Identity
HGNC
LOCATION
10q26.11
LOCUSID
ALIAS
C10orf46,CAC1
FUSION GENES
Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, contribute in submission tool
Other Information
Locus ID:
NCBI: 143384
MIM: 618764
HGNC: 23727
Ensembl: ENSG00000151893
Variants:
dbSNP: 143384
ClinVar: 143384
TCGA: ENSG00000151893
COSMIC: CACUL1
RNA/Proteins
| Gene ID | Transcript ID | Uniprot |
|---|---|---|
| ENSG00000151893 | ENST00000369151 | Q86Y37 |
| ENSG00000151893 | ENST00000493518 | Q86Y37 |
Expression (GTEx)
References
| Pubmed ID | Year | Title | Citations |
|---|---|---|---|
| 36898988 | 2023 | The Skp1-Cullin1-FBXO1 complex is a pleiotropic regulator required for the formation of gametes and motile forms in Plasmodium berghei. | 8 |
| 36898988 | 2023 | The Skp1-Cullin1-FBXO1 complex is a pleiotropic regulator required for the formation of gametes and motile forms in Plasmodium berghei. | 8 |
| 34080964 | 2021 | CDK-associated Cullin 1 Promotes Cell Proliferation and Inhibits Cell Apoptosis in Human Glioblastoma. | 0 |
| 34080964 | 2021 | CDK-associated Cullin 1 Promotes Cell Proliferation and Inhibits Cell Apoptosis in Human Glioblastoma. | 0 |
| 31504073 | 2019 | CAC1 knockdown reverses drug resistance through the downregulation of P-gp and MRP-1 expression in colorectal cancer. | 12 |
| 31504073 | 2019 | CAC1 knockdown reverses drug resistance through the downregulation of P-gp and MRP-1 expression in colorectal cancer. | 12 |
| 27889610 | 2017 | CACUL1/CAC1 attenuates p53 activity through PML post-translational modification. | 5 |
| 27889610 | 2017 | CACUL1/CAC1 attenuates p53 activity through PML post-translational modification. | 5 |
| 27085459 | 2016 | CACUL1 functions as a negative regulator of androgen receptor in prostate cancer cells. | 3 |
| 27085459 | 2016 | CACUL1 functions as a negative regulator of androgen receptor in prostate cancer cells. | 3 |
| 26314198 | 2015 | miR-106a* inhibits the proliferation of esophageal carcinoma cells by targeting CDK2-associated Cullin 1 (CACUL1). | 2 |
| 26314198 | 2015 | miR-106a* inhibits the proliferation of esophageal carcinoma cells by targeting CDK2-associated Cullin 1 (CACUL1). | 2 |
| 23178685 | 2013 | Negative regulation of ERα by a novel protein CAC1 through association with histone demethylase LSD1. | 11 |
| 23311997 | 2013 | CDK-associated Cullin 1 can promote cell proliferation and inhibit cisplatin-induced apoptosis in the AGS gastric cancer cell line. | 9 |
| 23806693 | 2013 | CDK-associated Cullin 1 promotes cell proliferation with activation of ERK1/2 in human lung cancer A549 cells. | 9 |
Citation
Dessen P
CACUL1 (CDK2 associated cullin domain 1)
Atlas Genet Cytogenet Oncol Haematol. 2013-03-01
Online version: http://atlasgeneticsoncology.org/gene/53216/cacul1
