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CADM3 (cell adhesion molecule 3)

Identity

Alias_namesIGSF4B
immunoglobulin superfamily
Alias_symbol (synonym)BIgR
FLJ10698
TSLL1
NECL1
SynCAM3
Necl-1
Other aliassynCAM3
HGNC (Hugo) CADM3
LocusID (NCBI) 57863
Atlas_Id 51045
Location 1q23.2  [Link to chromosome band 1q23]
Location_base_pair Starts at 159171564 and ends at 159203313 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2016)
CADM3 (1q23.2) / CALM3 (19q13.32)CADM3 (1q23.2) / DDX42 (17q23.3)DDX42 (17q23.3) / CADM3 (1q23.2)
TADA1 (1q24.1) / CADM3 (1q23.2)TADA1 1q24.1 / CADM3 1q23.2

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


External links

Nomenclature
HGNC (Hugo)CADM3   17601
Cards
Entrez_Gene (NCBI)CADM3  57863  cell adhesion molecule 3
AliasesBIgR; IGSF4B; NECL1; Necl-1; 
TSLL1; synCAM3
GeneCards (Weizmann)CADM3
Ensembl hg19 (Hinxton)ENSG00000162706 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000162706 [Gene_View]  chr1:159171564-159203313 [Contig_View]  CADM3 [Vega]
ICGC DataPortalENSG00000162706
TCGA cBioPortalCADM3
AceView (NCBI)CADM3
Genatlas (Paris)CADM3
WikiGenes57863
SOURCE (Princeton)CADM3
Genetics Home Reference (NIH)CADM3
Genomic and cartography
GoldenPath hg38 (UCSC)CADM3  -     chr1:159171564-159203313 +  1q23.2   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)CADM3  -     1q23.2   [Description]    (hg19-Feb_2009)
EnsemblCADM3 - 1q23.2 [CytoView hg19]  CADM3 - 1q23.2 [CytoView hg38]
Mapping of homologs : NCBICADM3 [Mapview hg19]  CADM3 [Mapview hg38]
OMIM609743   
Gene and transcription
Genbank (Entrez)AF062733 AF363367 AF529206 AK001560 AK289541
RefSeq transcript (Entrez)NM_001127173 NM_001346510 NM_021189
RefSeq genomic (Entrez)
Consensus coding sequences : CCDS (NCBI)CADM3
Cluster EST : UnigeneHs.365689 [ NCBI ]
CGAP (NCI)Hs.365689
Alternative Splicing GalleryENSG00000162706
Gene ExpressionCADM3 [ NCBI-GEO ]   CADM3 [ EBI - ARRAY_EXPRESS ]   CADM3 [ SEEK ]   CADM3 [ MEM ]
Gene Expression Viewer (FireBrowse)CADM3 [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevisibleExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)57863
GTEX Portal (Tissue expression)CADM3
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ8N126   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtQ8N126  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProQ8N126
Splice isoforms : SwissVarQ8N126
PhosPhoSitePlusQ8N126
Domaine pattern : Prosite (Expaxy)IG_LIKE (PS50835)   
Domains : Interpro (EBI)CD80_C2-set    Ig-like_dom    Ig-like_fold    Ig_I-set    Ig_sub    Ig_sub2    Neurexin-like   
Domain families : Pfam (Sanger)C2-set_2 (PF08205)    I-set (PF07679)   
Domain families : Pfam (NCBI)pfam08205    pfam07679   
Domain families : Smart (EMBL)4.1m (SM00294)  IG (SM00409)  IGc2 (SM00408)  
Conserved Domain (NCBI)CADM3
DMDM Disease mutations57863
Blocks (Seattle)CADM3
PDB (SRS)1Z9M   
PDB (PDBSum)1Z9M   
PDB (IMB)1Z9M   
PDB (RSDB)1Z9M   
Structural Biology KnowledgeBase1Z9M   
SCOP (Structural Classification of Proteins)1Z9M   
CATH (Classification of proteins structures)1Z9M   
SuperfamilyQ8N126
Human Protein AtlasENSG00000162706
Peptide AtlasQ8N126
HPRD13733
IPIIPI00166048   IPI00009619   IPI00383615   
Protein Interaction databases
DIP (DOE-UCLA)Q8N126
IntAct (EBI)Q8N126
FunCoupENSG00000162706
BioGRIDCADM3
STRING (EMBL)CADM3
ZODIACCADM3
Ontologies - Pathways
QuickGOQ8N126
Ontology : AmiGOreceptor activity  receptor binding  plasma membrane  integral component of plasma membrane  cell-cell junction  cell-cell adherens junction  homophilic cell adhesion via plasma membrane adhesion molecules  homophilic cell adhesion via plasma membrane adhesion molecules  heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules  heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules  cell recognition  protein localization  adherens junction organization  protein homodimerization activity  protein homodimerization activity  cell adhesion molecule binding  
Ontology : EGO-EBIreceptor activity  receptor binding  plasma membrane  integral component of plasma membrane  cell-cell junction  cell-cell adherens junction  homophilic cell adhesion via plasma membrane adhesion molecules  homophilic cell adhesion via plasma membrane adhesion molecules  heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules  heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules  cell recognition  protein localization  adherens junction organization  protein homodimerization activity  protein homodimerization activity  cell adhesion molecule binding  
Pathways : KEGGCell adhesion molecules (CAMs)   
NDEx NetworkCADM3
Atlas of Cancer Signalling NetworkCADM3
Wikipedia pathwaysCADM3
Orthology - Evolution
OrthoDB57863
GeneTree (enSembl)ENSG00000162706
Phylogenetic Trees/Animal Genes : TreeFamCADM3
HOVERGENQ8N126
HOGENOMQ8N126
Homologs : HomoloGeneCADM3
Homology/Alignments : Family Browser (UCSC)CADM3
Gene fusions - Rearrangements
Fusion : MitelmanTADA1/CADM3 [1q24.1/1q23.2]  [t(1;1)(q23;q24)]  
Fusion: TCGATADA1 1q24.1 CADM3 1q23.2 LUAD
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerCADM3 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)CADM3
dbVarCADM3
ClinVarCADM3
1000_GenomesCADM3 
Exome Variant ServerCADM3
ExAC (Exome Aggregation Consortium)CADM3 (select the gene name)
Genetic variants : HAPMAP57863
Genomic Variants (DGV)CADM3 [DGVbeta]
DECIPHERCADM3 [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisCADM3 
Mutations
ICGC Data PortalCADM3 
TCGA Data PortalCADM3 
Broad Tumor PortalCADM3
OASIS PortalCADM3 [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICCADM3  [overview]  [genome browser]  [tissue]  [distribution]  
Mutations and Diseases : HGMDCADM3
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD - Leiden Open Variation Database
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
BioMutasearch CADM3
DgiDB (Drug Gene Interaction Database)CADM3
DoCM (Curated mutations)CADM3 (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)CADM3 (select a term)
intoGenCADM3
Cancer3DCADM3(select the gene name)
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM609743   
Orphanet
MedgenCADM3
Genetic Testing Registry CADM3
NextProtQ8N126 [Medical]
TSGene57863
GENETestsCADM3
Target ValidationCADM3
Huge Navigator CADM3 [HugePedia]
snp3D : Map Gene to Disease57863
BioCentury BCIQCADM3
ClinGenCADM3
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD57863
Chemical/Pharm GKB GenePA162380906
Clinical trialCADM3
Miscellaneous
canSAR (ICR)CADM3 (select the gene name)
Probes
Litterature
PubMed27 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineCADM3
EVEXCADM3
GoPubMedCADM3
iHOPCADM3
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

Search in all EBI   NCBI

© Atlas of Genetics and Cytogenetics in Oncology and Haematology
indexed on : Tue Aug 1 16:56:40 CEST 2017

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