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CACNG4 (calcium voltage-gated channel auxiliary subunit gamma 4)

Identity

Alias (NCBI)-
HGNC (Hugo) CACNG4
HGNC Alias symbMGC11138
MGC24983
HGNC Previous namecalcium channel, voltage-dependent, gamma subunit 4
LocusID (NCBI) 27092
Atlas_Id 57574
Location 17q24.2  [Link to chromosome band 17q24]
Location_base_pair Starts at 66964707 and ends at 67033396 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2017)
Data from Atlas, Mitelman, Cosmic Fusion, Fusion Cancer, TCGA fusion databases with official HUGO symbols (see references in chromosomal bands)
CACNG4 (17q24.2) / C17orf51 (17p11.2)CACNG4 (17q24.2) / VMP1 (17q23.1)HELZ (17q24.2) / CACNG4 (17q24.2)
IQCB1 (3q13.33) / CACNG4 (17q24.2)

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 



External links

 

Nomenclature
HGNC (Hugo)CACNG4   1408
Cards
Entrez_Gene (NCBI)CACNG4    calcium voltage-gated channel auxiliary subunit gamma 4
Aliases
GeneCards (Weizmann)CACNG4
Ensembl hg19 (Hinxton)ENSG00000075461 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000075461 [Gene_View]  ENSG00000075461 [Sequence]  chr17:66964707-67033396 [Contig_View]  CACNG4 [Vega]
ICGC DataPortalENSG00000075461
TCGA cBioPortalCACNG4
AceView (NCBI)CACNG4
Genatlas (Paris)CACNG4
SOURCE (Princeton)CACNG4
Genetics Home Reference (NIH)CACNG4
Genomic and cartography
GoldenPath hg38 (UCSC)CACNG4  -     chr17:66964707-67033396 +  17q24.2   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)CACNG4  -     17q24.2   [Description]    (hg19-Feb_2009)
GoldenPathCACNG4 - 17q24.2 [CytoView hg19]  CACNG4 - 17q24.2 [CytoView hg38]
ImmunoBaseENSG00000075461
Genome Data Viewer NCBICACNG4 [Mapview hg19]  
OMIM606404   
Gene and transcription
Genbank (Entrez)AF162692 AK055232 AK315149 AL526464 AL713655
RefSeq transcript (Entrez)NM_014405
Consensus coding sequences : CCDS (NCBI)CACNG4
Gene ExpressionCACNG4 [ NCBI-GEO ]   CACNG4 [ EBI - ARRAY_EXPRESS ]   CACNG4 [ SEEK ]   CACNG4 [ MEM ]
Gene Expression Viewer (FireBrowse)CACNG4 [ Firebrowse - Broad ]
GenevisibleExpression of CACNG4 in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)27092
GTEX Portal (Tissue expression)CACNG4
Human Protein AtlasENSG00000075461-CACNG4 [pathology]   [cell]   [tissue]
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ9UBN1   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtQ9UBN1  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProQ9UBN1
PhosPhoSitePlusQ9UBN1
Domains : Interpro (EBI)PMP22/EMP/MP20/Claudin    VDCC_g4su    VDCC_gsu   
Domain families : Pfam (Sanger)PMP22_Claudin (PF00822)   
Domain families : Pfam (NCBI)pfam00822   
Conserved Domain (NCBI)CACNG4
SuperfamilyQ9UBN1
AlphaFold pdb e-kbQ9UBN1   
Human Protein Atlas [tissue]ENSG00000075461-CACNG4 [tissue]
Protein Interaction databases
DIP (DOE-UCLA)Q9UBN1
IntAct (EBI)Q9UBN1
BioGRIDCACNG4
STRING (EMBL)CACNG4
ZODIACCACNG4
Ontologies - Pathways
QuickGOQ9UBN1
Ontology : AmiGOvoltage-gated calcium channel activity  calcium channel regulator activity  plasma membrane  integral component of plasma membrane  cell surface  channel regulator activity  transmission of nerve impulse  endocytic vesicle membrane  AMPA glutamate receptor complex  AMPA glutamate receptor complex  ionotropic glutamate receptor binding  somatodendritic compartment  response to cocaine  cell body  membrane depolarization  positive regulation of synaptic transmission, glutamatergic  cardiac conduction  calcium ion transmembrane transport  postsynaptic density membrane  neurotransmitter receptor transport, postsynaptic endosome to lysosome  regulation of postsynaptic neurotransmitter receptor activity  postsynaptic neurotransmitter receptor diffusion trapping  glutamatergic synapse  integral component of postsynaptic density membrane  neurotransmitter receptor internalization  L-type voltage-gated calcium channel complex  regulation of AMPA receptor activity  regulation of AMPA receptor activity  positive regulation of AMPA receptor activity  
Ontology : EGO-EBIvoltage-gated calcium channel activity  calcium channel regulator activity  plasma membrane  integral component of plasma membrane  cell surface  channel regulator activity  transmission of nerve impulse  endocytic vesicle membrane  AMPA glutamate receptor complex  AMPA glutamate receptor complex  ionotropic glutamate receptor binding  somatodendritic compartment  response to cocaine  cell body  membrane depolarization  positive regulation of synaptic transmission, glutamatergic  cardiac conduction  calcium ion transmembrane transport  postsynaptic density membrane  neurotransmitter receptor transport, postsynaptic endosome to lysosome  regulation of postsynaptic neurotransmitter receptor activity  postsynaptic neurotransmitter receptor diffusion trapping  glutamatergic synapse  integral component of postsynaptic density membrane  neurotransmitter receptor internalization  L-type voltage-gated calcium channel complex  regulation of AMPA receptor activity  regulation of AMPA receptor activity  positive regulation of AMPA receptor activity  
Pathways : KEGGMAPK signaling pathway    Cardiac muscle contraction    Adrenergic signaling in cardiomyocytes    Hypertrophic cardiomyopathy (HCM)    Arrhythmogenic right ventricular cardiomyopathy (ARVC)    Dilated cardiomyopathy   
NDEx NetworkCACNG4
Atlas of Cancer Signalling NetworkCACNG4
Wikipedia pathwaysCACNG4
Orthology - Evolution
OrthoDB27092
GeneTree (enSembl)ENSG00000075461
Phylogenetic Trees/Animal Genes : TreeFamCACNG4
Homologs : HomoloGeneCACNG4
Homology/Alignments : Family Browser (UCSC)CACNG4
Gene fusions - Rearrangements
Fusion : QuiverCACNG4
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerCACNG4 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)CACNG4
dbVarCACNG4
ClinVarCACNG4
MonarchCACNG4
1000_GenomesCACNG4 
Exome Variant ServerCACNG4
GNOMAD BrowserENSG00000075461
Varsome BrowserCACNG4
ACMGCACNG4 variants
VarityQ9UBN1
Genomic Variants (DGV)CACNG4 [DGVbeta]
DECIPHERCACNG4 [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisCACNG4 
Mutations
ICGC Data PortalCACNG4 
TCGA Data PortalCACNG4 
Broad Tumor PortalCACNG4
OASIS PortalCACNG4 [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICCACNG4  [overview]  [genome browser]  [tissue]  [distribution]  
Somatic Mutations in Cancer : COSMIC3DCACNG4
Mutations and Diseases : HGMDCACNG4
LOVD (Leiden Open Variation Database)[gene] [transcripts] [variants]
BioMutaCACNG4
DgiDB (Drug Gene Interaction Database)CACNG4
DoCM (Curated mutations)CACNG4
CIViC (Clinical Interpretations of Variants in Cancer)CACNG4
Cancer3DCACNG4
Impact of mutations[PolyPhen2] [Provean] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM606404   
Orphanet
DisGeNETCACNG4
MedgenCACNG4
Genetic Testing Registry CACNG4
NextProtQ9UBN1 [Medical]
GENETestsCACNG4
Target ValidationCACNG4
Huge Navigator CACNG4 [HugePedia]
ClinGenCACNG4
Clinical trials, drugs, therapy
MyCancerGenomeCACNG4
Protein Interactions : CTDCACNG4
Pharm GKB GenePA26018
PharosQ9UBN1
Clinical trialCACNG4
Miscellaneous
canSAR (ICR)CACNG4
HarmonizomeCACNG4
DataMed IndexCACNG4
Probes
Litterature
PubMed19 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
EVEXCACNG4
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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© Atlas of Genetics and Cytogenetics in Oncology and Haematology
indexed on : Mon Oct 4 15:02:00 CEST 2021

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