Atlas of Genetics and Cytogenetics in Oncology and Haematology

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CAMK2N1 (calcium/calmodulin dependent protein kinase II inhibitor 1)

Identity

Alias_symbol (synonym)CaMKIINalpha
Other aliasPRO1489
HGNC (Hugo) CAMK2N1
LocusID (NCBI) 55450
Atlas_Id 907
Location 1p36.12  [Link to chromosome band 1p36]
Location_base_pair Starts at 20482391 and ends at 20486235 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2017)		Data from Atlas, Mitelman, Cosmic Fusion, Fusion Cancer, TCGA fusion databases with official HUGO symbols (see references in chromosomal bands)
CAMK2N1 (1p36.12) / ABCD3 (1p21.3)CAMK2N1 (1p36.12) / BRINP3 (1q31.1)CAMK2N1 (1p36.12) / CAMK2N1 (1p36.12)
CAMK2N1 (1p36.12) / LPGAT1 (1q32.3)CARD10 (22q13.1) / CAMK2N1 (1p36.12)NAALADL2 (3q26.31) / CAMK2N1 (1p36.12)

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 

External links

Nomenclature
HGNC (Hugo)CAMK2N1   24190
Cards
Entrez_Gene (NCBI)CAMK2N1  55450  calcium/calmodulin dependent protein kinase II inhibitor 1
AliasesPRO1489
GeneCards (Weizmann)CAMK2N1
Ensembl hg19 (Hinxton)ENSG00000162545 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000162545 [Gene_View]  chr1:20482391-20486235 [Contig_View]  CAMK2N1 [Vega]
ICGC DataPortalENSG00000162545
TCGA cBioPortalCAMK2N1
AceView (NCBI)CAMK2N1
Genatlas (Paris)CAMK2N1
WikiGenes55450
SOURCE (Princeton)CAMK2N1
Genetics Home Reference (NIH)CAMK2N1
Genomic and cartography
GoldenPath hg38 (UCSC)CAMK2N1  -     chr1:20482391-20486235 -  1p36.12   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)CAMK2N1  -     1p36.12   [Description]    (hg19-Feb_2009)
EnsemblCAMK2N1 - 1p36.12 [CytoView hg19]  CAMK2N1 - 1p36.12 [CytoView hg38]
Mapping of homologs : NCBICAMK2N1 [Mapview hg19]  CAMK2N1 [Mapview hg38]
OMIM614986   
Gene and transcription
Genbank (Entrez)AY204901 BC020630 BI820748 DB475389
RefSeq transcript (Entrez)NM_018584
RefSeq genomic (Entrez)
Consensus coding sequences : CCDS (NCBI)CAMK2N1
Cluster EST : UnigeneHs.731383 [ NCBI ]
CGAP (NCI)Hs.731383
Alternative Splicing GalleryENSG00000162545
Gene ExpressionCAMK2N1 [ NCBI-GEO ]   CAMK2N1 [ EBI - ARRAY_EXPRESS ]   CAMK2N1 [ SEEK ]   CAMK2N1 [ MEM ]
Gene Expression Viewer (FireBrowse)CAMK2N1 [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevestigatorExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)55450
GTEX Portal (Tissue expression)CAMK2N1
Human Protein AtlasENSG00000162545-CAMK2N1 [pathology]   [cell]   [tissue]
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ7Z7J9   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtQ7Z7J9  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProQ7Z7J9
Splice isoforms : SwissVarQ7Z7J9
PhosPhoSitePlusQ7Z7J9
Domains : Interpro (EBI)Camk2n   
Domain families : Pfam (Sanger)CaM-KIIN (PF15170)   
Domain families : Pfam (NCBI)pfam15170   
Conserved Domain (NCBI)CAMK2N1
DMDM Disease mutations55450
Blocks (Seattle)CAMK2N1
SuperfamilyQ7Z7J9
Human Protein Atlas [tissue]ENSG00000162545-CAMK2N1 [tissue]
Peptide AtlasQ7Z7J9
HPRD13112
IPIIPI00163768   IPI00383367   
Protein Interaction databases
DIP (DOE-UCLA)Q7Z7J9
IntAct (EBI)Q7Z7J9
FunCoupENSG00000162545
BioGRIDCAMK2N1
STRING (EMBL)CAMK2N1
ZODIACCAMK2N1
Ontologies - Pathways
QuickGOQ7Z7J9
Ontology : AmiGOintracellular  negative regulation of protein kinase activity  negative regulation of cell proliferation  calcium-dependent protein kinase inhibitor activity  positive regulation of gene expression  postsynaptic density  protein kinase binding  cell junction  dendrite  neuronal cell body  postsynaptic membrane  negative regulation of cell cycle  negative regulation of proteolysis  negative regulation of ERK1 and ERK2 cascade  negative regulation of cyclin-dependent protein kinase activity  
Ontology : EGO-EBIintracellular  negative regulation of protein kinase activity  negative regulation of cell proliferation  calcium-dependent protein kinase inhibitor activity  positive regulation of gene expression  postsynaptic density  protein kinase binding  cell junction  dendrite  neuronal cell body  postsynaptic membrane  negative regulation of cell cycle  negative regulation of proteolysis  negative regulation of ERK1 and ERK2 cascade  negative regulation of cyclin-dependent protein kinase activity  
NDEx NetworkCAMK2N1
Atlas of Cancer Signalling NetworkCAMK2N1
Wikipedia pathwaysCAMK2N1
Orthology - Evolution
OrthoDB55450
GeneTree (enSembl)ENSG00000162545
Phylogenetic Trees/Animal Genes : TreeFamCAMK2N1
HOVERGENQ7Z7J9
HOGENOMQ7Z7J9
Homologs : HomoloGeneCAMK2N1
Homology/Alignments : Family Browser (UCSC)CAMK2N1
Gene fusions - Rearrangements
Fusion : QuiverCAMK2N1
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerCAMK2N1 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)CAMK2N1
dbVarCAMK2N1
ClinVarCAMK2N1
1000_GenomesCAMK2N1 
Exome Variant ServerCAMK2N1
ExAC (Exome Aggregation Consortium)ENSG00000162545
GNOMAD BrowserENSG00000162545
Genetic variants : HAPMAP55450
Genomic Variants (DGV)CAMK2N1 [DGVbeta]
DECIPHERCAMK2N1 [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisCAMK2N1 
Mutations
ICGC Data PortalCAMK2N1 
TCGA Data PortalCAMK2N1 
Broad Tumor PortalCAMK2N1
OASIS PortalCAMK2N1 [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICCAMK2N1  [overview]  [genome browser]  [tissue]  [distribution]  
Mutations and Diseases : HGMDCAMK2N1
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
BioMutasearch CAMK2N1
DgiDB (Drug Gene Interaction Database)CAMK2N1
DoCM (Curated mutations)CAMK2N1 (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)CAMK2N1 (select a term)
intoGenCAMK2N1
Cancer3DCAMK2N1(select the gene name)
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM614986   
Orphanet
DisGeNETCAMK2N1
MedgenCAMK2N1
Genetic Testing Registry CAMK2N1
NextProtQ7Z7J9 [Medical]
TSGene55450
GENETestsCAMK2N1
Target ValidationCAMK2N1
Huge Navigator CAMK2N1 [HugePedia]
snp3D : Map Gene to Disease55450
BioCentury BCIQCAMK2N1
ClinGenCAMK2N1
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD55450
Chemical/Pharm GKB GenePA142672209
Clinical trialCAMK2N1
Miscellaneous
canSAR (ICR)CAMK2N1 (select the gene name)
Probes
Litterature
PubMed9 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineCAMK2N1
EVEXCAMK2N1
GoPubMedCAMK2N1
iHOPCAMK2N1
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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indexed on : Mon May 14 11:34:31 CEST 2018
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