Atlas of Genetics and Cytogenetics in Oncology and Haematology


Home   Genes   Leukemias   Solid Tumors   Cancer-Prone   Deep Insight   Case Reports   Journals  Portal   Teaching   

X Y 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22 NA

CAMK2B (calcium/calmodulin dependent protein kinase II beta)

Identity

Alias_namesCAMKB
calcium/calmodulin-dependent protein kinase (CaM kinase) II beta
Alias_symbol (synonym)CAM2
CAMK2
Other alias
HGNC (Hugo) CAMK2B
LocusID (NCBI) 816
Atlas_Id 43182
Location 7p13  [Link to chromosome band 7p13]
Location_base_pair Starts at 44217150 and ends at 44325631 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2016)
CAMK2B (7p13) / SPIDR (8q11.21)CAMK2B 7p13 KIAA0146

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


External links

Nomenclature
HGNC (Hugo)CAMK2B   1461
Cards
Entrez_Gene (NCBI)CAMK2B  816  calcium/calmodulin dependent protein kinase II beta
AliasesCAM2; CAMK2; CAMKB
GeneCards (Weizmann)CAMK2B
Ensembl hg19 (Hinxton)ENSG00000058404 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000058404 [Gene_View]  chr7:44217150-44325631 [Contig_View]  CAMK2B [Vega]
ICGC DataPortalENSG00000058404
TCGA cBioPortalCAMK2B
AceView (NCBI)CAMK2B
Genatlas (Paris)CAMK2B
WikiGenes816
SOURCE (Princeton)CAMK2B
Genetics Home Reference (NIH)CAMK2B
Genomic and cartography
GoldenPath hg38 (UCSC)CAMK2B  -     chr7:44217150-44325631 -  7p13   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)CAMK2B  -     7p13   [Description]    (hg19-Feb_2009)
EnsemblCAMK2B - 7p13 [CytoView hg19]  CAMK2B - 7p13 [CytoView hg38]
Mapping of homologs : NCBICAMK2B [Mapview hg19]  CAMK2B [Mapview hg38]
OMIM607707   
Gene and transcription
Genbank (Entrez)###############################################################################################################################################################################################################################################################
RefSeq transcript (Entrez)NM_001220 NM_001293170 NM_172078 NM_172079 NM_172080 NM_172081 NM_172082 NM_172083 NM_172084
RefSeq genomic (Entrez)
Consensus coding sequences : CCDS (NCBI)CAMK2B
Cluster EST : UnigeneHs.351887 [ NCBI ]
CGAP (NCI)Hs.351887
Alternative Splicing GalleryENSG00000058404
Gene ExpressionCAMK2B [ NCBI-GEO ]   CAMK2B [ EBI - ARRAY_EXPRESS ]   CAMK2B [ SEEK ]   CAMK2B [ MEM ]
Gene Expression Viewer (FireBrowse)CAMK2B [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevisibleExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)816
GTEX Portal (Tissue expression)CAMK2B
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ13554   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtQ13554  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProQ13554
Splice isoforms : SwissVarQ13554
PhosPhoSitePlusQ13554
Domaine pattern : Prosite (Expaxy)PROTEIN_KINASE_ATP (PS00107)    PROTEIN_KINASE_DOM (PS50011)    PROTEIN_KINASE_ST (PS00108)   
Domains : Interpro (EBI)Ca/CaM-dep_Ca-dep_prot_Kinase    Ca/CaM-dep_prot_kinase-assoc    Kinase-like_dom    NTF2-like_dom    Prot_kinase_dom    Protein_kinase_ATP_BS    Ser/Thr_kinase_AS   
Domain families : Pfam (Sanger)CaMKII_AD (PF08332)    Pkinase (PF00069)   
Domain families : Pfam (NCBI)pfam08332    pfam00069   
Domain families : Smart (EMBL)S_TKc (SM00220)  
Conserved Domain (NCBI)CAMK2B
DMDM Disease mutations816
Blocks (Seattle)CAMK2B
PDB (SRS)3BHH   
PDB (PDBSum)3BHH   
PDB (IMB)3BHH   
PDB (RSDB)3BHH   
Structural Biology KnowledgeBase3BHH   
SCOP (Structural Classification of Proteins)3BHH   
CATH (Classification of proteins structures)3BHH   
SuperfamilyQ13554
Human Protein AtlasENSG00000058404
Peptide AtlasQ13554
HPRD12127
IPIIPI00221305   IPI00334271   IPI00219165   IPI00182944   IPI00219166   IPI00298090   IPI00183066   IPI00377174   IPI01009963   IPI00745560   IPI00927384   IPI00925318   IPI00925128   IPI00924912   IPI00926135   IPI00925937   IPI01009631   
Protein Interaction databases
DIP (DOE-UCLA)Q13554
IntAct (EBI)Q13554
FunCoupENSG00000058404
BioGRIDCAMK2B
STRING (EMBL)CAMK2B
ZODIACCAMK2B
Ontologies - Pathways
QuickGOQ13554
Ontology : AmiGOMAPK cascade  actin binding  protein serine/threonine kinase activity  calmodulin-dependent protein kinase activity  Ras guanyl-nucleotide exchange factor activity  protein binding  calmodulin binding  ATP binding  nucleoplasm  cytoplasm  microtubule organizing center  cytosol  plasma membrane  protein phosphorylation  signal transduction  positive regulation of neuron projection development  regulation of skeletal muscle adaptation  sarcoplasmic reticulum  peptidyl-serine phosphorylation  peptidyl-threonine phosphorylation  endocytic vesicle membrane  sarcoplasmic reticulum membrane  intracellular signal transduction  protein homodimerization activity  neuron projection  positive regulation of GTPase activity  protein autophosphorylation  regulation of long-term neuronal synaptic plasticity  regulation of synapse structural plasticity  regulation of calcium ion transport  interferon-gamma-mediated signaling pathway  regulation of dendritic spine development  positive regulation of dendritic spine morphogenesis  positive regulation of synapse maturation  regulation of cellular response to heat  
Ontology : EGO-EBIMAPK cascade  actin binding  protein serine/threonine kinase activity  calmodulin-dependent protein kinase activity  Ras guanyl-nucleotide exchange factor activity  protein binding  calmodulin binding  ATP binding  nucleoplasm  cytoplasm  microtubule organizing center  cytosol  plasma membrane  protein phosphorylation  signal transduction  positive regulation of neuron projection development  regulation of skeletal muscle adaptation  sarcoplasmic reticulum  peptidyl-serine phosphorylation  peptidyl-threonine phosphorylation  endocytic vesicle membrane  sarcoplasmic reticulum membrane  intracellular signal transduction  protein homodimerization activity  neuron projection  positive regulation of GTPase activity  protein autophosphorylation  regulation of long-term neuronal synaptic plasticity  regulation of synapse structural plasticity  regulation of calcium ion transport  interferon-gamma-mediated signaling pathway  regulation of dendritic spine development  positive regulation of dendritic spine morphogenesis  positive regulation of synapse maturation  regulation of cellular response to heat  
Pathways : KEGG   
NDEx NetworkCAMK2B
Atlas of Cancer Signalling NetworkCAMK2B
Wikipedia pathwaysCAMK2B
Orthology - Evolution
OrthoDB816
GeneTree (enSembl)ENSG00000058404
Phylogenetic Trees/Animal Genes : TreeFamCAMK2B
HOVERGENQ13554
HOGENOMQ13554
Homologs : HomoloGeneCAMK2B
Homology/Alignments : Family Browser (UCSC)CAMK2B
Gene fusions - Rearrangements
Fusion : MitelmanCAMK2B/SPIDR [7p13/8q11.21]  
Fusion: TCGACAMK2B 7p13 KIAA0146 LUAD
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerCAMK2B [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)CAMK2B
dbVarCAMK2B
ClinVarCAMK2B
1000_GenomesCAMK2B 
Exome Variant ServerCAMK2B
ExAC (Exome Aggregation Consortium)CAMK2B (select the gene name)
Genetic variants : HAPMAP816
Genomic Variants (DGV)CAMK2B [DGVbeta]
DECIPHERCAMK2B [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisCAMK2B 
Mutations
ICGC Data PortalCAMK2B 
TCGA Data PortalCAMK2B 
Broad Tumor PortalCAMK2B
OASIS PortalCAMK2B [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICCAMK2B  [overview]  [genome browser]  [tissue]  [distribution]  
Mutations and Diseases : HGMDCAMK2B
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD - Leiden Open Variation Database
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
BioMutasearch CAMK2B
DgiDB (Drug Gene Interaction Database)CAMK2B
DoCM (Curated mutations)CAMK2B (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)CAMK2B (select a term)
intoGenCAMK2B
Cancer3DCAMK2B(select the gene name)
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM607707   
Orphanet
MedgenCAMK2B
Genetic Testing Registry CAMK2B
NextProtQ13554 [Medical]
TSGene816
GENETestsCAMK2B
Target ValidationCAMK2B
Huge Navigator CAMK2B [HugePedia]
snp3D : Map Gene to Disease816
BioCentury BCIQCAMK2B
ClinGenCAMK2B
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD816
Chemical/Pharm GKB GenePA91
Clinical trialCAMK2B
Miscellaneous
canSAR (ICR)CAMK2B (select the gene name)
Probes
Litterature
PubMed80 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineCAMK2B
EVEXCAMK2B
GoPubMedCAMK2B
iHOPCAMK2B
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

Search in all EBI   NCBI

© Atlas of Genetics and Cytogenetics in Oncology and Haematology
indexed on : Mon Sep 25 19:00:21 CEST 2017

Home   Genes   Leukemias   Solid Tumors   Cancer-Prone   Deep Insight   Case Reports   Journals  Portal   Teaching   

For comments and suggestions or contributions, please contact us

jlhuret@AtlasGeneticsOncology.org.