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Taking over the Atlas
Dear Colleagues,
The Atlas, once more, is in great danger, and I will have to proceed to a collective economic lay-off of all the team involved in the Atlas before the begining of April 2015 (a foundation having suddenly withdrawn its commitment to support the Atlas). I ask you herein if any Scientific Society (a Society of Cytogenetics, of Clinical Genetics, of Hematology, or a Cancer Society, or any other...), any University and/or Hospital, any Charity, or any database would be interested in taking over the Atlas, in whole or in part. If taking charge of the whole lot is too big, a consortium of various actors could be the solution (I am myself trying to find partners). Could you please spread the information, contact the relevant authorities, and find partners.
Survival of the Atlas will be critically dependant upon your ability to find solutions (and urgently!).
Kind regards.
Jean-Loup Huret jlhuret@AtlasGeneticsOncology.org
Donations are also welcome
If each casual visitor gives 3 Euros or Dollars, the Atlas is saved in a week !
If each professional gives 100 Euros or Dollars once a year (now), the Atlas is saved in 2 weeks !
Don't let the Atlas imminent demise
Note: we send fiscal receipts for donations equal or above 50 Euros or Dollars

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CAMK1 (calcium/calmodulin-dependent protein kinase I)

Identity

Other namesCAMKI
HGNC (Hugo) CAMK1
LocusID (NCBI) 8536
Location 3p25.3
Location_base_pair Starts at 9799029 and ends at 9811668 bp from pter ( according to hg19-Feb_2009)
Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 

External links

Nomenclature
HGNC (Hugo)CAMK1   1459
Cards
Entrez_Gene (NCBI)CAMK1  8536  calcium/calmodulin-dependent protein kinase I
GeneCards (Weizmann)CAMK1
Ensembl hg19 (Hinxton)ENSG00000134072 [Gene_View]  chr3:9799029-9811668 [Contig_View]  CAMK1 [Vega]
Ensembl hg38 (Hinxton)ENSG00000134072 [Gene_View]  chr3:9799029-9811668 [Contig_View]  CAMK1 [Vega]
ICGC DataPortalENSG00000134072
cBioPortalCAMK1
AceView (NCBI)CAMK1
Genatlas (Paris)CAMK1
WikiGenes8536
SOURCE (Princeton)CAMK1
Genomic and cartography
GoldenPath hg19 (UCSC)CAMK1  -     chr3:9799029-9811668 -  3p25.3   [Description]    (hg19-Feb_2009)
GoldenPath hg38 (UCSC)CAMK1  -     3p25.3   [Description]    (hg38-Dec_2013)
EnsemblCAMK1 - 3p25.3 [CytoView hg19]  CAMK1 - 3p25.3 [CytoView hg38]
Mapping of homologs : NCBICAMK1 [Mapview hg19]  CAMK1 [Mapview hg38]
OMIM604998   
Gene and transcription
Genbank (Entrez)AA724193 AB451277 AB451407 AK314917 BC106754
RefSeq transcript (Entrez)NM_003656
RefSeq genomic (Entrez)NC_000003 NC_018914 NT_022517 NW_004929309
Consensus coding sequences : CCDS (NCBI)CAMK1
Cluster EST : UnigeneHs.434875 [ NCBI ]
CGAP (NCI)Hs.434875
Alternative Splicing : Fast-db (Paris)GSHG0021501
Alternative Splicing GalleryENSG00000134072
Gene ExpressionCAMK1 [ NCBI-GEO ]     CAMK1 [ SEEK ]   CAMK1 [ MEM ]
SOURCE (Princeton)Expression in : [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ14012 (Uniprot)
NextProtQ14012  [Medical]
With graphics : InterProQ14012
Splice isoforms : SwissVarQ14012 (Swissvar)
Catalytic activity : Enzyme2.7.11.17 [ Enzyme-Expasy ]   2.7.11.172.7.11.17 [ IntEnz-EBI ]   2.7.11.17 [ BRENDA ]   2.7.11.17 [ KEGG ]   
Domaine pattern : Prosite (Expaxy)PROTEIN_KINASE_ATP (PS00107)    PROTEIN_KINASE_DOM (PS50011)    PROTEIN_KINASE_ST (PS00108)   
Domains : Interpro (EBI)Ca/CaM-dep_Ca-dep_prot_Kinase    Kinase-like_dom    Prot_kinase_dom    Protein_kinase_ATP_BS    Ser/Thr_dual-sp_kinase    Ser/Thr_kinase_AS   
Related proteins : CluSTrQ14012
Domain families : Pfam (Sanger)Pkinase (PF00069)   
Domain families : Pfam (NCBI)pfam00069   
Domain families : Smart (EMBL)S_TKc (SM00220)  
DMDM Disease mutations8536
Blocks (Seattle)Q14012
PDB (SRS)4FG7    4FG8    4FG9    4FGB   
PDB (PDBSum)4FG7    4FG8    4FG9    4FGB   
PDB (IMB)4FG7    4FG8    4FG9    4FGB   
PDB (RSDB)4FG7    4FG8    4FG9    4FGB   
Human Protein AtlasENSG00000134072
Peptide AtlasQ14012
HPRD05412
IPIIPI00028296   IPI00926719   IPI00927594   IPI00927354   
Protein Interaction databases
DIP (DOE-UCLA)Q14012
IntAct (EBI)Q14012
FunCoupENSG00000134072
BioGRIDCAMK1
IntegromeDBCAMK1
STRING (EMBL)CAMK1
Ontologies - Pathways
QuickGOQ14012
Ontology : AmiGOcalmodulin-dependent protein kinase activity  protein binding  calmodulin binding  ATP binding  nucleus  cytoplasm  protein phosphorylation  nucleocytoplasmic transport  cell cycle  signal transduction  positive regulation of neuron projection development  negative regulation of protein binding  regulation of protein localization  positive regulation of peptidyl-serine phosphorylation  regulation of protein binding  positive regulation of transcription from RNA polymerase II promoter  positive regulation of protein export from nucleus  regulation of muscle cell differentiation  positive regulation of muscle cell differentiation  positive regulation of synapse structural plasticity  positive regulation of syncytium formation by plasma membrane fusion  positive regulation of dendritic spine development  positive regulation of protein serine/threonine kinase activity  positive regulation of protein acetylation  regulation of histone H3-K9 acetylation  
Ontology : EGO-EBIcalmodulin-dependent protein kinase activity  protein binding  calmodulin binding  ATP binding  nucleus  cytoplasm  protein phosphorylation  nucleocytoplasmic transport  cell cycle  signal transduction  positive regulation of neuron projection development  negative regulation of protein binding  regulation of protein localization  positive regulation of peptidyl-serine phosphorylation  regulation of protein binding  positive regulation of transcription from RNA polymerase II promoter  positive regulation of protein export from nucleus  regulation of muscle cell differentiation  positive regulation of muscle cell differentiation  positive regulation of synapse structural plasticity  positive regulation of syncytium formation by plasma membrane fusion  positive regulation of dendritic spine development  positive regulation of protein serine/threonine kinase activity  positive regulation of protein acetylation  regulation of histone H3-K9 acetylation  
Pathways : BIOCARTACa++/ Calmodulin-dependent Protein Kinase Activation [Genes]    NFAT and Hypertrophy of the heart (Transcription in the broken heart) [Genes]    Regulation of PGC-1a [Genes]    fMLP induced chemokine gene expression in HMC-1 cells [Genes]    Signal Dependent Regulation of Myogenesis by Corepressor MITR [Genes]    Control of skeletal myogenesis by HDAC & calcium/calmodulin-dependent kinase (CaMK) [Genes]   
Protein Interaction DatabaseCAMK1
DoCM (Curated mutations)CAMK1
Wikipedia pathwaysCAMK1
Gene fusion - rearrangements
Polymorphisms : SNP, variants
NCBI Variation ViewerCAMK1 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)CAMK1
dbVarCAMK1
ClinVarCAMK1
1000_GenomesCAMK1 
Exome Variant ServerCAMK1
SNP (GeneSNP Utah)CAMK1
SNP : HGBaseCAMK1
Genetic variants : HAPMAPCAMK1
Genomic Variants (DGV)CAMK1 [DGVbeta]
Mutations
ICGC Data PortalENSG00000134072 
Somatic Mutations in Cancer : COSMICCAMK1 
CONAN: Copy Number AnalysisCAMK1 
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD - Leiden Open Variation Database
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] 
Diseases
DECIPHER (Syndromes)3:9799029-9811668
Mutations and Diseases : HGMDCAMK1
OMIM604998   
MedgenCAMK1
NextProtQ14012 [Medical]
GENETestsCAMK1
Disease Genetic AssociationCAMK1
Huge Navigator CAMK1 [HugePedia]  CAMK1 [HugeCancerGEM]
snp3D : Map Gene to Disease8536
DGIdb (Drug Gene Interaction db)CAMK1
General knowledge
Homologs : HomoloGeneCAMK1
Homology/Alignments : Family Browser (UCSC)CAMK1
Phylogenetic Trees/Animal Genes : TreeFamCAMK1
Chemical/Protein Interactions : CTD8536
Chemical/Pharm GKB GenePA26048
Clinical trialCAMK1
Cancer Resource (Charite)ENSG00000134072
Other databases
Probes
Litterature
PubMed51 Pubmed reference(s) in Entrez
CoreMineCAMK1
GoPubMedCAMK1
iHOPCAMK1
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

Search in all EBI   NCBI

Contributor(s)

Written09-2002Dessen P, Le Minor S
Updated02-2015Dessen P

© Atlas of Genetics and Cytogenetics in Oncology and Haematology
indexed on : Sat Mar 28 14:56:10 CET 2015

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jlhuret@AtlasGeneticsOncology.org.