CACNG2 [DGVbeta] |
| DECIPHER | CACNG2 [patients] [syndromes] [variants] [genes] |
| CONAN: Copy Number Analysis | CACNG2 |
| Mutations |
|---|
| ICGC Data Portal | CACNG2 |
| TCGA Data Portal | CACNG2 |
| Broad Tumor Portal | CACNG2 |
| OASIS Portal | CACNG2 [ Somatic mutations - Copy number] |
| Somatic Mutations in Cancer : COSMIC | CACNG2 [overview] [genome browser] [tissue] [distribution] |
| Mutations and Diseases : HGMD | CACNG2 |
| LOVD (Leiden Open Variation Database) | Whole genome datasets |
| LOVD (Leiden Open Variation Database) | LOVD 3.0 shared installation |
| BioMuta | search CACNG2 |
| DgiDB (Drug Gene Interaction Database) | CACNG2 |
| DoCM (Curated mutations) | CACNG2 (select the gene name) |
| CIViC (Clinical Interpretations of Variants in Cancer) | CACNG2 (select a term) |
| intoGen | CACNG2 |
| Cancer3D | CACNG2(select the gene name) |
| Impact of mutations | [PolyPhen2] [Provean] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser] |
| Diseases |
|---|
| OMIM | 602911 614256 |
| Orphanet | 18028 |
| DisGeNET | CACNG2 |
| Medgen | CACNG2 |
| Genetic Testing Registry | CACNG2
|
| NextProt | Q9Y698 [Medical] |
| TSGene | 10369 |
| GENETests | CACNG2 |
| Target Validation | CACNG2 |
| Huge Navigator |
CACNG2 [HugePedia] |
| snp3D : Map Gene to Disease | 10369 |
| BioCentury BCIQ | CACNG2 |
| ClinGen | CACNG2 |
| Clinical trials, drugs, therapy |
|---|
| Chemical/Protein Interactions : CTD | 10369 |
| Chemical/Pharm GKB Gene | PA26016 |
| Clinical trial | CACNG2 |
| Miscellaneous |
|---|
| canSAR (ICR) | CACNG2 (select the gene name) |
| Probes |
|---|
| Litterature |
|---|
| PubMed | 41 Pubmed reference(s) in Entrez |
| GeneRIFs | Gene References Into Functions (Entrez) |
| CoreMine | CACNG2 |
| EVEX | CACNG2 |
| GoPubMed | CACNG2 |
| iHOP | CACNG2 |
