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CAMK1 (calcium/calmodulin-dependent protein kinase I)

Identity

Other namesCAMKI
HGNC (Hugo) CAMK1
LocusID (NCBI) 8536
Location 3p25.3
Location_base_pair Starts at 9799029 and ends at 9811668 bp from pter ( according to hg19-Feb_2009)
Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 

External links

Nomenclature
HGNC (Hugo)CAMK1   1459
Cards
Entrez_Gene (NCBI)CAMK1  8536  calcium/calmodulin-dependent protein kinase I
GeneCards (Weizmann)CAMK1
Ensembl (Hinxton)ENSG00000134072 [Gene_View]  chr3:9799029-9811668 [Contig_View]  CAMK1 [Vega]
ICGC DataPortalENSG00000134072
cBioPortalCAMK1
AceView (NCBI)CAMK1
Genatlas (Paris)CAMK1
WikiGenes8536
SOURCE (Princeton)NM_003656
Genomic and cartography
GoldenPath (UCSC)CAMK1  -  3p25.3   chr3:9799029-9811668 -  3p25.3   [Description]    (hg19-Feb_2009)
EnsemblCAMK1 - 3p25.3 [CytoView]
Mapping of homologs : NCBICAMK1 [Mapview]
OMIM604998   
Gene and transcription
Genbank (Entrez)AA724193 AB451277 AB451407 AK314917 BC106754
RefSeq transcript (Entrez)NM_003656
RefSeq genomic (Entrez)AC_000135 NC_000003 NC_018914 NT_022517 NW_001838876 NW_004929309
Consensus coding sequences : CCDS (NCBI)CAMK1
Cluster EST : UnigeneHs.434875 [ NCBI ]
CGAP (NCI)Hs.434875
Alternative Splicing : Fast-db (Paris)GSHG0021501
Alternative Splicing GalleryENSG00000134072
Gene ExpressionCAMK1 [ NCBI-GEO ]     CAMK1 [ SEEK ]   CAMK1 [ MEM ]
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ14012 (Uniprot)
NextProtQ14012  [Medical]
With graphics : InterProQ14012
Splice isoforms : SwissVarQ14012 (Swissvar)
Catalytic activity : Enzyme2.7.11.17 [ Enzyme-Expasy ]   2.7.11.172.7.11.17 [ IntEnz-EBI ]   2.7.11.17 [ BRENDA ]   2.7.11.17 [ KEGG ]   
Domaine pattern : Prosite (Expaxy)PROTEIN_KINASE_ATP (PS00107)    PROTEIN_KINASE_DOM (PS50011)    PROTEIN_KINASE_ST (PS00108)   
Domains : Interpro (EBI)Ca/CaM-dep_Ca-dep_prot_Kinase [organisation]   Kinase-like_dom [organisation]   Prot_kinase_dom [organisation]   Protein_kinase_ATP_BS [organisation]   Ser/Thr_dual-sp_kinase_dom [organisation]   Ser/Thr_kinase_AS [organisation]  
Related proteins : CluSTrQ14012
Domain families : Pfam (Sanger)Pkinase (PF00069)   
Domain families : Pfam (NCBI)pfam00069   
Domain families : Smart (EMBL)S_TKc (SM00220)  
DMDM Disease mutations8536
Blocks (Seattle)Q14012
PDB (SRS)4FG7    4FG8    4FG9    4FGB   
PDB (PDBSum)4FG7    4FG8    4FG9    4FGB   
PDB (IMB)4FG7    4FG8    4FG9    4FGB   
PDB (RSDB)4FG7    4FG8    4FG9    4FGB   
Human Protein AtlasENSG00000134072 [gene] [tissue] [antibody] [cell] [cancer]
Peptide AtlasQ14012
HPRD05412
IPIIPI00028296   IPI00926719   IPI00927594   IPI00927354   
Protein Interaction databases
DIP (DOE-UCLA)Q14012
IntAct (EBI)Q14012
FunCoupENSG00000134072
BioGRIDCAMK1
InParanoidQ14012
Interologous Interaction database Q14012
IntegromeDBCAMK1
STRING (EMBL)CAMK1
Ontologies - Pathways
Ontology : AmiGOcalmodulin-dependent protein kinase activity  protein binding  calmodulin binding  ATP binding  nucleus  cytoplasm  protein phosphorylation  nucleocytoplasmic transport  cell cycle  signal transduction  positive regulation of neuron projection development  regulation of protein localization  regulation of protein binding  positive regulation of protein export from nucleus  regulation of muscle cell differentiation  positive regulation of muscle cell differentiation  positive regulation of synapse structural plasticity  positive regulation of dendritic spine development  positive regulation of protein serine/threonine kinase activity  
Ontology : EGO-EBIcalmodulin-dependent protein kinase activity  protein binding  calmodulin binding  ATP binding  nucleus  cytoplasm  protein phosphorylation  nucleocytoplasmic transport  cell cycle  signal transduction  positive regulation of neuron projection development  regulation of protein localization  regulation of protein binding  positive regulation of protein export from nucleus  regulation of muscle cell differentiation  positive regulation of muscle cell differentiation  positive regulation of synapse structural plasticity  positive regulation of dendritic spine development  positive regulation of protein serine/threonine kinase activity  
Pathways : BIOCARTACa++/ Calmodulin-dependent Protein Kinase Activation [Genes]    NFAT and Hypertrophy of the heart (Transcription in the broken heart) [Genes]    Regulation of PGC-1a [Genes]    fMLP induced chemokine gene expression in HMC-1 cells [Genes]    Signal Dependent Regulation of Myogenesis by Corepressor MITR [Genes]    Control of skeletal myogenesis by HDAC & calcium/calmodulin-dependent kinase (CaMK) [Genes]   
Protein Interaction DatabaseCAMK1
Wikipedia pathwaysCAMK1
Gene fusion - rearrangments
Polymorphisms : SNP, mutations, diseases
SNP Single Nucleotide Polymorphism (NCBI)CAMK1
snp3D : Map Gene to Disease8536
SNP (GeneSNP Utah)CAMK1
SNP : HGBaseCAMK1
Genetic variants : HAPMAPCAMK1
Exome VariantCAMK1
1000_GenomesCAMK1 
ICGC programENSG00000134072 
Somatic Mutations in Cancer : COSMICCAMK1 
CONAN: Copy Number AnalysisCAMK1 
Mutations and Diseases : HGMDCAMK1
Genomic VariantsCAMK1  CAMK1 [DGVbeta]
dbVarCAMK1
ClinVarCAMK1
Pred. of missensesPolyPhen-2  SIFT(SG)  SIFT(JCVI)  Align-GVGD  MutAssessor  Mutanalyser  
Pred. splicesGeneSplicer  Human Splicing Finder  MaxEntScan  
Diseases
OMIM604998   
MedgenCAMK1
GENETestsCAMK1
Disease Genetic AssociationCAMK1
Huge Navigator CAMK1 [HugePedia]  CAMK1 [HugeCancerGEM]
General knowledge
Homologs : HomoloGeneCAMK1
Homology/Alignments : Family Browser (UCSC)CAMK1
Phylogenetic Trees/Animal Genes : TreeFamCAMK1
Chemical/Protein Interactions : CTD8536
Chemical/Pharm GKB GenePA26048
Clinical trialCAMK1
Cancer Resource (Charite)ENSG00000134072
Other databases
Probes
Litterature
PubMed48 Pubmed reference(s) in Entrez
CoreMineCAMK1
iHOPCAMK1
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

Search in all EBI   NCBI

Contributor(s)

Written09-2002Dessen P, Le Minor S
Updated12-2013Dessen P

© Atlas of Genetics and Cytogenetics in Oncology and Haematology
indexed on : Fri Jul 11 16:47:42 CEST 2014

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