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CACUL1 (CDK2 associated cullin domain 1)

Identity

Alias (NCBI)C10orf46
CAC1
HGNC (Hugo) CACUL1
HGNC Alias symbFLJ40409
MGC33215
CAC1
HGNC Alias nameCdk-Associated Cullin1
HGNC Previous nameC10orf46
HGNC Previous namechromosome 10 open reading frame 46
 CDK2-associated, cullin domain 1
LocusID (NCBI) 143384
Atlas_Id 53216
Location 10q26.11  [Link to chromosome band 10q26]
Location_base_pair Starts at 118676411 and ends at 118754970 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2017)
Data from Atlas, Mitelman, Cosmic Fusion, Fusion Cancer, TCGA fusion databases with official HUGO symbols (see references in chromosomal bands)
CACUL1 (10q26.11) / EIF3A (10q26.11)

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 



External links

 

Nomenclature
HGNC (Hugo)CACUL1   23727
Cards
Entrez_Gene (NCBI)CACUL1    CDK2 associated cullin domain 1
AliasesC10orf46; CAC1
GeneCards (Weizmann)CACUL1
Ensembl hg19 (Hinxton)ENSG00000151893 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000151893 [Gene_View]  ENSG00000151893 [Sequence]  chr10:118676411-118754970 [Contig_View]  CACUL1 [Vega]
ICGC DataPortalENSG00000151893
TCGA cBioPortalCACUL1
AceView (NCBI)CACUL1
Genatlas (Paris)CACUL1
SOURCE (Princeton)CACUL1
Genetics Home Reference (NIH)CACUL1
Genomic and cartography
GoldenPath hg38 (UCSC)CACUL1  -     chr10:118676411-118754970 -  10q26.11   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)CACUL1  -     10q26.11   [Description]    (hg19-Feb_2009)
GoldenPathCACUL1 - 10q26.11 [CytoView hg19]  CACUL1 - 10q26.11 [CytoView hg38]
ImmunoBaseENSG00000151893
Genome Data Viewer NCBICACUL1 [Mapview hg19]  
OMIM618764   
Gene and transcription
Genbank (Entrez)AJ544771 AK026985 AK057742 AK097728 AK131008
RefSeq transcript (Entrez)NM_153810
Consensus coding sequences : CCDS (NCBI)CACUL1
Gene ExpressionCACUL1 [ NCBI-GEO ]   CACUL1 [ EBI - ARRAY_EXPRESS ]   CACUL1 [ SEEK ]   CACUL1 [ MEM ]
Gene Expression Viewer (FireBrowse)CACUL1 [ Firebrowse - Broad ]
GenevisibleExpression of CACUL1 in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)143384
GTEX Portal (Tissue expression)CACUL1
Human Protein AtlasENSG00000151893-CACUL1 [pathology]   [cell]   [tissue]
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ86Y37   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtQ86Y37  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProQ86Y37
PhosPhoSitePlusQ86Y37
Domains : Interpro (EBI)CACUL1    Cullin_N    Cullin_repeat-like_dom_sf   
Domain families : Pfam (Sanger)Cullin (PF00888)   
Domain families : Pfam (NCBI)pfam00888   
Conserved Domain (NCBI)CACUL1
SuperfamilyQ86Y37
AlphaFold pdb e-kbQ86Y37   
Human Protein Atlas [tissue]ENSG00000151893-CACUL1 [tissue]
HPRD12576
Protein Interaction databases
DIP (DOE-UCLA)Q86Y37
IntAct (EBI)Q86Y37
BioGRIDCACUL1
STRING (EMBL)CACUL1
ZODIACCACUL1
Ontologies - Pathways
QuickGOQ86Y37
Ontology : AmiGOG1/S transition of mitotic cell cycle  protein binding  ubiquitin-dependent protein catabolic process  positive regulation of cell population proliferation  protein kinase binding  ubiquitin protein ligase binding  positive regulation of protein kinase activity  
Ontology : EGO-EBIG1/S transition of mitotic cell cycle  protein binding  ubiquitin-dependent protein catabolic process  positive regulation of cell population proliferation  protein kinase binding  ubiquitin protein ligase binding  positive regulation of protein kinase activity  
NDEx NetworkCACUL1
Atlas of Cancer Signalling NetworkCACUL1
Wikipedia pathwaysCACUL1
Orthology - Evolution
OrthoDB143384
GeneTree (enSembl)ENSG00000151893
Phylogenetic Trees/Animal Genes : TreeFamCACUL1
Homologs : HomoloGeneCACUL1
Homology/Alignments : Family Browser (UCSC)CACUL1
Gene fusions - Rearrangements
Fusion : MitelmanCACUL1/EIF3A [10q26.11/10q26.11]  
Fusion : QuiverCACUL1
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerCACUL1 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)CACUL1
dbVarCACUL1
ClinVarCACUL1
MonarchCACUL1
1000_GenomesCACUL1 
Exome Variant ServerCACUL1
GNOMAD BrowserENSG00000151893
Varsome BrowserCACUL1
ACMGCACUL1 variants
VarityQ86Y37
Genomic Variants (DGV)CACUL1 [DGVbeta]
DECIPHERCACUL1 [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisCACUL1 
Mutations
ICGC Data PortalCACUL1 
TCGA Data PortalCACUL1 
Broad Tumor PortalCACUL1
OASIS PortalCACUL1 [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICCACUL1  [overview]  [genome browser]  [tissue]  [distribution]  
Somatic Mutations in Cancer : COSMIC3DCACUL1
Mutations and Diseases : HGMDCACUL1
LOVD (Leiden Open Variation Database)[gene] [transcripts] [variants]
BioMutaCACUL1
DgiDB (Drug Gene Interaction Database)CACUL1
DoCM (Curated mutations)CACUL1
CIViC (Clinical Interpretations of Variants in Cancer)CACUL1
Cancer3DCACUL1
Impact of mutations[PolyPhen2] [Provean] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM618764   
Orphanet
DisGeNETCACUL1
MedgenCACUL1
Genetic Testing Registry CACUL1
NextProtQ86Y37 [Medical]
GENETestsCACUL1
Target ValidationCACUL1
Huge Navigator CACUL1 [HugePedia]
ClinGenCACUL1
Clinical trials, drugs, therapy
MyCancerGenomeCACUL1
Protein Interactions : CTDCACUL1
Pharm GKB GenePA134869023
PharosQ86Y37
Clinical trialCACUL1
Miscellaneous
canSAR (ICR)CACUL1
HarmonizomeCACUL1
DataMed IndexCACUL1
Probes
Litterature
PubMed21 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
EVEXCACUL1
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

Search in all EBI   NCBI

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indexed on : Mon Oct 4 15:02:01 CEST 2021

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