CALCB (calcitonin related polypeptide beta)

2016-10-01 Affiliation

Identity

HGNC

CALCB

LOCATION

11p15.2

LOCUSID

797

ALIAS

CALC2,CGRP-II,CGRP2

Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, contribute in submission tool

Other Information

Locus ID:

NCBI: 797
MIM: 114160
HGNC: 1438
Ensembl: ENSG00000175868

Variants:

dbSNP: 797
ClinVar: 797
TCGA: ENSG00000175868
COSMIC: CALCB

RNA/Proteins

Gene ID	Transcript ID	Uniprot
ENSG00000175868	ENST00000324229	P10092
ENSG00000175868	ENST00000523376	E7ESF5
ENSG00000175868	ENST00000533448	P10092

Expression (GTEx)

Adipose - Subcutaneous

Adipose - Visceral

Adrenal Gland

Artery - Aorta

Artery - Tibial

Bladder

Brain - Amygdala

Brain - Anterior cingulate cortex

Brain - Caudate

Brain - Cerebellar Hemisphere

Brain - Cerebellum

Brain - Cortex

Brain - Frontal Cortex

Brain - Hippocampus

Brain - Hypothalamus

Brain - Nucleus accumbens

Brain - Putamen

Brain - Spinal cord

Brain - Substantia nigra

Breast - Mammary Tissue

Cells - Cultured fibroblasts

Cells - EBV - transformed lymphocytes

Cervix - Ectocervix

Cervix - Endocervix

Colon - Sigmoid

Colon - Transverse

Esophagus - Gastroesophageal Junction

Esophagus - Mucosa

Esophagus - Muscularis

Fallopian Tube

Heart - Atrial Appendage

Heart - Left Ventricle

Kidney - Cortex

Kidney - Medulla

Liver

Lung

Minor Salivary Gland

Muscle - Skeletal

Nerve - Tibial

Ovary

Pancreas

Pituitary

Prostate

Skin - Not Sun Exposed

Skin - Sun Exposed

Small Intestine - Terminal Ileum

Spleen

Stomach

Testis

Thyroid

Uterus

Vagina

Whole Blood

Pathways

Pathway	Source	External ID
Signal Transduction	REACTOME	R-HSA-162582
Signaling by GPCR	REACTOME	R-HSA-372790
GPCR ligand binding	REACTOME	R-HSA-500792
Class B/2 (Secretin family receptors)	REACTOME	R-HSA-373080
Calcitonin-like ligand receptors	REACTOME	R-HSA-419812
GPCR downstream signaling	REACTOME	R-HSA-388396
G alpha (s) signalling events	REACTOME	R-HSA-418555

References

Pubmed ID	Year	Title	Citations
21641113	2011	Keratinocyte expression of calcitonin gene-related peptide β: implications for neuropathic and inflammatory pain mechanisms.	36
19086053	2009	Identification of new putative susceptibility genes for several psychiatric disorders by association analysis of regulatory and non-synonymous SNPs of 306 genes involved in neurotransmission and neurodevelopment.	34
15761041	2005	Autocrine/paracrine role of inflammation-mediated calcitonin gene-related peptide and adrenomedullin expression in human adipose tissue.	31
19192276	2009	Calcitonin gene-related peptide stimulates proliferation of alveolar epithelial cells.	6
26967115	2016	Searching for novel ATF4 target genes in human hepatoma cells by microarray analysis.	3

Citation

Dessen P

CALCB (calcitonin related polypeptide beta)

Atlas Genet Cytogenet Oncol Haematol. 2016-10-01

Online version: http://atlasgeneticsoncology.org/gene/56135/calcb