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CACTIN (cactin, spliceosome C complex subunit)

Identity

Alias_namesC19orf29
chromosome 19 open reading frame 29
Alias_symbol (synonym)NY-REN-24
fSAPc
cactin
Other alias
HGNC (Hugo) CACTIN
LocusID (NCBI) 58509
Atlas_Id 52793
Location 19p13.3  [Link to chromosome band 19p13]
Location_base_pair Starts at 3610629 and ends at 3626815 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2016)
LPCAT2 (16q12.2) / CACTIN (19p13.3)

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


External links

Nomenclature
HGNC (Hugo)CACTIN   29938
Cards
Entrez_Gene (NCBI)CACTIN  58509  cactin, spliceosome C complex subunit
AliasesC19orf29; NY-REN-24; fSAPc
GeneCards (Weizmann)CACTIN
Ensembl hg19 (Hinxton)ENSG00000105298 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000105298 [Gene_View]  chr19:3610629-3626815 [Contig_View]  CACTIN [Vega]
ICGC DataPortalENSG00000105298
TCGA cBioPortalCACTIN
AceView (NCBI)CACTIN
Genatlas (Paris)CACTIN
WikiGenes58509
SOURCE (Princeton)CACTIN
Genetics Home Reference (NIH)CACTIN
Genomic and cartography
GoldenPath hg38 (UCSC)CACTIN  -     chr19:3610629-3626815 -  19p13.3   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)CACTIN  -     19p13.3   [Description]    (hg19-Feb_2009)
EnsemblCACTIN - 19p13.3 [CytoView hg19]  CACTIN - 19p13.3 [CytoView hg38]
Mapping of homologs : NCBICACTIN [Mapview hg19]  CACTIN [Mapview hg38]
Gene and transcription
Genbank (Entrez)AF052087 AF155102 AK299963 AW027691 AY917150
RefSeq transcript (Entrez)NM_001080543 NM_021231
RefSeq genomic (Entrez)
Consensus coding sequences : CCDS (NCBI)CACTIN
Cluster EST : UnigeneHs.128425 [ NCBI ]
CGAP (NCI)Hs.128425
Alternative Splicing GalleryENSG00000105298
Gene ExpressionCACTIN [ NCBI-GEO ]   CACTIN [ EBI - ARRAY_EXPRESS ]   CACTIN [ SEEK ]   CACTIN [ MEM ]
Gene Expression Viewer (FireBrowse)CACTIN [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevisibleExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)58509
GTEX Portal (Tissue expression)CACTIN
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ8WUQ7   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtQ8WUQ7  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProQ8WUQ7
Splice isoforms : SwissVarQ8WUQ7
PhosPhoSitePlusQ8WUQ7
Domains : Interpro (EBI)Cactin_C    Cactin_central   
Domain families : Pfam (Sanger)Cactin_mid (PF10312)    CactinC_cactus (PF09732)   
Domain families : Pfam (NCBI)pfam10312    pfam09732   
Conserved Domain (NCBI)CACTIN
DMDM Disease mutations58509
Blocks (Seattle)CACTIN
SuperfamilyQ8WUQ7
Human Protein AtlasENSG00000105298
Peptide AtlasQ8WUQ7
IPIIPI00736681   IPI00022225   IPI00940980   
Protein Interaction databases
DIP (DOE-UCLA)Q8WUQ7
IntAct (EBI)Q8WUQ7
FunCoupENSG00000105298
BioGRIDCACTIN
STRING (EMBL)CACTIN
ZODIACCACTIN
Ontologies - Pathways
QuickGOQ8WUQ7
Ontology : AmiGOmRNA splicing, via spliceosome  negative regulation of protein phosphorylation  RNA binding  protein binding  nucleus  nucleoplasm  cytosol  multicellular organism development  nuclear speck  negative regulation of lipopolysaccharide-mediated signaling pathway  negative regulation of NF-kappaB transcription factor activity  negative regulation of interferon-beta production  negative regulation of interleukin-8 production  negative regulation of tumor necrosis factor production  negative regulation of toll-like receptor signaling pathway  innate immune response  negative regulation of type I interferon-mediated signaling pathway  extracellular exosome  catalytic step 2 spliceosome  cellular response to lipopolysaccharide  cellular response to interleukin-1  cellular response to tumor necrosis factor  
Ontology : EGO-EBImRNA splicing, via spliceosome  negative regulation of protein phosphorylation  RNA binding  protein binding  nucleus  nucleoplasm  cytosol  multicellular organism development  nuclear speck  negative regulation of lipopolysaccharide-mediated signaling pathway  negative regulation of NF-kappaB transcription factor activity  negative regulation of interferon-beta production  negative regulation of interleukin-8 production  negative regulation of tumor necrosis factor production  negative regulation of toll-like receptor signaling pathway  innate immune response  negative regulation of type I interferon-mediated signaling pathway  extracellular exosome  catalytic step 2 spliceosome  cellular response to lipopolysaccharide  cellular response to interleukin-1  cellular response to tumor necrosis factor  
NDEx NetworkCACTIN
Atlas of Cancer Signalling NetworkCACTIN
Wikipedia pathwaysCACTIN
Orthology - Evolution
OrthoDB58509
GeneTree (enSembl)ENSG00000105298
Phylogenetic Trees/Animal Genes : TreeFamCACTIN
HOVERGENQ8WUQ7
HOGENOMQ8WUQ7
Homologs : HomoloGeneCACTIN
Homology/Alignments : Family Browser (UCSC)CACTIN
Gene fusions - Rearrangements
Fusion : MitelmanLPCAT2/CACTIN [16q12.2/19p13.3]  [t(16;19)(q12;p13)]  
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerCACTIN [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)CACTIN
dbVarCACTIN
ClinVarCACTIN
1000_GenomesCACTIN 
Exome Variant ServerCACTIN
ExAC (Exome Aggregation Consortium)CACTIN (select the gene name)
Genetic variants : HAPMAP58509
Genomic Variants (DGV)CACTIN [DGVbeta]
DECIPHERCACTIN [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisCACTIN 
Mutations
ICGC Data PortalCACTIN 
TCGA Data PortalCACTIN 
Broad Tumor PortalCACTIN
OASIS PortalCACTIN [ Somatic mutations - Copy number]
Mutations and Diseases : HGMDCACTIN
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD - Leiden Open Variation Database
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
BioMutasearch CACTIN
DgiDB (Drug Gene Interaction Database)CACTIN
DoCM (Curated mutations)CACTIN (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)CACTIN (select a term)
intoGenCACTIN
Cancer3DCACTIN(select the gene name)
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM
Orphanet
MedgenCACTIN
Genetic Testing Registry CACTIN
NextProtQ8WUQ7 [Medical]
TSGene58509
GENETestsCACTIN
Huge Navigator CACTIN [HugePedia]
snp3D : Map Gene to Disease58509
BioCentury BCIQCACTIN
ClinGenCACTIN
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD58509
Chemical/Pharm GKB GenePA134932683
Clinical trialCACTIN
Miscellaneous
canSAR (ICR)CACTIN (select the gene name)
Probes
Litterature
PubMed26 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineCACTIN
EVEXCACTIN
GoPubMedCACTIN
iHOPCACTIN
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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indexed on : Fri May 19 12:08:39 CEST 2017

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