Atlas of Genetics and Cytogenetics in Oncology and Haematology


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CAMK1 (calcium/calmodulin dependent protein kinase I)

Identity

Other namesCAMKI
HGNC (Hugo) CAMK1
LocusID (NCBI) 8536
Atlas_Id 905
Location 3p25.3  [Link to chromosome band 3p25]
Location_base_pair Starts at 9799029 and ends at 9811668 bp from pter ( according to hg19-Feb_2009)

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


External links

Nomenclature
HGNC (Hugo)CAMK1   1459
Cards
Entrez_Gene (NCBI)CAMK1  8536  calcium/calmodulin dependent protein kinase I
AliasesCAMKI
GeneCards (Weizmann)CAMK1
Ensembl hg19 (Hinxton)ENSG00000134072 [Gene_View]  chr3:9799029-9811668 [Contig_View]  CAMK1 [Vega]
Ensembl hg38 (Hinxton)ENSG00000134072 [Gene_View]  chr3:9799029-9811668 [Contig_View]  CAMK1 [Vega]
ICGC DataPortalENSG00000134072
TCGA cBioPortalCAMK1
AceView (NCBI)CAMK1
Genatlas (Paris)CAMK1
WikiGenes8536
SOURCE (Princeton)CAMK1
Genomic and cartography
GoldenPath hg19 (UCSC)CAMK1  -     chr3:9799029-9811668 -  3p25.3   [Description]    (hg19-Feb_2009)
GoldenPath hg38 (UCSC)CAMK1  -     3p25.3   [Description]    (hg38-Dec_2013)
EnsemblCAMK1 - 3p25.3 [CytoView hg19]  CAMK1 - 3p25.3 [CytoView hg38]
Mapping of homologs : NCBICAMK1 [Mapview hg19]  CAMK1 [Mapview hg38]
OMIM604998   
Gene and transcription
Genbank (Entrez)AA724193 AB209395 AB451277 AB451407 AK314917
RefSeq transcript (Entrez)NM_003656
RefSeq genomic (Entrez)NC_000003 NC_018914 NT_022517 NW_004929309
Consensus coding sequences : CCDS (NCBI)CAMK1
Cluster EST : UnigeneHs.434875 [ NCBI ]
CGAP (NCI)Hs.434875
Alternative Splicing GalleryENSG00000134072
Gene ExpressionCAMK1 [ NCBI-GEO ]   CAMK1 [ EBI - ARRAY_EXPRESS ]   CAMK1 [ SEEK ]   CAMK1 [ MEM ]
Gene Expression Viewer (FireBrowse)CAMK1 [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevisibleExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)8536
GTEX Portal (Tissue expression)CAMK1
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ14012 (Uniprot)
NextProtQ14012  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProQ14012
Splice isoforms : SwissVarQ14012 (Swissvar)
Catalytic activity : Enzyme2.7.11.17 [ Enzyme-Expasy ]   2.7.11.172.7.11.17 [ IntEnz-EBI ]   2.7.11.17 [ BRENDA ]   2.7.11.17 [ KEGG ]   
PhosPhoSitePlusQ14012
Domaine pattern : Prosite (Expaxy)PROTEIN_KINASE_ATP (PS00107)    PROTEIN_KINASE_DOM (PS50011)    PROTEIN_KINASE_ST (PS00108)   
Domains : Interpro (EBI)Ca/CaM-dep_Ca-dep_prot_Kinase    Kinase-like_dom    Prot_kinase_dom    Protein_kinase_ATP_BS    Ser/Thr_dual-sp_kinase    Ser/Thr_kinase_AS   
Domain families : Pfam (Sanger)Pkinase (PF00069)   
Domain families : Pfam (NCBI)pfam00069   
Domain families : Smart (EMBL)S_TKc (SM00220)  
DMDM Disease mutations8536
Blocks (Seattle)CAMK1
PDB (SRS)4FG7    4FG8    4FG9    4FGB   
PDB (PDBSum)4FG7    4FG8    4FG9    4FGB   
PDB (IMB)4FG7    4FG8    4FG9    4FGB   
PDB (RSDB)4FG7    4FG8    4FG9    4FGB   
Structural Biology KnowledgeBase4FG7    4FG8    4FG9    4FGB   
SCOP (Structural Classification of Proteins)4FG7    4FG8    4FG9    4FGB   
CATH (Classification of proteins structures)4FG7    4FG8    4FG9    4FGB   
SuperfamilyQ14012
Human Protein AtlasENSG00000134072
Peptide AtlasQ14012
HPRD05412
IPIIPI00028296   IPI00926719   IPI00927594   IPI00927354   
Protein Interaction databases
DIP (DOE-UCLA)Q14012
IntAct (EBI)Q14012
FunCoupENSG00000134072
BioGRIDCAMK1
STRING (EMBL)CAMK1
ZODIACCAMK1
Ontologies - Pathways
QuickGOQ14012
Ontology : AmiGOcalmodulin-dependent protein kinase activity  protein binding  calmodulin binding  ATP binding  nucleus  cytoplasm  protein phosphorylation  nucleocytoplasmic transport  cell cycle  signal transduction  positive regulation of neuron projection development  negative regulation of protein binding  regulation of protein localization  positive regulation of peptidyl-serine phosphorylation  regulation of protein binding  positive regulation of transcription from RNA polymerase II promoter  positive regulation of protein export from nucleus  regulation of muscle cell differentiation  positive regulation of muscle cell differentiation  positive regulation of synapse structural plasticity  positive regulation of syncytium formation by plasma membrane fusion  positive regulation of dendritic spine development  positive regulation of protein serine/threonine kinase activity  positive regulation of protein acetylation  regulation of histone H3-K9 acetylation  
Ontology : EGO-EBIcalmodulin-dependent protein kinase activity  protein binding  calmodulin binding  ATP binding  nucleus  cytoplasm  protein phosphorylation  nucleocytoplasmic transport  cell cycle  signal transduction  positive regulation of neuron projection development  negative regulation of protein binding  regulation of protein localization  positive regulation of peptidyl-serine phosphorylation  regulation of protein binding  positive regulation of transcription from RNA polymerase II promoter  positive regulation of protein export from nucleus  regulation of muscle cell differentiation  positive regulation of muscle cell differentiation  positive regulation of synapse structural plasticity  positive regulation of syncytium formation by plasma membrane fusion  positive regulation of dendritic spine development  positive regulation of protein serine/threonine kinase activity  positive regulation of protein acetylation  regulation of histone H3-K9 acetylation  
Pathways : BIOCARTACa++/ Calmodulin-dependent Protein Kinase Activation [Genes]    NFAT and Hypertrophy of the heart (Transcription in the broken heart) [Genes]    Regulation of PGC-1a [Genes]    fMLP induced chemokine gene expression in HMC-1 cells [Genes]    Signal Dependent Regulation of Myogenesis by Corepressor MITR [Genes]    Control of skeletal myogenesis by HDAC & calcium/calmodulin-dependent kinase (CaMK) [Genes]   
NDEx NetworkCAMK1
Atlas of Cancer Signalling NetworkCAMK1
Wikipedia pathwaysCAMK1
Orthology - Evolution
OrthoDB8536
GeneTree (enSembl)ENSG00000134072
Phylogenetic Trees/Animal Genes : TreeFamCAMK1
Homologs : HomoloGeneCAMK1
Homology/Alignments : Family Browser (UCSC)CAMK1
Gene fusions - Rearrangements
Polymorphisms : SNP, variants
NCBI Variation ViewerCAMK1 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)CAMK1
dbVarCAMK1
ClinVarCAMK1
1000_GenomesCAMK1 
Exome Variant ServerCAMK1
ExAC (Exome Aggregation Consortium)CAMK1 (select the gene name)
Genetic variants : HAPMAP8536
Genomic Variants (DGV)CAMK1 [DGVbeta]
Mutations
ICGC Data PortalCAMK1 
TCGA Data PortalCAMK1 
Broad Tumor PortalCAMK1
OASIS PortalCAMK1 [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICCAMK1 
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD - Leiden Open Variation Database
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
BioMutasearch CAMK1
DgiDB (Drug Gene Interaction Database)CAMK1
DoCM (Curated mutations)CAMK1 (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)CAMK1 (select a term)
intoGenCAMK1
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] 
Diseases
DECIPHER (Syndromes)3:9799029-9811668  ENSG00000134072
CONAN: Copy Number AnalysisCAMK1 
Mutations and Diseases : HGMDCAMK1
OMIM604998   
MedgenCAMK1
Genetic Testing Registry CAMK1
NextProtQ14012 [Medical]
TSGene8536
GENETestsCAMK1
Huge Navigator CAMK1 [HugePedia]
snp3D : Map Gene to Disease8536
BioCentury BCIQCAMK1
ClinGenCAMK1
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD8536
Chemical/Pharm GKB GenePA26048
Clinical trialCAMK1
Miscellaneous
canSAR (ICR)CAMK1 (select the gene name)
Probes
Litterature
PubMed55 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineCAMK1
EVEXCAMK1
GoPubMedCAMK1
iHOPCAMK1
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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indexed on : Mon Sep 19 18:39:54 CEST 2016

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