Atlas of Genetics and Cytogenetics in Oncology and Haematology


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CALCA (calcitonin related polypeptide alpha)

Identity

Alias_namesCALC1
calcitonin 1
Other aliasCGRP
CGRP-I
CGRP1
CT
KC
PCT
HGNC (Hugo) CALCA
LocusID (NCBI) 796
Atlas_Id 43682
Location 11p15.2  [Link to chromosome band 11p15]
Location_base_pair Starts at 14968502 and ends at 14972286 bp from pter ( according to hg38-Dec_2013)

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


External links

Nomenclature
HGNC (Hugo)CALCA   1437
LRG (Locus Reference Genomic)LRG_13
Cards
Entrez_Gene (NCBI)CALCA  796  calcitonin related polypeptide alpha
AliasesCALC1; CGRP; CGRP-I; CGRP1; 
CT; KC; PCT
GeneCards (Weizmann)CALCA
Ensembl hg19 (Hinxton)ENSG00000110680 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000110680 [Gene_View]  chr11:14968502-14972286 [Contig_View]  CALCA [Vega]
ICGC DataPortalENSG00000110680
TCGA cBioPortalCALCA
AceView (NCBI)CALCA
Genatlas (Paris)CALCA
WikiGenes796
SOURCE (Princeton)CALCA
Genetics Home Reference (NIH)CALCA
Genomic and cartography
GoldenPath hg38 (UCSC)CALCA  -     chr11:14968502-14972286 -  11p15.2   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)CALCA  -     11p15.2   [Description]    (hg19-Feb_2009)
EnsemblCALCA - 11p15.2 [CytoView hg19]  CALCA - 11p15.2 [CytoView hg38]
Mapping of homologs : NCBICALCA [Mapview hg19]  CALCA [Mapview hg38]
OMIM114130   
Gene and transcription
Genbank (Entrez)BC069684 BC069704 BC069760 BC069778 BC093753
RefSeq transcript (Entrez)NM_001033952 NM_001033953 NM_001741
RefSeq genomic (Entrez)
Consensus coding sequences : CCDS (NCBI)CALCA
Cluster EST : UnigeneHs.37058 [ NCBI ]
CGAP (NCI)Hs.37058
Alternative Splicing GalleryENSG00000110680
Gene ExpressionCALCA [ NCBI-GEO ]   CALCA [ EBI - ARRAY_EXPRESS ]   CALCA [ SEEK ]   CALCA [ MEM ]
Gene Expression Viewer (FireBrowse)CALCA [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevisibleExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)796
GTEX Portal (Tissue expression)CALCA
Protein : pattern, domain, 3D structure
UniProt/SwissProtP06881   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtP06881  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProP06881
Splice isoforms : SwissVarP06881
PhosPhoSitePlusP06881
Domaine pattern : Prosite (Expaxy)CALCITONIN (PS00258)   
Domains : Interpro (EBI)Calcitonin-like    Calcitonin/adrenomedullin    Calcitonin_CS    Calcitonin_gene-rel_peptide    Calcitonin_peptide-like   
Domain families : Pfam (Sanger)Calc_CGRP_IAPP (PF00214)   
Domain families : Pfam (NCBI)pfam00214   
Domain families : Smart (EMBL)CALCITONIN (SM00113)  
Conserved Domain (NCBI)CALCA
DMDM Disease mutations796
Blocks (Seattle)CALCA
PDB (SRS)1LS7   
PDB (PDBSum)1LS7   
PDB (IMB)1LS7   
PDB (RSDB)1LS7   
Structural Biology KnowledgeBase1LS7   
SCOP (Structural Classification of Proteins)1LS7   
CATH (Classification of proteins structures)1LS7   
SuperfamilyP06881
Human Protein AtlasENSG00000110680
Peptide AtlasP06881
HPRD00238
IPIIPI00000914   IPI00215863   IPI00027855   
Protein Interaction databases
DIP (DOE-UCLA)P06881
IntAct (EBI)P06881
FunCoupENSG00000110680
BioGRIDCALCA
STRING (EMBL)CALCA
ZODIACCALCA
Ontologies - Pathways
QuickGOP06881
Ontology : AmiGOartery vasodilation involved in baroreceptor response to increased systemic arterial blood pressure  regulation of heart rate  monocyte chemotaxis  hormone activity  protein binding  extracellular region  extracellular space  nucleus  cytoplasm  inflammatory response  adenylate cyclase-activating G-protein coupled receptor signaling pathway  activation of adenylate cyclase activity  positive regulation of cytosolic calcium ion concentration  neuropeptide signaling pathway  embryo implantation  aging  feeding behavior  response to heat  negative regulation of ossification  negative regulation of neurological system process  calcitonin receptor binding  activation of protein kinase activity  identical protein binding  neuronal cell body  terminal bouton  cellular protein metabolic process  positive regulation of adenylate cyclase activity  positive regulation of ossification  negative regulation of bone resorption  negative regulation of transcription, DNA-templated  negative regulation of smooth muscle contraction  response to pain  detection of temperature stimulus involved in sensory perception of pain  positive regulation of cytosolic calcium ion concentration involved in phospholipase C-activating G-protein coupled signaling pathway  cellular response to tumor necrosis factor  cellular response to nerve growth factor stimulus  
Ontology : EGO-EBIartery vasodilation involved in baroreceptor response to increased systemic arterial blood pressure  regulation of heart rate  monocyte chemotaxis  hormone activity  protein binding  extracellular region  extracellular space  nucleus  cytoplasm  inflammatory response  adenylate cyclase-activating G-protein coupled receptor signaling pathway  activation of adenylate cyclase activity  positive regulation of cytosolic calcium ion concentration  neuropeptide signaling pathway  embryo implantation  aging  feeding behavior  response to heat  negative regulation of ossification  negative regulation of neurological system process  calcitonin receptor binding  activation of protein kinase activity  identical protein binding  neuronal cell body  terminal bouton  cellular protein metabolic process  positive regulation of adenylate cyclase activity  positive regulation of ossification  negative regulation of bone resorption  negative regulation of transcription, DNA-templated  negative regulation of smooth muscle contraction  response to pain  detection of temperature stimulus involved in sensory perception of pain  positive regulation of cytosolic calcium ion concentration involved in phospholipase C-activating G-protein coupled signaling pathway  cellular response to tumor necrosis factor  cellular response to nerve growth factor stimulus  
NDEx NetworkCALCA
Atlas of Cancer Signalling NetworkCALCA
Wikipedia pathwaysCALCA
Orthology - Evolution
OrthoDB796
GeneTree (enSembl)ENSG00000110680
Phylogenetic Trees/Animal Genes : TreeFamCALCA
HOVERGENP06881
HOGENOMP06881
Homologs : HomoloGeneCALCA
Homology/Alignments : Family Browser (UCSC)CALCA
Gene fusions - Rearrangements
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerCALCA [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)CALCA
dbVarCALCA
ClinVarCALCA
1000_GenomesCALCA 
Exome Variant ServerCALCA
ExAC (Exome Aggregation Consortium)CALCA (select the gene name)
Genetic variants : HAPMAP796
Genomic Variants (DGV)CALCA [DGVbeta]
DECIPHERCALCA [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisCALCA 
Mutations
ICGC Data PortalCALCA 
TCGA Data PortalCALCA 
Broad Tumor PortalCALCA
OASIS PortalCALCA [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICCALCA  [overview]  [genome browser]  [tissue]  [distribution]  
Mutations and Diseases : HGMDCALCA
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD - Leiden Open Variation Database
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
BioMutasearch CALCA
DgiDB (Drug Gene Interaction Database)CALCA
DoCM (Curated mutations)CALCA (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)CALCA (select a term)
intoGenCALCA
Cancer3DCALCA(select the gene name)
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM114130   
Orphanet
MedgenCALCA
Genetic Testing Registry CALCA
NextProtP06881 [Medical]
TSGene796
GENETestsCALCA
Huge Navigator CALCA [HugePedia]
snp3D : Map Gene to Disease796
BioCentury BCIQCALCA
ClinGenCALCA
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD796
Chemical/Pharm GKB GenePA26029
Clinical trialCALCA
Miscellaneous
canSAR (ICR)CALCA (select the gene name)
Probes
Litterature
PubMed364 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineCALCA
EVEXCALCA
GoPubMedCALCA
iHOPCALCA
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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indexed on : Fri May 19 12:08:41 CEST 2017

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