CALY (calcyon neuron specific vesicular protein)

2014-11-01  

Identity

HGNC
LOCATION
10q26.3
LOCUSID
ALIAS
DRD1IP,NSG3

Other Information

Locus ID:

NCBI: 50632
MIM: 604647
HGNC: 17938
Ensembl: ENSG00000130643

Variants:

dbSNP: 50632
ClinVar: 50632
TCGA: ENSG00000130643
COSMIC: CALY

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000130643ENST00000252939Q9NYX4
ENSG00000130643ENST00000368555Q9NYX4
ENSG00000130643ENST00000368558Q9NYX4

Expression (GTEx)

0
50
100
150
200
250

Pathways

PathwaySourceExternal ID
Dopaminergic synapseKEGGko04728
Dopaminergic synapseKEGGhsa04728

Protein levels (Protein atlas)

Not detected
Low
Medium
High

References

Pubmed IDYearTitleCitations
163854512006A scan of chromosome 10 identifies a novel locus showing strong association with late-onset Alzheimer disease.69
204680642010Association study of 182 candidate genes in anorexia nervosa.30
161726152005Association of the calcyon gene (DRD1IP) with attention deficit/hyperactivity disorder.15
161726152005Association of the calcyon gene (DRD1IP) with attention deficit/hyperactivity disorder.15
165956752006Calcyon, a novel partner of clathrin light chain, stimulates clathrin-mediated endocytosis.15
145343092003Elevated intracellular calcium triggers recruitment of the receptor cross-talk accessory protein calcyon to the plasma membrane.10
193522182009Candidate gene analysis in an on-going genome-wide association study of attention-deficit hyperactivity disorder: suggestive association signals in ADRA1A.10
228436802012Calcyon forms a novel ternary complex with dopamine D1 receptor through PSD-95 protein and plays a role in dopamine receptor internalization.10
147554392004CALCYON gene variation, schizophrenia, and cocaine dependence.6
147554392004CALCYON gene variation, schizophrenia, and cocaine dependence.6

Citation

Dessen P

CALY (calcyon neuron specific vesicular protein)

Atlas Genet Cytogenet Oncol Haematol. 2014-11-01

Online version: http://atlasgeneticsoncology.org/gene/61395/caly