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CALCR (calcitonin receptor)

Identity

Alias_symbol (synonym)CTR
Other aliasCRT
CT-R
CTR1
HGNC (Hugo) CALCR
LocusID (NCBI) 799
Atlas_Id 49768
Location 7q21.3  [Link to chromosome band 7q21]
Location_base_pair Starts at 93424487 and ends at 93574730 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2017)
Data from Atlas, Mitelman, Cosmic Fusion, Fusion Cancer, TCGA fusion databases with official HUGO symbols (see references in chromosomal bands)
CALCR (7q21.3) / SEPT11 (4q21.1)

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


External links

Nomenclature
HGNC (Hugo)CALCR   1440
LRG (Locus Reference Genomic)LRG_1037
Cards
Entrez_Gene (NCBI)CALCR  799  calcitonin receptor
AliasesCRT; CT-R; CTR; CTR1
GeneCards (Weizmann)CALCR
Ensembl hg19 (Hinxton)ENSG00000004948 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000004948 [Gene_View]  chr7:93424487-93574730 [Contig_View]  CALCR [Vega]
ICGC DataPortalENSG00000004948
TCGA cBioPortalCALCR
AceView (NCBI)CALCR
Genatlas (Paris)CALCR
WikiGenes799
SOURCE (Princeton)CALCR
Genetics Home Reference (NIH)CALCR
Genomic and cartography
GoldenPath hg38 (UCSC)CALCR  -     chr7:93424487-93574730 -  7q21.3   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)CALCR  -     7q21.3   [Description]    (hg19-Feb_2009)
EnsemblCALCR - 7q21.3 [CytoView hg19]  CALCR - 7q21.3 [CytoView hg38]
Mapping of homologs : NCBICALCR [Mapview hg19]  CALCR [Mapview hg38]
OMIM114131   166710   
Gene and transcription
Genbank (Entrez)AB022177 AB022178 AJ831406 AJ831407 AK313996
RefSeq transcript (Entrez)NM_001164737 NM_001164738 NM_001742
RefSeq genomic (Entrez)
Consensus coding sequences : CCDS (NCBI)CALCR
Cluster EST : UnigeneHs.489127 [ NCBI ]
CGAP (NCI)Hs.489127
Alternative Splicing GalleryENSG00000004948
Gene ExpressionCALCR [ NCBI-GEO ]   CALCR [ EBI - ARRAY_EXPRESS ]   CALCR [ SEEK ]   CALCR [ MEM ]
Gene Expression Viewer (FireBrowse)CALCR [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevestigatorExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)799
GTEX Portal (Tissue expression)CALCR
Human Protein AtlasENSG00000004948-CALCR [pathology]   [cell]   [tissue]
Protein : pattern, domain, 3D structure
UniProt/SwissProtP30988   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtP30988  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProP30988
Splice isoforms : SwissVarP30988
PhosPhoSitePlusP30988
Domaine pattern : Prosite (Expaxy)G_PROTEIN_RECEP_F2_1 (PS00649)    G_PROTEIN_RECEP_F2_2 (PS00650)    G_PROTEIN_RECEP_F2_3 (PS50227)    G_PROTEIN_RECEP_F2_4 (PS50261)   
Domains : Interpro (EBI)GCPR_2_calcitonin_rcpt_fam    GPCR_2-like    GPCR_2_calcitonin_rcpt    GPCR_2_extracellular_dom    GPCR_2_secretin-like    GPCR_2_secretin-like_CS   
Domain families : Pfam (Sanger)7tm_2 (PF00002)    HRM (PF02793)   
Domain families : Pfam (NCBI)pfam00002    pfam02793   
Domain families : Smart (EMBL)HormR (SM00008)  
Conserved Domain (NCBI)CALCR
DMDM Disease mutations799
Blocks (Seattle)CALCR
PDB (SRS)5II0   
PDB (PDBSum)5II0   
PDB (IMB)5II0   
PDB (RSDB)5II0   
Structural Biology KnowledgeBase5II0   
SCOP (Structural Classification of Proteins)5II0   
CATH (Classification of proteins structures)5II0   
SuperfamilyP30988
Human Protein Atlas [tissue]ENSG00000004948-CALCR [tissue]
Peptide AtlasP30988
HPRD00239
IPIIPI00187004   IPI00419304   IPI01015083   IPI00925992   IPI00925772   
Protein Interaction databases
DIP (DOE-UCLA)P30988
IntAct (EBI)P30988
FunCoupENSG00000004948
BioGRIDCALCR
STRING (EMBL)CALCR
ZODIACCALCR
Ontologies - Pathways
QuickGOP30988
Ontology : AmiGOreceptor activity  calcitonin receptor activity  protein binding  plasma membrane  integral component of plasma membrane  cell surface receptor signaling pathway  adenylate cyclase-activating G-protein coupled receptor signaling pathway  adenylate cyclase-activating G-protein coupled receptor signaling pathway  activation of adenylate cyclase activity  protein transporter activity  protein transport  positive regulation of cAMP biosynthetic process  receptor internalization  calcitonin binding  calcitonin binding  calcitonin binding  positive regulation of adenylate cyclase activity  response to glucocorticoid  protein localization to plasma membrane  
Ontology : EGO-EBIreceptor activity  calcitonin receptor activity  protein binding  plasma membrane  integral component of plasma membrane  cell surface receptor signaling pathway  adenylate cyclase-activating G-protein coupled receptor signaling pathway  adenylate cyclase-activating G-protein coupled receptor signaling pathway  activation of adenylate cyclase activity  protein transporter activity  protein transport  positive regulation of cAMP biosynthetic process  receptor internalization  calcitonin binding  calcitonin binding  calcitonin binding  positive regulation of adenylate cyclase activity  response to glucocorticoid  protein localization to plasma membrane  
Pathways : KEGGNeuroactive ligand-receptor interaction    Osteoclast differentiation   
NDEx NetworkCALCR
Atlas of Cancer Signalling NetworkCALCR
Wikipedia pathwaysCALCR
Orthology - Evolution
OrthoDB799
GeneTree (enSembl)ENSG00000004948
Phylogenetic Trees/Animal Genes : TreeFamCALCR
HOVERGENP30988
HOGENOMP30988
Homologs : HomoloGeneCALCR
Homology/Alignments : Family Browser (UCSC)CALCR
Gene fusions - Rearrangements
Fusion: Tumor Portal CALCR
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerCALCR [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)CALCR
dbVarCALCR
ClinVarCALCR
1000_GenomesCALCR 
Exome Variant ServerCALCR
ExAC (Exome Aggregation Consortium)ENSG00000004948
GNOMAD BrowserENSG00000004948
Genetic variants : HAPMAP799
Genomic Variants (DGV)CALCR [DGVbeta]
DECIPHERCALCR [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisCALCR 
Mutations
ICGC Data PortalCALCR 
TCGA Data PortalCALCR 
Broad Tumor PortalCALCR
OASIS PortalCALCR [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICCALCR  [overview]  [genome browser]  [tissue]  [distribution]  
Mutations and Diseases : HGMDCALCR
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD - Leiden Open Variation Database
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
BioMutasearch CALCR
DgiDB (Drug Gene Interaction Database)CALCR
DoCM (Curated mutations)CALCR (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)CALCR (select a term)
intoGenCALCR
Cancer3DCALCR(select the gene name)
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM114131    166710   
Orphanet
MedgenCALCR
Genetic Testing Registry CALCR
NextProtP30988 [Medical]
TSGene799
GENETestsCALCR
Target ValidationCALCR
Huge Navigator CALCR [HugePedia]
snp3D : Map Gene to Disease799
BioCentury BCIQCALCR
ClinGenCALCR
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD799
Chemical/Pharm GKB GenePA26032
Clinical trialCALCR
Miscellaneous
canSAR (ICR)CALCR (select the gene name)
Probes
Litterature
PubMed88 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineCALCR
EVEXCALCR
GoPubMedCALCR
iHOPCALCR
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

Search in all EBI   NCBI

© Atlas of Genetics and Cytogenetics in Oncology and Haematology
indexed on : Thu Nov 9 12:42:55 CET 2017

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