Atlas of Genetics and Cytogenetics in Oncology and Haematology

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CAMK2B (calcium/calmodulin-dependent protein kinase II beta)

Identity

Other namesCAM2
CAMK2
CAMKB
HGNC (Hugo) CAMK2B
LocusID (NCBI) 816
Location 7p13
Location_base_pair Starts at 44256749 and ends at 44365230 bp from pter ( according to hg19-Feb_2009)
Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 

External links

Nomenclature
HGNC (Hugo)CAMK2B   1461
Entrez_Gene (NCBI)CAMK2B  816  calcium/calmodulin-dependent protein kinase II beta
Cards
GeneCards (Weizmann)CAMK2B
Ensembl (Hinxton)ENSG00000058404 [Gene_View]  chr7:44256749-44365230 [Contig_View]  CAMK2B [Vega]
AceView (NCBI)CAMK2B
Genatlas (Paris)CAMK2B
SOURCE (Stanford)NM_001220 NM_172078 NM_172079 NM_172080 NM_172081 NM_172082 NM_172083 NM_172084
Genomic and cartography
GoldenPath (UCSC)CAMK2B  -  7p13   chr7:44256749-44365230 -  7p13   [Description]    (hg19-Feb_2009)
EnsemblCAMK2B - 7p13 [CytoView]
Mapping of homologs : NCBICAMK2B [Mapview]
OMIM607707   
Gene and transcription
Genbank (Entrez)AA399393 AB073352 AF078803 AF081572 AF081924
RefSeq transcript (SRS)NM_001220 NM_172078 NM_172079 NM_172080 NM_172081 NM_172082 NM_172083 NM_172084
RefSeq transcript (Entrez)NM_001220 NM_172078 NM_172079 NM_172080 NM_172081 NM_172082 NM_172083 NM_172084
RefSeq genomic (SRS)AC_000068 AC_000139 NC_000007 NC_018918 NG_029407 NT_007819 NT_079592 NW_001839004 NW_004078029
RefSeq genomic (Entrez)AC_000068 AC_000139 NC_000007 NC_018918 NG_029407 NT_007819 NT_079592 NW_001839004 NW_004078029
Consensus coding sequences : CCDS (NCBI)CAMK2B
Cluster EST : UnigeneHs.351887 [ SRS ] Hs.351887 [ NCBI ]
CGAP (NCI)Hs.351887
Alternative Splicing : Fast-db (Paris)GSHG0028162
Alternative Splicing GalleryENSG00000058404
Gene ExpressionCAMK2B [ NCBI-GEO ]   CAMK2B [ EBI - ARRAY_EXPRESS ]
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ13554 (SRS) Q13554 (Uniprot)
NextProtQ13554
With graphics : InterProQ13554
Splice isoforms : SwissVarQ13554(Swissvar)
Domaine pattern : Prosite (SRS)PROTEIN_KINASE_ATP (PS00107)    PROTEIN_KINASE_DOM (PS50011)    PROTEIN_KINASE_ST (PS00108)   
Domaine pattern : Prosite (Expaxy)PROTEIN_KINASE_ATP (PS00107)    PROTEIN_KINASE_DOM (PS50011)    PROTEIN_KINASE_ST (PS00108)   
Domains : Interpro (SRS)Ca/CaM-dep_Ca-dep_prot_Kinase    Ca/CaM-dep_prot_kinase-assoc    Kinase-like_dom    Prot_kinase_cat_dom    Protein_kinase_ATP_BS    Ser/Thr_dual-sp_kinase_dom    Ser/Thr_kinase_AS   
Domains : Interpro (EBI)Ca/CaM-dep_Ca-dep_prot_Kinase    Ca/CaM-dep_prot_kinase-assoc    Kinase-like_dom    Prot_kinase_cat_dom    Protein_kinase_ATP_BS    Ser/Thr_dual-sp_kinase_dom    Ser/Thr_kinase_AS   
Related proteins : CluSTrQ13554
Domain families : Pfam (SRS)CaMKII_AD (PF08332)    Pkinase (PF00069)   
Domain families : Pfam (Sanger)CaMKII_AD (PF08332)    Pkinase (PF00069)   
Domain families : Pfam (NCBI)pfam08332    pfam00069   
Domain families : Smart (EMBL)S_TKc (SM00220)  
DMDM816
Blocks (Seattle)Q13554
PDB (SRS)3BHH   
PDB (PDBSum)3BHH   
PDB (IMB)3BHH   
PDB (RSDB)3BHH   
Human Protein AtlasENSG00000058404
HPRD12127
IPIIPI00221305   IPI00334271   IPI00219165   IPI00182944   IPI00219166   IPI00298090   IPI00183066   IPI00377174   IPI01009963   IPI00745560   IPI00927384   IPI00925318   IPI00925128   IPI00924912   IPI00926135   IPI00925937   IPI01009631   
Protein Interaction databases
DIP (DOE-UCLA)Q13554
IntAct (EBI)Q13554
FunCoupENSG00000058404
REACTOMECAMK2B
Protein Interaction Database816
BioGRIDCAMK2B
InParanoidQ13554
Interologous Interaction database Q13554
IntegromeDBCAMK2B
Polymorphism : SNP, mutations, diseases
SNP Single Nucleotide Polymorphism (NCBI)CAMK2B
SNP (GeneSNP Utah)CAMK2B
SNP : HGBaseCAMK2B
Genetic variants : HAPMAPCAMK2B
Somatic Mutations in Cancer : COSMICCAMK2B 
CONAN: Copy Number AnalysisCAMK2B 
Mutations and Diseases : HGMDCAMK2B
OMIM607707   
GENETests607707   
Disease Genetic AssociationCAMK2B
Huge Navigator CAMK2B [HugePedia]  CAMK2B [HugeCancerGEM]
Genomic VariantsCAMK2B  CAMK2B [DGVbeta]
snp3D : Map Gene to Disease816
General knowledge
Homologs : HomoloGeneCAMK2B
Homology/Alignments : Family Browser (UCSC)CAMK2B
Phylogenetic Trees/Animal Genes : TreeFamCAMK2B
Chemical/Protein Interactions : CTD816
Chemical/Pharm GKB GenePA91
Clinical trialCAMK2B
Cancer Resource (Charite)ENSG00000058404
Ontology : AmiGOG1/S transition of mitotic cell cycle  inhibitory G-protein coupled receptor phosphorylation  actin binding  calmodulin-dependent protein kinase activity  calmodulin binding  ATP binding  nucleoplasm  microtubule organizing center  cytosol  plasma membrane  protein phosphorylation  calcium ion transport  signal transduction  synaptic transmission  positive regulation of neuron projection development  regulation of skeletal muscle adaptation  peptidyl-serine phosphorylation  cytokine-mediated signaling pathway  endocytic vesicle membrane  regulation of synaptic transmission, cholinergic  sarcoplasmic reticulum membrane  response to cadmium ion  protein autophosphorylation  regulation of long-term neuronal synaptic plasticity  neuromuscular process controlling balance  spindle midzone  regulation of synapse structural plasticity  regulation of calcium ion transport  interferon-gamma-mediated signaling pathway  activation of meiosis involved in egg activation  regulation of dendritic spine development  positive regulation of dendritic spine morphogenesis  positive regulation of synapse maturation  
Ontology : EGO-EBIG1/S transition of mitotic cell cycle  inhibitory G-protein coupled receptor phosphorylation  actin binding  calmodulin-dependent protein kinase activity  calmodulin binding  ATP binding  nucleoplasm  microtubule organizing center  cytosol  plasma membrane  protein phosphorylation  calcium ion transport  signal transduction  synaptic transmission  positive regulation of neuron projection development  regulation of skeletal muscle adaptation  peptidyl-serine phosphorylation  cytokine-mediated signaling pathway  endocytic vesicle membrane  regulation of synaptic transmission, cholinergic  sarcoplasmic reticulum membrane  response to cadmium ion  protein autophosphorylation  regulation of long-term neuronal synaptic plasticity  neuromuscular process controlling balance  spindle midzone  regulation of synapse structural plasticity  regulation of calcium ion transport  interferon-gamma-mediated signaling pathway  activation of meiosis involved in egg activation  regulation of dendritic spine development  positive regulation of dendritic spine morphogenesis  positive regulation of synapse maturation  
Pathways : KEGGWnt signaling pathwayGnRH signaling pathwayCalcium signaling pathwayLong-term potentiationOlfactory transduction
Other databases
Probes
Litterature
PubMed72 Pubmed reference(s) in Entrez
PubGeneCAMK2B
iHOPCAMK2B
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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Contributor(s)

Written09-2002Dessen P, Le Minor S
Updated01-2013Dessen P

© Atlas of Genetics and Cytogenetics in Oncology and Haematology
indexed on : Wed May 1 12:30:47 CEST 2013
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