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CADM2 (cell adhesion molecule 2)

Identity

Alias (NCBI)IGSF4D
NECL3
Necl-3
SynCAM 2
synCAM2
HGNC (Hugo) CADM2
HGNC Alias symbNECL3
Necl-3
SynCAM2
HGNC Alias namenectin-like 3
HGNC Previous nameIGSF4D
HGNC Previous nameimmunoglobulin superfamily, member 4D
LocusID (NCBI) 253559
Atlas_Id 52479
Location 3p12.1  [Link to chromosome band 3p12]
Location_base_pair Starts at 85726244 and ends at 86074429 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2017)
Data from Atlas, Mitelman, Cosmic Fusion, Fusion Cancer, TCGA fusion databases with official HUGO symbols (see references in chromosomal bands)
CADM2 (3p12.1) / CADM2 (3p12.1)CADM2 (3p12.1) / FARP1 (13q32.2)CADM2 (3p12.1) / FHIT (3p14.2)
CADM2 (3p12.1) / FTX (Xq13.2)CADM2 (3p12.1) / PPP1CC (12q24.11)CPNE8 (12q12) / CADM2 (3p12.1)
DAB1 (1p32.2) / CADM2 (3p12.1)HDLBP (2q37.3) / CADM2 (3p12.1)PTPRN2 (7q36.3) / CADM2 (3p12.1)
ROBO2 (3p12.3) / CADM2 (3p12.1)SLN (11q22.3) / CADM2 (3p12.1)TEFM (17q11.2) / CADM2 (3p12.1)
TFEB (6p21.1) / CADM2 (3p12.1)C17orf42 CADM2 3p12.1CADM2 3p12.1 / FHIT 3p14.2
CPNE8 12q12 / CADM2 3p12.1HDLBP 2q37.3 / CADM2 3p12.1

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 



External links

 

Nomenclature
HGNC (Hugo)CADM2   29849
Cards
Entrez_Gene (NCBI)CADM2    cell adhesion molecule 2
AliasesIGSF4D; NECL3; Necl-3; SynCAM; 
synCAM2
GeneCards (Weizmann)CADM2
Ensembl hg19 (Hinxton)ENSG00000175161 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000175161 [Gene_View]  ENSG00000175161 [Sequence]  chr3:85726244-86074429 [Contig_View]  CADM2 [Vega]
ICGC DataPortalENSG00000175161
TCGA cBioPortalCADM2
AceView (NCBI)CADM2
Genatlas (Paris)CADM2
SOURCE (Princeton)CADM2
Genetics Home Reference (NIH)CADM2
Genomic and cartography
GoldenPath hg38 (UCSC)CADM2  -     chr3:85726244-86074429 +  3p12.1   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)CADM2  -     3p12.1   [Description]    (hg19-Feb_2009)
GoldenPathCADM2 - 3p12.1 [CytoView hg19]  CADM2 - 3p12.1 [CytoView hg38]
ImmunoBaseENSG00000175161
Genome Data Viewer NCBICADM2 [Mapview hg19]  
OMIM609938   
Gene and transcription
Genbank (Entrez)AB646739 AB646740 AB646741 AB646742 AB646743
RefSeq transcript (Entrez)NM_001167674 NM_001167675 NM_001256502 NM_001256503 NM_001256504 NM_001256505 NM_001375960 NM_001375961 NM_001375964 NM_001375967 NM_001375968 NM_001381963 NM_001381964 NM_153184
Consensus coding sequences : CCDS (NCBI)CADM2
Gene ExpressionCADM2 [ NCBI-GEO ]   CADM2 [ EBI - ARRAY_EXPRESS ]   CADM2 [ SEEK ]   CADM2 [ MEM ]
Gene Expression Viewer (FireBrowse)CADM2 [ Firebrowse - Broad ]
GenevisibleExpression of CADM2 in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)253559
GTEX Portal (Tissue expression)CADM2
Human Protein AtlasENSG00000175161-CADM2 [pathology]   [cell]   [tissue]
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ8N3J6   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtQ8N3J6  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProQ8N3J6
PhosPhoSitePlusQ8N3J6
Domaine pattern : Prosite (Expaxy)IG_LIKE (PS50835)   
Domains : Interpro (EBI)CD80_C2-set    Ig-like_dom    Ig-like_dom_sf    Ig-like_fold    Ig_sub    Ig_sub2    Ig_V-set    Neurexin-like   
Domain families : Pfam (Sanger)C2-set_2 (PF08205)    V-set (PF07686)   
Domain families : Pfam (NCBI)pfam08205    pfam07686   
Domain families : Smart (EMBL)4.1m (SM00294)  IG (SM00409)  IGc2 (SM00408)  
Conserved Domain (NCBI)CADM2
SuperfamilyQ8N3J6
AlphaFold pdb e-kbQ8N3J6   
Human Protein Atlas [tissue]ENSG00000175161-CADM2 [tissue]
HPRD11046
Protein Interaction databases
DIP (DOE-UCLA)Q8N3J6
IntAct (EBI)Q8N3J6
BioGRIDCADM2
STRING (EMBL)CADM2
ZODIACCADM2
Ontologies - Pathways
QuickGOQ8N3J6
Ontology : AmiGOplasma membrane  cell adhesion  integral component of membrane  axon  adherens junction organization  synapse  
Ontology : EGO-EBIplasma membrane  cell adhesion  integral component of membrane  axon  adherens junction organization  synapse  
NDEx NetworkCADM2
Atlas of Cancer Signalling NetworkCADM2
Wikipedia pathwaysCADM2
Orthology - Evolution
OrthoDB253559
GeneTree (enSembl)ENSG00000175161
Phylogenetic Trees/Animal Genes : TreeFamCADM2
Homologs : HomoloGeneCADM2
Homology/Alignments : Family Browser (UCSC)CADM2
Gene fusions - Rearrangements
Fusion : MitelmanCADM2/FHIT [3p12.1/3p14.2]  
Fusion : MitelmanCPNE8/CADM2 [12q12/3p12.1]  
Fusion : MitelmanHDLBP/CADM2 [2q37.3/3p12.1]  
Fusion : MitelmanTEFM/CADM2 [17q11.2/3p12.1]  
Fusion : QuiverCADM2
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerCADM2 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)CADM2
dbVarCADM2
ClinVarCADM2
MonarchCADM2
1000_GenomesCADM2 
Exome Variant ServerCADM2
GNOMAD BrowserENSG00000175161
Varsome BrowserCADM2
ACMGCADM2 variants
VarityQ8N3J6
Genomic Variants (DGV)CADM2 [DGVbeta]
DECIPHERCADM2 [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisCADM2 
Mutations
ICGC Data PortalCADM2 
TCGA Data PortalCADM2 
Broad Tumor PortalCADM2
OASIS PortalCADM2 [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICCADM2  [overview]  [genome browser]  [tissue]  [distribution]  
Somatic Mutations in Cancer : COSMIC3DCADM2
Mutations and Diseases : HGMDCADM2
LOVD (Leiden Open Variation Database)[gene] [transcripts] [variants]
BioMutaCADM2
DgiDB (Drug Gene Interaction Database)CADM2
DoCM (Curated mutations)CADM2
CIViC (Clinical Interpretations of Variants in Cancer)CADM2
Cancer3DCADM2
Impact of mutations[PolyPhen2] [Provean] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM609938   
Orphanet
DisGeNETCADM2
MedgenCADM2
Genetic Testing Registry CADM2
NextProtQ8N3J6 [Medical]
GENETestsCADM2
Target ValidationCADM2
Huge Navigator CADM2 [HugePedia]
ClinGenCADM2
Clinical trials, drugs, therapy
MyCancerGenomeCADM2
Protein Interactions : CTDCADM2
Pharm GKB GenePA162380882
PharosQ8N3J6
Clinical trialCADM2
Miscellaneous
canSAR (ICR)CADM2
HarmonizomeCADM2
DataMed IndexCADM2
Probes
Litterature
PubMed28 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
EVEXCADM2
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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indexed on : Mon Oct 4 15:02:02 CEST 2021

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