Atlas of Genetics and Cytogenetics in Oncology and Haematology


Home   Genes   Leukemias   Solid Tumors   Cancer-Prone   Deep Insight   Case Reports   Journals  Portal   Teaching   

X Y 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22 NA

CADM2 (cell adhesion molecule 2)

Identity

Alias_namesIGSF4D
immunoglobulin superfamily
Alias_symbol (synonym)NECL3
Necl-3
SynCAM2
Other aliasSynCAM 2
synCAM2
HGNC (Hugo) CADM2
LocusID (NCBI) 253559
Atlas_Id 52479
Location 3p12.1  [Link to chromosome band 3p12]
Location_base_pair Starts at 84958982 and ends at 86074429 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2016)
CADM2 (3p12.1) / CADM2 (3p12.1)CADM2 (3p12.1) / FARP1 (13q32.2)CADM2 (3p12.1) / FHIT (3p14.2)
CADM2 (3p12.1) / FTX (Xq13.2)CADM2 (3p12.1) / PPP1CC (12q24.11)CPNE8 (12q12) / CADM2 (3p12.1)
DAB1 (1p32.2) / CADM2 (3p12.1)HDLBP (2q37.3) / CADM2 (3p12.1)PTPRN2 (7q36.3) / CADM2 (3p12.1)
ROBO2 (3p12.3) / CADM2 (3p12.1)SLN (11q22.3) / CADM2 (3p12.1)TEFM (17q11.2) / CADM2 (3p12.1)
TFEB (6p21.1) / CADM2 (3p12.1)C17orf42 CADM2 3p12.1CADM2 3p12.1 / FHIT 3p14.2
CPNE8 12q12 / CADM2 3p12.1HDLBP 2q37.3 / CADM2 3p12.1

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


External links

Nomenclature
HGNC (Hugo)CADM2   29849
Cards
Entrez_Gene (NCBI)CADM2  253559  cell adhesion molecule 2
AliasesIGSF4D; NECL3; Necl-3; SynCAM; 
synCAM2
GeneCards (Weizmann)CADM2
Ensembl hg19 (Hinxton)ENSG00000175161 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000175161 [Gene_View]  chr3:84958982-86074429 [Contig_View]  CADM2 [Vega]
ICGC DataPortalENSG00000175161
TCGA cBioPortalCADM2
AceView (NCBI)CADM2
Genatlas (Paris)CADM2
WikiGenes253559
SOURCE (Princeton)CADM2
Genetics Home Reference (NIH)CADM2
Genomic and cartography
GoldenPath hg38 (UCSC)CADM2  -     chr3:84958982-86074429 +  3p12.1   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)CADM2  -     3p12.1   [Description]    (hg19-Feb_2009)
EnsemblCADM2 - 3p12.1 [CytoView hg19]  CADM2 - 3p12.1 [CytoView hg38]
Mapping of homologs : NCBICADM2 [Mapview hg19]  CADM2 [Mapview hg38]
OMIM609938   
Gene and transcription
Genbank (Entrez)AB646739 AB646740 AB646741 AB646742 AB646743
RefSeq transcript (Entrez)NM_001167674 NM_001167675 NM_001256502 NM_001256503 NM_001256504 NM_001256505 NM_153184
RefSeq genomic (Entrez)
Consensus coding sequences : CCDS (NCBI)CADM2
Cluster EST : UnigeneHs.164578 [ NCBI ]
CGAP (NCI)Hs.164578
Alternative Splicing GalleryENSG00000175161
Gene ExpressionCADM2 [ NCBI-GEO ]   CADM2 [ EBI - ARRAY_EXPRESS ]   CADM2 [ SEEK ]   CADM2 [ MEM ]
Gene Expression Viewer (FireBrowse)CADM2 [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevisibleExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)253559
GTEX Portal (Tissue expression)CADM2
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ8N3J6   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtQ8N3J6  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProQ8N3J6
Splice isoforms : SwissVarQ8N3J6
PhosPhoSitePlusQ8N3J6
Domaine pattern : Prosite (Expaxy)IG_LIKE (PS50835)   
Domains : Interpro (EBI)CD80_C2-set    Ig-like_dom    Ig-like_fold    Ig_sub    Ig_sub2    Ig_V-set    Neurexin-like   
Domain families : Pfam (Sanger)C2-set_2 (PF08205)    V-set (PF07686)   
Domain families : Pfam (NCBI)pfam08205    pfam07686   
Domain families : Smart (EMBL)4.1m (SM00294)  IG (SM00409)  IGc2 (SM00408)  
Conserved Domain (NCBI)CADM2
DMDM Disease mutations253559
Blocks (Seattle)CADM2
SuperfamilyQ8N3J6
Human Protein AtlasENSG00000175161
Peptide AtlasQ8N3J6
HPRD11046
IPIIPI00413016   IPI00470388   IPI00293836   
Protein Interaction databases
DIP (DOE-UCLA)Q8N3J6
IntAct (EBI)Q8N3J6
FunCoupENSG00000175161
BioGRIDCADM2
STRING (EMBL)CADM2
ZODIACCADM2
Ontologies - Pathways
QuickGOQ8N3J6
Ontology : AmiGOreceptor activity  receptor binding  plasma membrane  integral component of plasma membrane  cell-cell adherens junction  homophilic cell adhesion via plasma membrane adhesion molecules  heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules  cell recognition  axon  adherens junction organization  protein homodimerization activity  synapse  cell adhesion molecule binding  
Ontology : EGO-EBIreceptor activity  receptor binding  plasma membrane  integral component of plasma membrane  cell-cell adherens junction  homophilic cell adhesion via plasma membrane adhesion molecules  heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules  cell recognition  axon  adherens junction organization  protein homodimerization activity  synapse  cell adhesion molecule binding  
NDEx NetworkCADM2
Atlas of Cancer Signalling NetworkCADM2
Wikipedia pathwaysCADM2
Orthology - Evolution
OrthoDB253559
GeneTree (enSembl)ENSG00000175161
Phylogenetic Trees/Animal Genes : TreeFamCADM2
HOVERGENQ8N3J6
HOGENOMQ8N3J6
Homologs : HomoloGeneCADM2
Homology/Alignments : Family Browser (UCSC)CADM2
Gene fusions - Rearrangements
Fusion : MitelmanCADM2/FHIT [3p12.1/3p14.2]  
Fusion : MitelmanCPNE8/CADM2 [12q12/3p12.1]  [t(3;12)(p12;q12)]  
Fusion : MitelmanHDLBP/CADM2 [2q37.3/3p12.1]  [t(2;3)(q37;p12)]  
Fusion : MitelmanTEFM/CADM2 [17q11.2/3p12.1]  [t(3;17)(p12;q11)]  
Fusion: TCGAC17orf42 CADM2 3p12.1 BLCA
Fusion: TCGACADM2 3p12.1 FHIT 3p14.2 BRCA
Fusion: TCGACPNE8 12q12 CADM2 3p12.1 LUAD
Fusion: TCGAHDLBP 2q37.3 CADM2 3p12.1 LUAD
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerCADM2 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)CADM2
dbVarCADM2
ClinVarCADM2
1000_GenomesCADM2 
Exome Variant ServerCADM2
ExAC (Exome Aggregation Consortium)CADM2 (select the gene name)
Genetic variants : HAPMAP253559
Genomic Variants (DGV)CADM2 [DGVbeta]
DECIPHERCADM2 [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisCADM2 
Mutations
ICGC Data PortalCADM2 
TCGA Data PortalCADM2 
Broad Tumor PortalCADM2
OASIS PortalCADM2 [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICCADM2  [overview]  [genome browser]  [tissue]  [distribution]  
Mutations and Diseases : HGMDCADM2
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
BioMutasearch CADM2
DgiDB (Drug Gene Interaction Database)CADM2
DoCM (Curated mutations)CADM2 (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)CADM2 (select a term)
intoGenCADM2
Cancer3DCADM2(select the gene name)
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM609938   
Orphanet
MedgenCADM2
Genetic Testing Registry CADM2
NextProtQ8N3J6 [Medical]
TSGene253559
GENETestsCADM2
Huge Navigator CADM2 [HugePedia]
snp3D : Map Gene to Disease253559
BioCentury BCIQCADM2
ClinGenCADM2
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD253559
Chemical/Pharm GKB GenePA162380882
Clinical trialCADM2
Miscellaneous
canSAR (ICR)CADM2 (select the gene name)
Probes
Litterature
PubMed19 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineCADM2
EVEXCADM2
GoPubMedCADM2
iHOPCADM2
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

Search in all EBI   NCBI

© Atlas of Genetics and Cytogenetics in Oncology and Haematology
indexed on : Fri May 19 12:08:40 CEST 2017

Home   Genes   Leukemias   Solid Tumors   Cancer-Prone   Deep Insight   Case Reports   Journals  Portal   Teaching   

For comments and suggestions or contributions, please contact us

jlhuret@AtlasGeneticsOncology.org.