CAMK2N2 (calcium/calmodulin dependent protein kinase II inhibitor 2)

2009-11-01  

Identity

HGNC
LOCATION
3q27.1
LOCUSID
ALIAS
CAM-KIIN,CAMKIIN
FUSION GENES

Other Information

Locus ID:

NCBI: 94032
MIM: 608721
HGNC: 24197
Ensembl: ENSG00000163888

Variants:

dbSNP: 94032
ClinVar: 94032
TCGA: ENSG00000163888
COSMIC: CAMK2N2

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000163888ENST00000296238Q96S95

Expression (GTEx)

0
10
20
30
40
50
60
70
80
90
100

Protein levels (Protein atlas)

Not detected
Low
Medium
High

References

Pubmed IDYearTitleCitations
97248001998Characterization of a calmodulin kinase II inhibitor protein in brain.110
195869092009Endogenous human CaMKII inhibitory protein suppresses tumor growth by inducing cell cycle arrest and apoptosis through down-regulation of the phosphatidylinositide 3-kinase/Akt/HDM2 pathway.17
231539282013Downregulation of extracellular signal-regulated kinase 1/2 activity by calmodulin KII modulates p21Cip1 levels and survival of immortalized lymphocytes from Alzheimer's disease patients.12
204870312010Differential regulation of CaMKII inhibitor beta protein expression after exposure to a novel context and during contextual fear memory formation.7
235451172013Genome wide array analysis indicates that an amyotrophic lateral sclerosis mutation of FUS causes an early increase of CAMK2N2 in vitro.6

Citation

Dessen P

CAMK2N2 (calcium/calmodulin dependent protein kinase II inhibitor 2)

Atlas Genet Cytogenet Oncol Haematol. 2009-11-01

Online version: http://atlasgeneticsoncology.org/gene/51232/camk2n2